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GPR149 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS240091

MBS240091 is an antibody targeting GPR149. Also known as Rabbit Polyclonal to Human GPR149 / PGR10. Reactive in Gibbon, Gorilla, Human, MonkeyPredicted Reactivity: Bovine, Dog, Pig (at least 90% immunogen sequence identity). Host: Rabbit. The G… More details

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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
GPR149 / PGR10, Polyclonal Antibody
Full Product Name
Rabbit Polyclonal to Human GPR149 / PGR10
Product Gene Name
Product Synonym Gene Name
PGR10
Product Synonym Names
Anti-GPR149 / PGR10 Antibody (C-Terminus) IHC-plus; GPR149; PGR10; G protein-coupled receptor 149; IEDA; Human GPR149; PGR10
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Gibbon, Gorilla, Human, Monkey
Predicted Reactivity: Bovine, Dog, Pig (at least 90% immunogen sequence identity)
Form/Format
PBS, 0.1% sodium azide.
Purity/Purification
Immunoaffinity Purified
Concentration
1 mg/ml (lot specific)
Specificity
Human GPR149. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Preparation and Storage
Long term: -70 degree C; Short term: +4 degree C
Molecular Weight
80,984 Da
3D Structure
ModBase 3D Structure for Q86SP6
Target Species
Human
Immunogen Description
Synthetic 16 amino acid peptide from C-terminus of human GPR149. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Marmoset (100%); Bovine, Dog, Elephant, Pig (94%); Bat, Panda, Rabbit, Horse (88%).
Immunogen Type
Synthetic peptide
Immunogen
GPR149 / PGR10 antibody was raised against synthetic 16 amino acid peptide from C-terminus of human GPR149. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Marmoset (100%); Bovine, Dog, Elephant, Pig (94%); Bat, Panda, Rabbit, Horse (88%).
Antigen Modification
C-Terminus
Applications Tested/Suitable for anti-GPR149 antibody
Immunohistochemistry (IHC - Paraffin)
Application Notes for anti-GPR149 antibody
IHC-P (2.5 - 5 ug/ml)
Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary anti...

Immunohistochemistry (IHC) of anti-GPR149 antibody

Anti-GPR149 antibody IHC of human spinal cord, dorsal root ganglion. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Rabbit Anti-GPR149 Polyclonal Antibody – Cat# MBS240091

Other Notes

Small volumes of anti-GPR149 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for GPR149. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
probable G-protein coupled receptor 149
NCBI Official Synonym Full Names
G protein-coupled receptor 149
NCBI Official Symbol
GPR149
NCBI Official Synonym Symbols
IEDA; PGR10
UniProt Protein Name
Probable G-protein coupled receptor 149
UniProt Synonym Protein Names
G-protein coupled receptor PGR10
UniProt Gene Name
GPR149
UniProt Synonym Gene Names
PGR10
UniProt Entry Name
GP149_HUMAN
NCBI Protein Information
probable G-protein coupled receptor 149; G protein-coupled receptor PGR10; G-protein coupled receptor PGR10

UniProt Comments for GPR149

GPCR149: Orphan receptor. Belongs to the G-protein coupled receptor 1 family.

Protein type: GPCR, family 1; Membrane protein, integral; Receptor, GPCR; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 3q25.2

Cellular Component: neuron projection; integral to plasma membrane

Molecular Function: G-protein coupled receptor activity; neuropeptide binding

Biological Process: synaptic transmission; G-protein signaling, coupled to cyclic nucleotide second messenger; neuropeptide signaling pathway; antral ovarian follicle growth; preantral ovarian follicle growth
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Organs/Tissues associated with anti-GPR149 antibody

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >1 publications with GPR149 and Brain
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