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BRS3 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS240087

BRS3 is classified as an Orphan-A Receptor and is highly similar to the bombesin receptors but has a very low affinity for bombesin itself. Mice lacking BRS3 develop metabolic defects and obesity, suggesting that BRS3 may be an important target for obesity… More details

$650 / 0.05 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
BRS3 / BRS-3, Polyclonal Antibody
Full Product Name
Rabbit Polyclonal to Human BRS3 / BRS-3
Product Gene Name
Product Synonym Gene Name
BRS-3
Product Synonym Names
Anti-BRS3 / BRS-3 Antibody (Cytoplasmic Domain) IHC-plus; BRS3; BB3 receptor; Bombesin-like receptor 3; Bombesin receptor subtype 3; Bombesin receptor subtype-3; BRS-3; BLP receptor subtype 3; Bombesin receptor 3; Human BRS3; BRS-3
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Bat, Gibbon, Bovine, Dog, Guinea pig, Gorilla, Hamster, Horse, Human, Monkey, Mouse, Rabbit, Rat, Sheep
Predicted Reactivity: Chicken (at least 90% immunogen sequence identity)
Form/Format
PBS, 0.1% sodium azide.
Purity/Purification
Immunoaffinity Purified
Concentration
1 mg/ml (lot specific)
Specificity
Human BRS3. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Preparation and Storage
Long term: -70 degree C; Short term: +4 degree C
Molecular Weight
44,411 Da
OMIM
300107
3D Structure
ModBase 3D Structure for P32247
Target Species
Human
Immunogen Description
Synthetic 18 amino acid peptide from 1st cytoplasmic domain of human BRS3.
Immunogen Type
Synthetic peptide
Immunogen
BRS3 / BRS-3 antibody was raised against synthetic 18 amino acid peptide from 1st cytoplasmic domain of human BRS3. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Sheep, Bovine, Dog, Bat, Hamster, Panda, Horse, Rabbit, Guinea pig (100%); Elephant, Turkey, Chicken, Platypus (94%); Xenopus (89%); Opossum (83%).
Antigen Modification
Cytoplasmic Domain
Applications Tested/Suitable for anti-BRS3 antibody
Immunohistochemistry (IHC - Paraffin), ELISA (EIA)
Application Notes for anti-BRS3 antibody
ELISA, IHC-P (10 ug/ml)
Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary anti...

Immunohistochemistry (IHC) of anti-BRS3 antibody

Anti-BRS3 antibody IHC of human uterus, pregnant. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Rabbit Anti-BRS3 Polyclonal Antibody – Cat# MBS240087

Other Notes

Small volumes of anti-BRS3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for BRS3 purchase

MBS240087 is an antibody targeting BRS3. Also known as Rabbit Polyclonal to Human BRS3 / BRS-3. Reactive in Bat, Gibbon, Bovine, Dog, Guinea pig, Gorilla, Hamster, Horse, Human, Monkey, Mouse, Rabbit, Rat, Sheep
Predicted Reactivity: Chicken (at least 90% immunogen sequence identity). Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for BRS3. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
bombesin receptor subtype-3
NCBI Official Synonym Full Names
bombesin-like receptor 3
NCBI Official Symbol
BRS3
NCBI Official Synonym Symbols
BB3
UniProt Protein Name
Bombesin receptor subtype-3
Protein Family
UniProt Gene Name
BRS3
UniProt Synonym Gene Names
BRS-3
UniProt Entry Name
BRS3_HUMAN
NCBI Protein Information
bombesin receptor subtype-3; BRS-3; G-protein coupled receptor; bombesin receptor subtype 3

NCBI Summary for BRS3

The protein encoded by this gene is a G protein-coupled membrane receptor that binds bombesin-like peptides. This binding results in activation of a phosphatidylinositol-calcium second messenger system, with physiological effects including regulation of metabolic rate, glucose metabolism, and hypertension. [provided by RefSeq, Sep 2011]
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UniProt Comments for BRS3

BRS3: Role in sperm cell division, maturation, or function. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Belongs to the G-protein coupled receptor 1 family.

Protein type: GPCR, family 1; Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCR

Chromosomal Location of Human Ortholog: Xq26.3

Cellular Component: neuron projection; cell soma; plasma membrane; integral to membrane

Molecular Function: bombesin receptor activity

Biological Process: regulation of blood pressure; bombesin receptor signaling pathway; glucose metabolic process; adult feeding behavior
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-BRS3 antibody

Organs/Tissues associated with anti-BRS3 antibody

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