MOUSE CXCL13 Recombinant Protein – Cat# MBS232348

CXCL13 MOUSE Recombinant Protein

Name: CXCL13 Recombinant Protein; MOUSE; MyBioSource
Brand: MyBioSource
SKU: MBS232348
Price: 585 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS232348

Mouse B lymphocyte chemoattractant (BLC) is a 9.5kD chemokine, also known CXCL13. BLC is strongly expressed in the spleen, lymph nodes and Peyers Patches. BLC is chemotactic for B lymphocytes. More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Product Name

CXCL13, Recombinant Protein

Full Product Name

RECOMBINANT MOUSE CXCL13

Product Gene Name

CXCL13 recombinant protein

Form/Format

Purified Recombinant Protein - lyophilised

Purity/Purification

>99% by SDS PAGE and HPLC analysis

Concentration

Approximate Protein Concentration: 1.0 mg/ml (lot specific)

Preparation and Storage

Prior to reconstitution store at 4 degree C. Following reconstitution store at -20 degree C. This product should be stored undiluted. Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the protein. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 3 months from date of reconstitution.

Molecular Weight

11,927 Da

3D Structure

ModBase 3D Structure for O55038

Reconstitution

Reconstitute with 20 ul distilled water. Care should be taken during reconstitution as the protein may appear as a film at the bottom of the vial. MyBioSource recommends that the vial is gently mixed after reconstitution.
Preparation||Recombinant protein expressed in E Coli

Target Species

Mouse

Applications Tested/Suitable for CXCL13 recombinant protein

Functional Assays (FN)

Other Notes

Small volumes of CXCL13 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CXCL13 purchase

MBS232348 is a recombinant protein targeting CXCL13. Also known as RECOMBINANT MOUSE CXCL13.

Additional Details

NCBI/Uniprot data below describe general gene information for CXCL13. It may not necessarily be applicable to this product.

NCBI GI #

9256521

NCBI GeneID

55985

NCBI Accession #

NP_061354.1

UniProt Primary Accession #

O55038

UniProt Related Accession #

O55038

GenBank Nucleotide #

NM_018866.2

NCBI Official Full Name

C-X-C motif chemokine 13

NCBI Official Synonym Full Names

chemokine (C-X-C motif) ligand 13

NCBI Official Symbol

Cxcl13

NCBI Official Synonym Symbols

BLC; Angie; BCA-1; BLR1L; ANGIE2; Scyb13; 4631412M08Rik

UniProt Protein Name

C-X-C motif chemokine 13

UniProt Synonym Protein Names

B lymphocyte chemoattractant; CXC chemokine BLC; Small-inducible cytokine B13

Protein Family

C-X-C motif chemokine

UniProt Gene Name

Cxcl13

UniProt Synonym Gene Names

Blc; Scyb13

UniProt Entry Name

CXL13_MOUSE

NCBI Protein Information

C-X-C motif chemokine 13; B lymphocyte chemoattractant; CXC chemokine BLC; small inducible cytokine subfamily B (Cys-X-Cys), member 13; small-inducible cytokine B13

UniProt Comments for CXCL13

CXCL13: Chemotactic for B-lymphocytes but not for T-lymphocytes, monocytes and neutrophils. Does not induce calcium release in B- lymphocytes. Binds to BLR1/CXCR5. Belongs to the intercrine alpha (chemokine CxC) family.

Protein type: Secreted; Motility/polarity/chemotaxis; Secreted, signal peptide

Cellular Component: extracellular space; cell; extracellular region; cytosol

Molecular Function: heparin binding; fibroblast growth factor binding; CXCR3 chemokine receptor binding; chemokine activity; protein heterodimerization activity; CCR10 chemokine receptor binding; CXCR5 chemokine receptor binding; cytokine activity; receptor agonist activity

Biological Process: lymphocyte chemotaxis across high endothelial venule; positive regulation of leukocyte chemotaxis; response to lipopolysaccharide; chemotaxis; positive regulation of integrin activation; positive regulation of cell-cell adhesion mediated by integrin; lymph node development; regulation of cell proliferation; G-protein coupled receptor protein signaling pathway; elevation of cytosolic calcium ion concentration; cell surface receptor linked signal transduction; cell-cell signaling; defense response to bacterium; immune response; inflammatory response

Research Articles on CXCL13

1. Data suggest that Src homology 3 (SH3) protein interacting with NcK, 90 kDa (SPIN90)plays an important role in B cell immune responses through the regulation of chemokine CXCL13-mediated B cell migration.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with CXCL13 recombinant protein

Reference Product	PubMed Publications
Cxcr5 recombinant protein	>190 publications with CXCL13 and Cxcr5
Cxcl12 recombinant protein	>128 publications with CXCL13 and Cxcl12
Cxcr4 recombinant protein	>59 publications with CXCL13 and Cxcr4
Ccr7 recombinant protein	>51 publications with CXCL13 and Ccr7
Cxcl9 recombinant protein	>29 publications with CXCL13 and Cxcl9
Cxcr3 recombinant protein	>28 publications with CXCL13 and Cxcr3
Ccr2 recombinant protein	>9 publications with CXCL13 and Ccr2
Cxcr1 recombinant protein	>8 publications with CXCL13 and Cxcr1
Cxcr2 recombinant protein	>7 publications with CXCL13 and Cxcr2

Pathways associated with CXCL13 recombinant protein

Products by Pathway	Pathway Diagram
Chemokine Receptors Bind Chemokines Pathway antibodies	Chemokine Receptors Bind Chemokines Pathway Diagram
Chemokine Signaling Pathway antibodies	Chemokine Signaling Pathway Diagram
Chemokine Signaling Pathway antibodies	Chemokine Signaling Pathway Diagram
Chemokine Signaling Pathway antibodies	Chemokine Signaling Pathway Diagram
Class A/1 (Rhodopsin-like Receptors) Pathway antibodies	Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
Cytokine-cytokine Receptor Interaction Pathway antibodies	Cytokine-cytokine Receptor Interaction Pathway Diagram
Cytokine-cytokine Receptor Interaction Pathway antibodies	Cytokine-cytokine Receptor Interaction Pathway Diagram
Defective ACTH Causes Obesity And Pro-opiomelanocortinin Deficiency (POMCD) Pathway antibodies	Defective ACTH Causes Obesity And Pro-opiomelanocortinin Deficiency (POMCD) Pathway Diagram
Disease Pathway antibodies	Disease Pathway Diagram
G Alpha (i) Signalling Events Pathway antibodies	G Alpha (i) Signalling Events Pathway Diagram

Diseases associated with CXCL13 recombinant protein

Disease Name	Pubmed Publications
Inflammation Antibodies	>154 publications with CXCL13 and Inflammation
Necrosis Antibodies	>58 publications with CXCL13 and Necrosis
Disease Models, Animal Antibodies	>49 publications with CXCL13 and Disease Models, Animal
Lung Diseases Antibodies	>31 publications with CXCL13 and Lung Diseases
Carcinoma Antibodies	>30 publications with CXCL13 and Carcinoma
Kidney Diseases Antibodies	>20 publications with CXCL13 and Kidney Diseases
Hyperplasia Antibodies	>19 publications with CXCL13 and Hyperplasia
Neoplasms, Experimental Antibodies	>18 publications with CXCL13 and Neoplasms, Experimental
Liver Diseases Antibodies	>14 publications with CXCL13 and Liver Diseases
Adenocarcinoma Antibodies	>12 publications with CXCL13 and Adenocarcinoma

Organs/Tissues associated with CXCL13 recombinant protein

Organ/Tissue Name	Pubmed Publications
Lymph Node Antibodies	>179 publications with CXCL13 and Lymph Node
Spleen Antibodies	>80 publications with CXCL13 and Spleen
Lung Antibodies	>44 publications with CXCL13 and Lung
Skin Antibodies	>38 publications with CXCL13 and Skin
Kidney Antibodies	>24 publications with CXCL13 and Kidney
Thymus Antibodies	>21 publications with CXCL13 and Thymus
Intestine Antibodies	>20 publications with CXCL13 and Intestine
Muscle Antibodies	>20 publications with CXCL13 and Muscle
Stomach Antibodies	>7 publications with CXCL13 and Stomach
Extraembryonic Tissue Antibodies	>1 publications with CXCL13 and Extraembryonic Tissue