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RHPN2 Antibody – Goat Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS241649

MBS241649 is an antibody targeting RHPN2. Also known as Goat Polyclonal to Human RHPN2. Reactive in Bat, Bovine, Gorilla, Human, Monkey, RabbitPredicted Reactivity: Mouse, Rat, Hamster, Horse (at least 90% immunogen sequence identity). Host: Goat. More details

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Product Overview

Product Name
RHPN2, Polyclonal Antibody
Full Product Name
Goat Polyclonal to Human RHPN2
Product Gene Name
Product Synonym Names
Anti-RHPN2 Antibody (Internal) IHC-plus; RHPN2; 76 kDa RhoB effector protein; GTP-Rho-binding protein 2; Rhophilin-2; p76RBE; RHOBP; Rhophilin 2; Human RHPN2
Clonality
Polyclonal
Host
Goat
Species Reactivity
Bat, Bovine, Gorilla, Human, Monkey, Rabbit
Predicted Reactivity: Mouse, Rat, Hamster, Horse (at least 90% immunogen sequence identity)
Form/Format
Tris-buffered saline, pH 7.3, 0.5% BSA, 0.02% sodium azide
Purity/Purification
Immunoaffinity Purified
Concentration
0.5 mg/ml (lot specific)
Specificity
Human RHPN2.
Preparation and Storage
Store at -20 degree C. Minimize freezing and thawing.
Molecular Weight
59,998 Da
3D Structure
ModBase 3D Structure for Q8IUC4
Target Species
Human
Immunogen Description
Synthetic peptide C-TNKNRQKSAST from an internal region of human RHPN2 (NP_149094.3). Percent identity by BLAST analysis: Human, Gorilla, Marmoset, Bat, Bovine, Elephant, Panda, Rabbit, Opossum, Platypus (100%); Mouse, Rat, Hamster, Horse (91%).
Immunogen Type
Synthetic peptide
Immunogen
RHPN2 antibody was raised against synthetic peptide C-TNKNRQKSAST from an internal region of human RHPN2 (NP_149094.3). Percent identity by BLAST analysis: Human, Gorilla, Marmoset, Bat, Bovine, Elephant, Panda, Rabbit, Opossum, Platypus (100%); Mouse, Rat, Hamster, Horse (91%); Dog (82%).
Antigen Modification
Internal
Applications Tested/Suitable for anti-RHPN2 antibody
Immunohistochemistry (IHC - Paraffin), ELISA (EIA)
Application Notes for anti-RHPN2 antibody
ELISA (1:32000), IHC-P (5 ug/ml)
Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary anti...

Immunohistochemistry (IHC) of anti-RHPN2 antibody

Anti-RHPN2 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Goat Anti-RHPN2 Polyclonal Antibody – Cat# MBS241649

Other Notes

Small volumes of anti-RHPN2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for RHPN2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
rhophilin-2
NCBI Official Synonym Full Names
rhophilin, Rho GTPase binding protein 2
NCBI Official Symbol
RHPN2
NCBI Official Synonym Symbols
RHOBP; P76RBE
UniProt Protein Name
Rhophilin-2
UniProt Synonym Protein Names
76 kDa RhoB effector protein; GTP-Rho-binding protein 2; p76RBE
Protein Family
UniProt Gene Name
RHPN2
UniProt Entry Name
RHPN2_HUMAN
NCBI Protein Information
rhophilin-2; rhophilin 2; GTP-Rho-binding protein 2; 76 kDa RhoB effector protein; rhophilin-like Rho-GTPase binding protein

NCBI Summary for RHPN2

This gene encodes a member of the rhophilin family of Ras-homologous (Rho)-GTPase binding proteins. The encoded protein binds both GTP- and GDP-bound RhoA and GTP-bound RhoB and may be involved in the organization of the actin cytoskeleton. [provided by RefSeq, Apr 2009]

UniProt Comments for RHPN2

RHPN2: Binds specifically to GTP-Rho. May function in a Rho pathway to limit stress fiber formation and/or increase the turnover of F-actin structures in the absence of high levels of RhoA activity. Belongs to the RHPN family.

Protein type: Vesicle

Chromosomal Location of Human Ortholog: 19q13.11

Cellular Component: nucleoplasm; intracellular membrane-bound organelle; perinuclear region of cytoplasm; cytoplasm

Biological Process: signal transduction
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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