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MOAP1 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS240332

Apoptosis plays a major role in normal organism development, tissue homeostasis, and removal of damaged cells. Disruption of this process has been implicated in a variety of diseases such as cancer. Members of the Bcl-2 family are known to be critical… More details

$650 / 0.05 mg +1 FREE 8GB USB
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Sample Manual Insert View PDF
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Testing Data View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
MOAP1 / MAP1, Polyclonal Antibody
Full Product Name
Rabbit Polyclonal to Human MOAP1 / MAP1
Product Gene Name
Product Synonym Gene Name
MAP1
Product Synonym Names
Anti-MOAP1 / MAP1 Antibody (Internal) IHC-plus; MOAP1; MAP-1; MAP1; Modulator of apoptosis 1; Paraneoplastic antigen like 4; Paraneoplastic antigen Ma4; PNMA4; Human MOAP1; MAP1
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human, Mouse
Form/Format
PBS, 0.02% sodium azide.
Purity/Purification
Immunoaffinity Purified
Concentration
1 mg/ml (lot specific)
Specificity
15 amino acid peptide from near the center of human MAP-1
Preparation and Storage
Short term 4 degree C, long term aliquot and store at -20 degree C, avoid freeze thaw cycles. Store undiluted.
Molecular Weight
39,513 Da
OMIM
609485
3D Structure
ModBase 3D Structure for Q96BY2
Target Species
Human
Immunogen Description
Synthetic peptide from human MOAP1 / MAP1.
Immunogen Type
Synthetic peptide
Immunogen
MOAP1 / MAP1 antibody was raised against synthetic peptide from human MOAP1 / MAP1.
Antigen Modification
Internal

Product Categories/Family for anti-MOAP1 antibody

Applications Tested/Suitable for anti-MOAP1 antibody
Immunohistochemistry (IHC - Paraffin), Western Blot (WB)
Application Notes for anti-MOAP1 antibody
IHC-P (2.5 ug/ml), WB (1 ug/ml)
Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antib...

Immunohistochemistry (IHC) of anti-MOAP1 antibody

Anti-MOAP1 / MAP1 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Rabbit Anti-MOAP1 Polyclonal Antibody – Cat# MBS240332

Western Blot (WB) of anti-MOAP1 antibody

Western blot of MAP-1 in EL4 cell lysate with MAP-1 antibody (IN) at (A) 1, (B) 2, and (C) 4 ug/ml.
Rabbit Anti-MOAP1 Polyclonal Antibody, Western Blot (WB) – Cat# MBS240332

Other Notes

Small volumes of anti-MOAP1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for MOAP1 purchase

MBS240332 is an antibody targeting MOAP1. Also known as Rabbit Polyclonal to Human MOAP1 / MAP1. Reactive in Human, Mouse. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for MOAP1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
modulator of apoptosis 1
NCBI Official Synonym Full Names
modulator of apoptosis 1
NCBI Official Symbol
MOAP1
NCBI Official Synonym Symbols
MAP-1; PNMA4
UniProt Protein Name
Modulator of apoptosis 1
UniProt Synonym Protein Names
Paraneoplastic antigen Ma4
UniProt Gene Name
MOAP1
UniProt Synonym Gene Names
PNMA4; MAP-1; MAP1
UniProt Entry Name
MOAP1_HUMAN
NCBI Protein Information
modulator of apoptosis 1; MAP1; paraneoplastic antigen Ma4; paraneoplastic antigen like 4; paraneoplastic Ma antigen family member 4

NCBI Summary for MOAP1

The protein encoded by this gene was identified by its interaction with apoptosis regulator BAX protein. This protein contains a Bcl-2 homology 3 (BH3)-like motif, which is required for the association with BAX. When overexpressed, this gene has been shown to mediate caspase-dependent apoptosis. [provided by RefSeq, Jul 2008]
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UniProt Comments for MOAP1

MOAP1: Required for death receptor-dependent apoptosis. When associated with RASSF1, promotes BAX conformational change and translocation to mitochondrial membranes in response to TNF and TNFSF10 stimulation. Belongs to the PNMA family.

Chromosomal Location of Human Ortholog: 14q32

Cellular Component: mitochondrial outer membrane; mitochondrion; cytoplasm; cytosol

Molecular Function: protein binding; ubiquitin protein ligase binding

Biological Process: DNA damage response, signal transduction resulting in induction of apoptosis; induction of apoptosis via death domain receptors; positive regulation of apoptosis; protein insertion into mitochondrial membrane during induction of apoptosis
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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