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TBC1 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS241324

MBS241324 is an antibody targeting TBC1. Also known as Rabbit Polyclonal (IgG) to Human TBC1 / TBC1D1. Reactive in Human. Host: Rabbit. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Product Name
TBC1 / TBC1D1, Polyclonal Antibody
Full Product Name
Rabbit Polyclonal (IgG) to Human TBC1 / TBC1D1
Product Gene Name
Product Synonym Gene Name
TBC1D1
Product Synonym Names
Anti-TBC1 / TBC1D1 Antibody (C-Terminus) IHC-plus; TBC1D1; TBC; TBC1; TBC1 domain family member 1; KIAA1108; Human TBC1; TBC1D1
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
PBS, 0.02% sodium azide.
Purity/Purification
Immunoaffinity Purified
Concentration
1 mg/ml (lot specific)
Specificity
a 22 amino acid peptide from near the carboxy terminus of human TBC1D1
Preparation and Storage
Short term 4 degree C, long term aliquot and store at -20 degree C, avoid freeze thaw cycles. Store undiluted.
Molecular Weight
131,378 Da
OMIM
609850
3D Structure
ModBase 3D Structure for Q86TI0
Target Species
Human
Immunogen Description
Synthetic peptide from human TBC1D1.
Immunogen Type
Synthetic peptide
Immunogen
TBC1 / TBC1D1 antibody was raised against synthetic peptide from human TBC1D1.
Antigen Modification
C-Terminus
Applications Tested/Suitable for anti-TBC1 antibody
Immunohistochemistry (IHC - Paraffin), Western Blot (WB)
Application Notes for anti-TBC1 antibody
IHC-P (5 ug/ml), WB (4 ug/ml)
Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary anti...

Immunohistochemistry (IHC) of anti-TBC1 antibody

Anti-TBC1D1 antibody IHC of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Rabbit Anti-TBC1 Polyclonal Antibody – Cat# MBS241324

Immunohistochemistry (IHC) of anti-TBC1 antibody

Anti-TBC1D1 antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Rabbit Anti-TBC1 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS241324

Western Blot (WB) of anti-TBC1 antibody

Western blot of TBC1D1 in Daudi cell lysate with TBC1D1 antibody at (A) 1, (B) 2 and (C) 4 ug/ml.
Rabbit Anti-TBC1 Polyclonal Antibody, Western Blot (WB) – Cat# MBS241324

Other Notes

Small volumes of anti-TBC1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for TBC1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
TBC1 domain family member 1 isoform 2
NCBI Official Synonym Full Names
TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1
NCBI Official Symbol
TBC1D1
NCBI Official Synonym Symbols
TBC; TBC1
UniProt Protein Name
TBC1 domain family member 1
UniProt Gene Name
TBC1D1
UniProt Synonym Gene Names
KIAA1108
UniProt Entry Name
TBCD1_HUMAN
NCBI Protein Information
TBC1 domain family member 1

NCBI Summary for TBC1

TBC1D1 is the founding member of a family of proteins sharing a 180- to 200-amino acid TBC domain presumed to have a role in regulating cell growth and differentiation. These proteins share significant homology with TRE2 (USP6; MIM 604334), yeast Bub2, and CDC16 (MIM 603461) (White et al., 2000 [PubMed 10965142]).[supplied by OMIM, Mar 2008]
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UniProt Comments for TBC1

TBC1D1: a putative GTPase activating protein for Rab family protein(s). May play a role in the cell cycle and differentiation of various tissues.

Protein type: Ubiquitin-specific protease; GAPs; GAPs, Rab

Chromosomal Location of Human Ortholog: 4p14

Cellular Component: nucleus; cytosol

Molecular Function: protein binding

Biological Process: regulation of protein localization
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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