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AVEN Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS240489

MBS240489 is an antibody targeting AVEN. Also known as Rabbit Polyclonal to Human AVEN / PDCD12. Reactive in Human, Mouse, Rat. Host: Rabbit. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
AVEN / PDCD12, Polyclonal Antibody
Full Product Name
Rabbit Polyclonal to Human AVEN / PDCD12
Product Gene Name
Product Synonym Gene Name
PDCD12
Product Synonym Names
Anti-AVEN / PDCD12 Antibody (C-Terminus) IHC-plus; AVEN; Cell death regulator Aven; Programmed cell death 12; PDCD12; Human AVEN; PDCD12
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
PBS, 0.02% sodium azide.
Purity/Purification
Immunoaffinity Purified
Concentration
0.5 mg/ml (lot specific)
Specificity
14 amino acid peptide from near the carboxy terminus of human Aven
Preparation and Storage
Short term 4 degree C, long term aliquot and store at -20 degree C, avoid freeze thaw cycles. Store undiluted.
Molecular Weight
38,506 Da
OMIM
605265
3D Structure
ModBase 3D Structure for Q9NQS1
Target Species
Human
Immunogen Description
Synthetic peptide from human AVEN.
Immunogen Type
Synthetic peptide
Immunogen
AVEN / PDCD12 antibody was raised against synthetic peptide from human AVEN.
Antigen Modification
C-Terminus
Applications Tested/Suitable for anti-AVEN antibody
Immunohistochemistry (IHC - Paraffin), Western Blot (WB)
Application Notes for anti-AVEN antibody
IHC-P (2.5 ug/ml), WB (0.5 - 1 ug/ml)
Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antib...

Immunohistochemistry (IHC) of anti-AVEN antibody

Anti-AVEN antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Rabbit Anti-AVEN Polyclonal Antibody – Cat# MBS240489

Immunofluorescence (IF) of anti-AVEN antibody

Immunofluorescence of AVEN in Human Spleen cells with AVEN antibody at 20 ug/ml.
Rabbit Anti-AVEN Polyclonal Antibody, Immunofluorescence (IF) – Cat# MBS240489

Western Blot (WB) of anti-AVEN antibody

Western blot of Aven in Raji cell lysate with Aven antibody at 1 ug/ml in (A) the presence and (B) the absence of blocking peptide.
Rabbit Anti-AVEN Polyclonal Antibody, Western Blot (WB) – Cat# MBS240489

Other Notes

Small volumes of anti-AVEN antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for AVEN. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
cell death regulator Aven
NCBI Official Synonym Full Names
apoptosis, caspase activation inhibitor
NCBI Official Symbol
AVEN
NCBI Official Synonym Symbols
PDCD12
UniProt Protein Name
Cell death regulator Aven
Protein Family
UniProt Gene Name
AVEN
UniProt Entry Name
AVEN_HUMAN
NCBI Protein Information
cell death regulator Aven; programmed cell death 12

UniProt Comments for AVEN

AVEN: Protects against apoptosis mediated by Apaf-1. Binds Apaf-1, BCL-2 and BAD (Bcl-xl). Highly expressed in testis, ovary, thymus, prostate, spleen, small intestine, colon, heart, skeletal muscle, liver, kidney and pancreas.

Protein type: Inhibitor; Apoptosis

Chromosomal Location of Human Ortholog: 15q13.1

Cellular Component: membrane; endomembrane system; intracellular

Molecular Function: protein binding

Biological Process: apoptosis; negative regulation of apoptosis
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-AVEN antibody

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