WEST NILE VIRUS (WEST) Recombinant Protein

Recombinant West Nile Virus NS1 Antigen is a purified preparation of the West Nile virus non-structural protein 1 (NS1).West Nile Virus (WNV), also known as West Nile Fever, is primarily a mosquito borne virus belonging the Flaviviridae family. In humans the majority of infections are subclinical with patients experiencing either no or very mild symptoms, however a minority of infections result in severe disease, which may result in fatal encephalitis.Originating in Africa, WNV was, until recently, not a signifinant disease of humans. Since the the late 1990's the virus has spread widely to other continents and is now an endemic pathogen in the temperate and tropic reagions throughout the world. WNV infection is now considered a serious health concern in North America (Lindsey et al. 2014).WNV is zoonotic disease with an avian wildlife resevoir to which passerine and more specifcally, corvid species appear to be particularly susceptible with high recorded mortality rates (Abdelrazec et al. 2014). In addition to the human health concerns and the effect on North American avian species populations (Wheeler et al. 2011), WNV is also of potential concern in domestic mammals, in particular to equine species where mortality rates are high (Agenvoort et al. 2013). Fatal cases of West Nile have also been noted other species including non-human primates, bats and cetaceans. While the primary route of infection is via mosquitos there is some evidence that infection may also occur from other invertebrate species such as ticks, however further research is required in this area.Recombinant West Nile virus NS1 antigen is presented in its native folded state complete with post-translational modifications, delivering optimal antigenicity and making it suitable for use in vaccine research and serology-based assays.

Small volumes of WEST NILE VIRUS recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS232529 is a recombinant protein targeting WEST NILE VIRUS. Also known as RECOMBINANT WEST NILE VIRUS NS1 ANTIGEN.