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NRN1 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS240389

MBS240389 is an antibody targeting NRN1. Also known as Rabbit Polyclonal to Human NRN1 / Neuritin. Reactive in Human, Mouse. Host: Rabbit. More details

$750 / 0.05 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
NRN1 / Neuritin, Polyclonal Antibody
Full Product Name
Rabbit Polyclonal to Human NRN1 / Neuritin
Product Gene Name
Product Synonym Names
Anti-NRN1 / Neuritin Antibody (Internal) IHC-plus; NRN1; Neuritin 1; NRN; DJ380B8.2; Neuritin; Human NRN1; Neuritin
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human, Mouse
Form/Format
PBS, 0.02% sodium azide.
Purity/Purification
Immunoaffinity Purified
Concentration
1 mg/ml (lot specific)
Specificity
20 amino acid peptide from near the center of human neuritin.
Preparation and Storage
Short term 4 degree C, long term aliquot and store at -20 degree C, avoid freeze thaw cycles. Store undiluted.
Molecular Weight
15,333 Da
OMIM
607409
3D Structure
ModBase 3D Structure for Q9NPD7
Target Species
Human
Immunogen Description
Synthetic peptide from human NRN1 / Neuritin.
Immunogen Type
Synthetic peptide
Immunogen
NRN1 / Neuritin antibody was raised against synthetic peptide from human NRN1 / Neuritin.
Antigen Modification
Internal
Applications Tested/Suitable for anti-NRN1 antibody
Immunohistochemistry (IHC - Paraffin), Western Blot (WB)
Application Notes for anti-NRN1 antibody
IHC-P (10 ug/ml), WB
Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antib...

Immunohistochemistry (IHC) of anti-NRN1 antibody

Anti-Neuritin antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
Rabbit Anti-NRN1 Polyclonal Antibody – Cat# MBS240389

Immunofluorescence (IF) of anti-NRN1 antibody

Immunofluorescence of Neuritin in Mouse Heart cells with Neuritin antibody at 20 ug/ml.
Rabbit Anti-NRN1 Polyclonal Antibody, Immunofluorescence (IF) – Cat# MBS240389

Western Blot (WB) of anti-NRN1 antibody

Western blot of neuritin in Daudi cell lysate with neuritin antibody at (A) 5 and (B) 10 ug/ml.
Rabbit Anti-NRN1 Polyclonal Antibody, Western Blot (WB) – Cat# MBS240389

Other Notes

Small volumes of anti-NRN1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for NRN1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
neuritin isoform 1
NCBI Official Synonym Full Names
neuritin 1
NCBI Official Symbol
NRN1
NCBI Official Synonym Symbols
NRN; dJ380B8.2
UniProt Protein Name
Neuritin
Protein Family
UniProt Gene Name
NRN1
UniProt Synonym Gene Names
NRN
UniProt Entry Name
NRN1_HUMAN
NCBI Protein Information
neuritin

NCBI Summary for NRN1

This gene encodes a member of the neuritin family, and is expressed in postmitotic-differentiating neurons of the developmental nervous system and neuronal structures associated with plasticity in the adult. The expression of this gene can be induced by neural activity and neurotrophins. The encoded protein contains a consensus cleavage signal found in glycosylphoshatidylinositol (GPI)-anchored proteins. The encoded protein promotes neurite outgrowth and arborization, suggesting its role in promoting neuritogenesis. Overexpression of the encoded protein may be associated with astrocytoma progression. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
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UniProt Comments for NRN1

NRN1: Promotes neurite outgrowth and especially branching of neuritic processes in primary hippocampal and cortical cells. Belongs to the neuritin family.

Protein type: Membrane protein, GPI anchor

Chromosomal Location of Human Ortholog: 6p25.1

Cellular Component: plasma membrane; synapse; cell junction

Biological Process: nervous system development
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-NRN1 antibody

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