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POLM Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS240531

MBS240531 is an antibody targeting POLM. Also known as Rabbit Polyclonal to Human POLM / DNA Polymerase Mu. Reactive in Human. Host: Rabbit. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
POLM / DNA Polymerase Mu, Polyclonal Antibody
Full Product Name
Rabbit Polyclonal to Human POLM / DNA Polymerase Mu
Product Gene Name
Product Synonym Names
Anti-POLM / DNA Polymerase Mu Antibody (aa6-18) IHC-plus; POLM; Polmu; Polymerase (DNA directed); mu; Pol iota; Pol Mu; Tdt-N; DNA polymerase mu; Polymerase (DNA-directed); mu; Terminal transferase; Human POLM; DNA Polymerase Mu
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human
Form/Format
0.02 M potassium phosphate, 0.15 M sodium chloride, pH 7.2, 0.01% sodium azide.
Purity/Purification
Immunoaffinity Purified
Specificity
Aa 6-18 of Human POLM m (DNA polymerase mu). POLM m is a template-directed terminal deoxynucleotide transferase that shows a preferential expression in proliferating lymphoid cells.
Preparation and Storage
+4 degree C or -20 degree C, Avoid repeated freezing and thawing.
Molecular Weight
55,070 Da
OMIM
606344
3D Structure
ModBase 3D Structure for Q9NP87
Target Species
Human
Immunogen Description
Synthetic peptide from human POLM.
Immunogen Type
Synthetic peptide
Immunogen
POLM / DNA Polymerase Mu antibody was raised against synthetic peptide from human POLM.
Antigen Modification
aa6-18
Applications Tested/Suitable for anti-POLM antibody
Immunohistochemistry (IHC - Paraffin), ELISA (EIA)
Application Notes for anti-POLM antibody
ELISA, IHC-P (5 ug/ml)
Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antib...

Immunohistochemistry (IHC) of anti-POLM antibody

Anti-POLM antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Rabbit Anti-POLM Polyclonal Antibody – Cat# MBS240531

Other Notes

Small volumes of anti-POLM antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for POLM. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
DNA-directed DNA/RNA polymerase mu isoform 1
NCBI Official Synonym Full Names
polymerase (DNA directed), mu
NCBI Official Symbol
POLM
NCBI Official Synonym Symbols
Tdt-N; Pol Mu
UniProt Protein Name
DNA-directed DNA/RNA polymerase mu
UniProt Synonym Protein Names
Terminal transferase
UniProt Gene Name
POLM
UniProt Synonym Gene Names
polmu; Pol Mu
UniProt Entry Name
DPOLM_HUMAN
NCBI Protein Information
DNA-directed DNA/RNA polymerase mu; Pol iota; DNA polymerase mu; terminal transferase; polymerase (DNA-directed), mu

UniProt Comments for POLM

POLM: Gap-filling polymerase involved in repair of DNA double- strand breaks by non-homologous end joining (NHEJ). Participates in immunoglobulin (Ig) light chain gene rearrangement in V(D)J recombination. Belongs to the DNA polymerase type-X family.

Protein type: DNA repair, damage; Transferase; EC 2.7.7.7

Chromosomal Location of Human Ortholog: 7p13

Cellular Component: nucleoplasm

Molecular Function: protein binding; DNA binding; metal ion binding; DNA-directed DNA polymerase activity

Biological Process: B cell differentiation; somatic hypermutation of immunoglobulin genes; DNA repair; DNA recombination
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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