Both cells are apoptotic (green) and dying (blue nuclei). As the left cell is much brighter green than the right cell, the left cell had more active caspases

CASPASE-8 (CASP8) Assay Kit

Name: CASP8 Assay Kit; CASPASE-8; MyBioSource
Brand: MyBioSource
SKU: MBS239195
Price: 1315 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS239195

Description: The FAM FLICA Caspase 8 kit uses a quick and easy method to analyze active caspases in apoptotic cells.Test Principle: Caspase FLICA kits measure apoptosis by detecting active caspases in whole, living cells. These kits do not work by using… More details

$1315 / 100 Tests +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Request Current Manual

Product Overview

Online Datasheet in PDF

Product Name

CASPASE-8 (CASP8), Assay Kit

Full Product Name

FAM FLICA CASPASE-8 KIT

Product Gene Name

CASP8 assay kit

Form/Format

Kit

Preparation and Storage

Store the unopened kit (and each unopened component) at 4 degree C until the expiration date.
Protect the FLICA reagent from light at all times.
Once reconstituted, the 150X FLICA stock should be stored at -20 degree C protected from light.
Shelf Life: The 150X FLICA reconstituted stock is stable for up to 6 months and may be thawed twice during that time.

Reagents In The Kits

4 vials of FAM-LETD-FMK FLICA Reagent - lyophilized
10X Wash Buffer, 60 mL
Fixative, 6 mL
Propidium Iodide, 1 mL
Hoechst Stain, 1 mL

Applications Tested/Suitable for CASP8 assay kit

Flow cytometry (FC/FACS), Immunofluorescence (IF)

Other Notes

Small volumes of CASP8 assay kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CASP8 purchase

MBS239195 is an assay kit targeting CASP8. Also known as FAM FLICA CASPASE-8 KIT.

Additional Details

NCBI/Uniprot data below describe general gene information for CASP8. It may not necessarily be applicable to this product.

NCBI GI #

NCBI GeneID

NCBI Accession #

GenBank Nucleotide #

NCBI Official Full Name

caspase-8

NCBI Official Synonym Full Names

caspase 8, apoptosis-related cysteine peptidase

NCBI Official Symbol

CASP8

NCBI Official Synonym Symbols

caspase-8

Protein Family

Caspase

NCBI Protein Information

caspase-8; caspase 8, apoptosis-related cysteine protease

Research Articles on CASP8

1. These results suggest that TRAIL inhibits VEGF-induced angiogenesis by increasing caspase-8 activity and subsequently decreasing non-apoptotic signaling functions of procaspase-8, without inducing caspase-3 activation and endothelial cell cytotoxicity.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with CASP8 assay kit

Products by Pathway	Pathway Diagram
Androgen Receptor Signaling Pathway antibodies	Androgen Receptor Signaling Pathway Diagram
Apoptosis Pathway antibodies	Apoptosis Pathway Diagram
Apoptosis Pathway antibodies	Apoptosis Pathway Diagram
Apoptosis Pathway antibodies	Apoptosis Pathway Diagram
FAS Pathway And Stress Induction Of HSP Regulation antibodies	FAS Pathway And Stress Induction Of HSP Regulation Diagram
Herpes Simplex Infection Pathway antibodies	Herpes Simplex Infection Pathway Diagram
Herpes Simplex Infection Pathway antibodies	Herpes Simplex Infection Pathway Diagram
MAPK Signaling Pathway antibodies	MAPK Signaling Pathway Diagram
NOD-like Receptor Signaling Pathway antibodies	NOD-like Receptor Signaling Pathway Diagram
NOD-like Receptor Signaling Pathway antibodies	NOD-like Receptor Signaling Pathway Diagram