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PPP6C Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS240290

Protein phosphatase 6 (PPP6C) is a serine/threonine phosphatase that may function in cell cycle regulation based on its functional homology with budding yeast Sit4p and fission yeast ppe1. The phosphoprotein alpha4 has been identified as a potential… More details

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Product Overview

Product Name
PPP6C / PP6, Polyclonal Antibody
Full Product Name
Rabbit Polyclonal
Product Gene Name
Product Synonym Gene Name
PP6
Product Synonym Names
Anti-PPP6C / PP6 Antibody IHC-plus; PPP6C; PP6; PP6C; PPP6; Protein phosphatase 6; PPP6C; PP6
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Bovine, Human, Mouse, Rat
Form/Format
PBS, 0.08% sodium azide.
Purity/Purification
Purified
Concentration
1 mg/ml (lot specific)
Preparation and Storage
+4 degree C or -20 degree C, Avoid repeated freezing and thawing.
Molecular Weight
38,947 Da
OMIM
612725
3D Structure
ModBase 3D Structure for O00743
Immunogen Description
Synthetic peptide conjugated to KLH corresponding to the sequence NH2-Cys-Ala-Val-Pro-Asp-Ser-Glu-Arg-Val-Ile-Pro-Pro-Arg-Thr-Thr-Thr-Pro-Tyr-COOH.
Immunogen Type
Synthetic peptide - KLH conjugated
Immunogen
PPP6C / PP6 antibody was raised against synthetic peptide conjugated to KLH corresponding to the sequence NH2-Cys-Ala-Val-Pro-Asp-Ser-Glu-Arg-Val-Ile-Pro-Pro-Arg-Thr-Thr-Thr-Pro-Tyr-COOH.
Applications Tested/Suitable for anti-PPP6C antibody
Immunohistochemistry (IHC - Paraffin), Western Blot (WB), Immunoprecipitation (IP)
Application Notes for anti-PPP6C antibody
IHC-P (20 ug/ml), IP, WB
Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antib...

Immunohistochemistry (IHC) of anti-PPP6C antibody

Anti-PPP6C antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 20 ug/ml.
Rabbit Anti-PPP6C Polyclonal Antibody – Cat# MBS240290

Other Notes

Small volumes of anti-PPP6C antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PPP6C purchase

MBS240290 is an antibody targeting PPP6C. Also known as Rabbit Polyclonal. Reactive in Bovine, Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for PPP6C. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
serine/threonine-protein phosphatase 6 catalytic subunit isoform b
NCBI Official Synonym Full Names
protein phosphatase 6, catalytic subunit
NCBI Official Symbol
PPP6C
NCBI Official Synonym Symbols
PP6; PP6C
UniProt Protein Name
Serine/threonine-protein phosphatase 6 catalytic subunit
UniProt Gene Name
PPP6C
UniProt Synonym Gene Names
PPP6; PP6C
UniProt Entry Name
PPP6_HUMAN
NCBI Protein Information
serine/threonine-protein phosphatase 6 catalytic subunit; serine/threonine protein phosphatase catalytic subunit

NCBI Summary for PPP6C

This gene encodes the catalytic subunit of protein phosphatase, a component of a signaling pathway regulating cell cycle progression. Splice variants encoding different protein isoforms exist. The pseudogene of this gene is located on chromosome X. [provided by RefSeq, Jul 2008]

UniProt Comments for PPP6C

PPP6C: a Ser/Thr phosphatase. A functional homologue of budding yeast Sit4p and fission yeast ppe1, which are involved in cell cycle regulation.

Protein type: EC 3.1.3.16; Motility/polarity/chemotaxis; Protein phosphatase, Ser/Thr (non-receptor)

Chromosomal Location of Human Ortholog: 9q33.3

Cellular Component: cytosol

Molecular Function: protein binding; metal ion binding; protein serine/threonine phosphatase activity

Biological Process: protein amino acid dephosphorylation; G1/S transition of mitotic cell cycle
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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