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BIRC8 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS240475

Apoptosis, or programmed cell death, is related to many diseases, such as cancer. Apoptosis is triggered by a variety of stimuli including members in the TNF family and prevented by the inhibitor of apoptosis (IAP) proteins. IAP proteins form a conserved gene… More details

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Product Overview

Product Name
BIRC8 / ILP2, Polyclonal Antibody
Full Product Name
Rabbit Polyclonal to Human BIRC8 / ILP2
Product Gene Name
Product Synonym Gene Name
ILP2
Product Synonym Names
Anti-BIRC8 / ILP2 Antibody (N-Terminus) IHC-plus; BIRC8; HILP2; ILP-2; ILP2; IAP-like protein 2; Human BIRC8; ILP2
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
PBS, 0.02% sodium azide.
Purity/Purification
Immunoaffinity Purified
Concentration
1 mg/ml (lot specific)
Specificity
synthetic peptide corresponding to amino acids near the amino terminus of human ILP-2
Preparation and Storage
Short term 4 degree C, long term aliquot and store at -20 degree C, avoid freeze thaw cycles. Store undiluted.
Molecular Weight
27,089 Da
3D Structure
ModBase 3D Structure for Q96P09
Target Species
Human
Immunogen Description
Synthetic peptide from human BIRC8 / ILP2.
Immunogen Type
Synthetic peptide
Immunogen
BIRC8 / ILP2 antibody was raised against synthetic peptide from human BIRC8 / ILP2.
Antigen Modification
N-Terminus

Product Categories/Family for anti-BIRC8 antibody

Applications Tested/Suitable for anti-BIRC8 antibody
Immunohistochemistry (IHC - Paraffin), Immunocytochemistry (ICC), Western Blot (WB)
Application Notes for anti-BIRC8 antibody
ICC, IHC-P (5 ug/ml), WB (1 - 2 ug/ml)
Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antib...

Immunohistochemistry (IHC) of anti-BIRC8 antibody

Anti-BIRC8 / ILP2 antibody IHC of human small intestine, Peyer's patch. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Rabbit Anti-BIRC8 Polyclonal Antibody – Cat# MBS240475

Immunofluorescence (IF) of anti-BIRC8 antibody

Immunofluorescence of ILP-2 in HepG2 cells with ILP-2 antibody at 20 ug/ml.
Rabbit Anti-BIRC8 Polyclonal Antibody, Immunofluorescence (IF) – Cat# MBS240475

Immunocytochemistry (ICC) of anti-BIRC8 antibody

Immunocytochemistry of ILP-2 in HepG2 cells with ILP-2 antibody at 10 ug/ml.
Rabbit Anti-BIRC8 Polyclonal Antibody, Immunocytochemistry (ICC) – Cat# MBS240475

Western Blot (WB) of anti-BIRC8 antibody

Western blot of ILP-2 expression in human HepG2 (lane 1) and MOLT4 (lane 2) cell lysates with ILP-2 antibody at 1 ug/ml.
Rabbit Anti-BIRC8 Polyclonal Antibody, Western Blot (WB) – Cat# MBS240475

Other Notes

Small volumes of anti-BIRC8 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for BIRC8 purchase

MBS240475 is an antibody targeting BIRC8. Also known as Rabbit Polyclonal to Human BIRC8 / ILP2. Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for BIRC8. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
baculoviral IAP repeat-containing protein 8
NCBI Official Synonym Full Names
baculoviral IAP repeat containing 8
NCBI Official Symbol
BIRC8
NCBI Official Synonym Symbols
ILP2; ILP-2; hILP2
UniProt Protein Name
Baculoviral IAP repeat-containing protein 8
UniProt Synonym Protein Names
Inhibitor of apoptosis-like protein 2; IAP-like protein 2; ILP-2; Testis-specific inhibitor of apoptosis
UniProt Gene Name
BIRC8
UniProt Synonym Gene Names
ILP2; IAP-like protein 2; ILP-2
UniProt Entry Name
BIRC8_HUMAN
NCBI Protein Information
baculoviral IAP repeat-containing protein 8; IAP-like protein 2; baculoviral IAP repeat-containing 8; inhibitor of apoptosis-like protein 2; testis-specific inhibitor of apoptosis

UniProt Comments for BIRC8

BIRC8: Protects against apoptosis mediated by BAX. Belongs to the IAP family.

Protein type: Ubiquitin conjugating system; Apoptosis

Chromosomal Location of Human Ortholog: -

Cellular Component: spindle microtubule; perinuclear region of cytoplasm; cytoplasm; nucleus; cytosol

Molecular Function: protease binding; zinc ion binding; caspase inhibitor activity; ubiquitin-protein ligase activity

Biological Process: neuron apoptosis; protein ubiquitination; negative regulation of neuron apoptosis; negative regulation of apoptosis
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Organs/Tissues associated with anti-BIRC8 antibody

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