• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

CREM/ICER Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS2401764

CREM/ICER is a bZIP transcription factor that binds to the cAMPresponsive element found in many viral and cellular promoters. It is animportant component of cAMP-mediated signal transduction during the spermatogenetic cycle, as well as other complex… More details

$650 / 0.05 mL +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
CREM/ICER, Polyclonal Antibody
Full Product Name
Anti-CREM/ICER Antibody (Internal)
Product Gene Name
Product Synonym Names
Rabbit Polyclonal (IgG) to Human CREM/ICER; CREM; CREM-2; CREM 2alpha-b protein; CREM 2beta-a protein; HCREM-2; Inducible cAMP early repressor; ICER
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human
Predicted: Mouse, Dog, Bovine, Rat, Pig
Form/Format
PBS, pH 7.3, 0.01% sodium azide, 30% glycerol.
Purity/Purification
Immunoaffinity Purified
Specificity
Recognizes endogenous levels of ICER protein.
Preparation and Storage
Store at -20 degree C.
Aliquot to avoid freeze/thaw cycles.
Molecular Weight
26,269 Da
OMIM
123812
3D Structure
ModBase 3D Structure for Q03060
Immunogen
KLH-conjugated synthetic peptide encompassing a sequence within the central region of human ICER.
Conjugation
Unconjugated
Epitope
Internal
Applications Tested/Suitable for anti-CREM/ICER antibody
Immunohistochemistry (IHC) Paraffin, Western Blot (WB)
Application Notes for anti-CREM/ICER antibody
IHC-P: 1:100
WB: 1:500-1:1000

Immunohistochemistry (IHC) of anti-CREM/ICER antibody

Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE)
Rabbit Anti-CREM/ICER Polyclonal Antibody – Cat# MBS2401764

Immunohistochemistry (WB) of anti-CREM/ICER antibody

Human Brain, Cerebellum: Formalin-Fixed, Paraffin-Embedded (FFPE)
Rabbit Anti-CREM/ICER Polyclonal Antibody, Immunohistochemistry (WB) – Cat# MBS2401764

Western Blot (WB) of anti-CREM/ICER antibody

Western blot analysis of ICER expression in HeLa (A); Raw264.7 (B) whole cell lysates.
Rabbit Anti-CREM/ICER Polyclonal Antibody, Western Blot (WB) – Cat# MBS2401764

Other Notes

Small volumes of anti-CREM/ICER antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CREM/ICER purchase

MBS2401764 is an antibody targeting CREM/ICER. Also known as Anti-CREM/ICER Antibody (Internal). Reactive in Human
Predicted: Mouse, Dog, Bovine, Rat, Pig. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for CREM/ICER. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
cAMP-responsive element modulator isoform 2
NCBI Official Synonym Full Names
cAMP responsive element modulator
NCBI Official Symbol
CREM
NCBI Official Synonym Symbols
ICER; CREM-2; hCREM-2
UniProt Protein Name
cAMP-responsive element modulator
UniProt Synonym Protein Names
Inducible cAMP early repressor; ICER
UniProt Gene Name
CREM
UniProt Synonym Gene Names
ICER
NCBI Protein Information
cAMP-responsive element modulator

NCBI Summary for CREM/ICER

This gene encodes a bZIP transcription factor that binds to the cAMP responsive element found in many viral and cellular promoters. It is an important component of cAMP-mediated signal transduction during the spermatogenetic cycle, as well as other complex processes. Alternative promoter and translation initiation site usage allows this gene to exert spatial and temporal specificity to cAMP responsiveness. Multiple alternatively spliced transcript variants encoding several different isoforms have been found for this gene, with some of them functioning as activators and some as repressors of transcription. [provided by RefSeq, Jul 2008]
Show more

UniProt Comments for CREM/ICER

Transcriptional regulator that binds the cAMP response element (CRE), a sequence present in many viral and cellular promoters. Isoforms are either transcriptional activators or repressors. Plays a role in spermatogenesis and is involved in spermatid maturation (PubMed:10373550).

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000