Rabbit Anti-TF2A1 Antibody – Cat# MBS000231

TF2A1 Antibody – Rabbit

Name: TF2A1 Antibody; Rabbit; Human/Mouse/Rat-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS000231
Price: 595 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS000231

MBS000231 is an antibody targeting TF2A1. Also known as Rabbit TF2A1 Antibody. Reactive in Human, mouse, rat. Host: Rabbit. More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Product Name

TF2A1, Antibody

Full Product Name

Rabbit TF2A1 Antibody

Product Gene Name

anti-TF2A1 antibody

Host

Rabbit

Species Reactivity

Human, mouse, rat

Form/Format

Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol

Concentration

1 mg/ml (lot specific)

Molecular Weight

41,514 Da

Chromosome Location

Chromosome: 14; NC_000014.8 (81641796..81687575, complement). Location: 14q31.1

OMIM

600520

3D Structure

ModBase 3D Structure for P52655

Applications Tested/Suitable for anti-TF2A1 antibody

ELISA (EIA), Western Blot (WB)

Other Notes

Small volumes of anti-TF2A1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for TF2A1. It may not necessarily be applicable to this product.

NCBI GI #

7706735

NCBI GeneID

2957

NCBI Accession #

NP_056943.1

UniProt Primary Accession #

P52655

UniProt Secondary Accession #

Q3KNQ9

UniProt Related Accession #

P52655

GenBank Nucleotide #

NM_015859.3

NCBI Official Full Name

transcription initiation factor IIA subunit 1 isoform 1

NCBI Official Synonym Full Names

general transcription factor IIA, 1, 19/37kDa

NCBI Official Symbol

GTF2A1

NCBI Official Synonym Symbols

TF2A1; TFIIA; TFIIAL; TFIIA-42

UniProt Protein Name

Transcription initiation factor IIA subunit 1

UniProt Synonym Protein Names

General transcription factor IIA subunit 1; TFIIAL; Transcription initiation factor TFIIA 42 kDa subunit; TFIIA-42Cleaved into the following 2 chains:Transcription initiation factor IIA alpha chain; Alternative name(s):; TFIIA p35 subunitTranscription initiation factor IIA beta chain; Alternative name(s):; TFIIA p19 subunit

UniProt Gene Name

GTF2A1

UniProt Synonym Gene Names

TF2A1; TFIIA-42

UniProt Entry Name

TF2AA_HUMAN

NCBI Protein Information

transcription initiation factor IIA subunit 1; TFIIA alpha, p55, isoform 1; general transcription factor IIA subunit 1; glucose regulated protein, 58kD pseudogene; transcription initiation factor TFIIA 42 kDa subunit

NCBI Summary for TF2A1

Accurate transcription initiation on TATA-containing class II genes involves the ordered assembly of RNA polymerase II (POLR2A; MIM 180660) and several general initiation factors (summarized by DeJong and Roeder, 1993 [PubMed 8224848]). One of these factors is TFIIA, which when purified from HeLa extracts consists of 35-, 19-, and 12-kD subunits.[supplied by OMIM, Jul 2010]

UniProt Comments for TF2A1

GTF2A1: a general transcription factor that plays an important role in transcriptional activation. A component of the transcription machinery of RNA polymerase II. Phosphorylated by Taf(II) 250 on serines that regulate TBP binding. Interacts with TBP (the TATA-binding protein). Two isoforms, 42 kDa and 37 kDa, are produced by alternative initiation.

Protein type: Transcription, coactivator/corepressor

Chromosomal Location of Human Ortholog: 14q31.1

Cellular Component: nucleoplasm; cytoplasm; transcription factor TFIIA complex

Molecular Function: protein binding; DNA binding; TATA-binding protein binding; protein heterodimerization activity; transcription coactivator activity; transcription factor binding

Biological Process: transcription from RNA polymerase II promoter; transcription initiation from RNA polymerase II promoter; regulation of transcription, DNA-dependent; viral reproduction; RNA elongation from RNA polymerase II promoter; gene expression

Research Articles on TF2A1

1. GTF2A1 alone, or GTF2A1 plus HAAO are excellent candidate biomarkers for detecting Ovarian cancer

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-TF2A1 antibody

Reference Product	PubMed Publications
TBP antibody	>1 publications with TF2A1 and TBP
GTF2A2 antibody	>1 publications with TF2A1 and GTF2A2

Pathways associated with anti-TF2A1 antibody

Products by Pathway	Pathway Diagram
Basal Transcription Factors Pathway antibodies	Basal Transcription Factors Pathway Diagram
Basal Transcription Factors Pathway antibodies	Basal Transcription Factors Pathway Diagram
Disease Pathway antibodies	Disease Pathway Diagram
Gene Expression Pathway antibodies	Gene Expression Pathway Diagram
HIV Infection Pathway antibodies	HIV Infection Pathway Diagram
HIV Life Cycle Pathway antibodies	HIV Life Cycle Pathway Diagram
HIV-1 Transcription Initiation Pathway antibodies	HIV-1 Transcription Initiation Pathway Diagram
Late Phase Of HIV Life Cycle Pathway antibodies	Late Phase Of HIV Life Cycle Pathway Diagram
RNA Polymerase II HIV-1 Promoter Escape Pathway antibodies	RNA Polymerase II HIV-1 Promoter Escape Pathway Diagram
RNA Polymerase II Pre-transcription Events Pathway antibodies	RNA Polymerase II Pre-transcription Events Pathway Diagram

Diseases associated with anti-TF2A1 antibody

Disease Name	Pubmed Publications
Neoplasms Antibodies	>2 publications with TF2A1 and Neoplasms
Ovarian Diseases Antibodies	>1 publications with TF2A1 and Ovarian Diseases
Ovarian Neoplasms Antibodies	>1 publications with TF2A1 and Ovarian Neoplasms

Organs/Tissues associated with anti-TF2A1 antibody

Organ/Tissue Name	Pubmed Publications
Stomach Antibodies	>1 publications with TF2A1 and Stomach
Testis Antibodies	>1 publications with TF2A1 and Testis