• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

USP19 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS2403209

USP19 antibody is an unconjugated rabbit polyclonal antibody to USP19 from human.USP19 is a deubiquitinating enzyme that regulates the degradation of various proteins such as RNF123, which stimulates CDKN1B ubiquitin-dependent degradation and impacts cell… More details

$650 / 0.05 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
USP19, Polyclonal Antibody
Full Product Name
USP19 Rabbit anti-Human Polyclonal Antibody
Product Gene Name
anti-USP19 antibody
Product Synonym Names
PathPlus USP19 Antibody; USP19; KIAA0891; Ubiquitin thioesterase 19; Ubiquitin thiolesterase 19; Deubiquitinating enzyme 19; Ubiquitin specific protease 19; ZMYND9
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human
Form/Format
PBS, 0.1% Sodium Azide
Purity/Purification
Immunoaffinity purified
Concentration
1mg/ml (lot specific)
Preparation and Storage
Aliquot and store undiluted at -20 degree C or below for up to 1 year. Can be stored undiluted at 4 degree C for up to 1 month. Avoid freeze-thaw cycles.
OMIM
614471
3D Structure
ModBase 3D Structure for O94966
Target
Human USP19
Immunogen
LP-10984, synthetic peptide
Conjugation
Unconjugated
Family
Protease
Subfamily
Cysteine C19
Applications Tested/Suitable for anti-USP19 antibody
Immunohistochemistry-Paraffin (IHC-P), Simple Western Blot (SWB)

Western Blot (WB) of anti-USP19 antibody

USP19 Antibody-Anti-USP19 antibody (MBS2403209, 100 ug/mL) yields a specific band on capillary Western analysis (Protein Simple, WES 12-230 kDa separation module) in 250 ?g human ATG16L1 overexpression lysate.
Rabbit Anti-USP19 Polyclonal Antibody – Cat# MBS2403209

Immunohistochemistry (IHC) of anti-USP19 antibody

USP19 Antibody-Human Thyroid: Formalin-Fixed, Paraffin-Embedded (FFPE)
Rabbit Anti-USP19 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS2403209

Immunohistochemistry (IHC) of anti-USP19 antibody

USP19 Antibody-Human Tonsil: Formalin-Fixed, Paraffin-Embedded (FFPE)
Rabbit Anti-USP19 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS2403209

Immunohistochemistry (IHC) of anti-USP19 antibody

USP19 Antibody-Human Brain, Cortex: Formalin-Fixed, Paraffin-Embedded (FFPE)
Rabbit Anti-USP19 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS2403209

Immunohistochemistry (IHC) of anti-USP19 antibody

USP19 Antibody-Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE)
Rabbit Anti-USP19 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS2403209

Product References and Citations for anti-USP19 antibody

The UniProt Consortium. Nucleic Acids Res. 47: D506-515 (2019); Nucleic Acids Res. 2016 Jan 4;44(D1):D733-45, PMID:26553804; PLoS One. 2016 Jan 25;11(1):e0147515, PMID: 26808260; Mol Biol Cell. 2015 Mar 1;26(5):913-23, PMID: 25568336; Oncotarget. 2017 Jan 10; 8(2): 2197 -2208, PMID: 27517492

Other Notes

Small volumes of anti-USP19 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for USP19 purchase

MBS2403209 is an antibody targeting USP19. Also known as USP19 Rabbit anti-Human Polyclonal Antibody. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for USP19. It may not necessarily be applicable to this product.

NCBI GeneID
10869
NCBI Accession #
BAA74914.1
NCBI Related Accession #
BC014934
UniProt Primary Accession #
O94966
UniProt Protein Name
Ubiquitin carboxyl-terminal hydrolase 19
UniProt Synonym Protein Names
Deubiquitinating enzyme 19; Ubiquitin thioesterase 19; Ubiquitin-specific-processing protease 19; Zinc finger MYND domain-containing protein 9
UniProt Gene Name
USP19
UniProt Synonym Gene Names
KIAA0891; ZMYND9
UniProt Entry Name
UBP19_HUMAN

UniProt Comments for USP19

USP19: Deubiquitinating enzyme that regulates the degradation of various proteins. Deubiquitinates and prevents proteasomal degradation of RNF123 which in turn stimulates CDKN1B ubiquitin- dependent degradation thereby playing a role in cell proliferation. Involved in decreased protein synthesis in atrophying skeletal muscle. Modulates transcription of major myofibrillar proteins. Also involved in turnover of endoplasmic- reticulum-associated degradation (ERAD) substrates. Regulates the stability of BIRC2/c-IAP1 and BIRC3/c-IAP2 by preventing their ubiquitination. Required for cells to mount an appropriate response to hypoxia and rescues HIF1A from degradation in a non- catalytic manner. Plays an important role in 17 beta-estradiol (E2)-inhibited myogenesis. Decreases the levels of ubiquitinated proteins during skeletal muscle formation and acts to repress myogenesis. Exhibits a preference towards 'Lys-63'-linked Ubiquitin chains. Belongs to the peptidase C19 family. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 3.4.19.12; Ubiquitin-specific protease; Protease; Membrane protein, integral; Ubiquitin conjugating system

Chromosomal Location of Human Ortholog: 3p21.31

Cellular Component: endoplasmic reticulum membrane; integral to membrane; cytosol

Molecular Function: protein binding; metal ion binding; cysteine-type endopeptidase activity; ubiquitin-specific protease activity

Biological Process: negative regulation of skeletal muscle development; ER-associated protein catabolic process; protein deubiquitination; regulation of protein stability
Show more

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000