Goat Anti-ARHGAP33 Polyclonal Antibody – Cat# MBS241653

Anti-ARHGAP33 / SNX26 antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.

ARHGAP33 Antibody – Goat Polyclonal

Name: ARHGAP33 Antibody; Polyclonal; Goat; MyBioSource
Brand: MyBioSource
SKU: MBS241653
Price: 625 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS241653

MBS241653 is an antibody targeting ARHGAP33. Also known as Goat Polyclonal to Human ARHGAP33 / SNX26. Reactive in Gibbon, Dog, Gorilla, Horse, Human, Monkey, MousePredicted Reactivity: Rat, Bat, Pig (at least 90% immunogen sequence identity). Host: Goat. More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Product Name

ARHGAP33 / SNX26, Polyclonal Antibody

Full Product Name

Goat Polyclonal to Human ARHGAP33 / SNX26

Product Gene Name

anti-ARHGAP33 antibody

Product Synonym Gene Name

SNX26

Product Synonym Names

Anti-ARHGAP33 / SNX26 Antibody (C-Terminus) IHC-plus; ARHGAP33; SNX26; Sorting nexin 26; TCGAP; Sorting nexin-26; NOMA-GAP; Human ARHGAP33; SNX26

Clonality

Polyclonal

Host

Goat

Species Reactivity

Gibbon, Dog, Gorilla, Horse, Human, Monkey, Mouse
Predicted Reactivity: Rat, Bat, Pig (at least 90% immunogen sequence identity)

Form/Format

Tris-buffered saline, pH 7.3, 0.5% BSA, 0.02% sodium azide

Purity/Purification

Immunoaffinity Purified

Concentration

0.5 mg/ml (lot specific)

Specificity

Human ARHGAP33 / SNX26.

Preparation and Storage

Store at -20 degree C. Minimize freezing and thawing.

Molecular Weight

26,858 Da

OMIM

614902

Target Species

Human

Immunogen Description

Synthetic peptide SWSLHSEGQTRSYC from the C-terminus of human ARHGAP33 / SNX26 (NP_443180.2). Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Dog, Panda, Horse (100%); Rat, Bat, Pig (93%).

Immunogen Type

Synthetic peptide

Immunogen

ARHGAP33 / SNX26 antibody was raised against synthetic peptide SWSLHSEGQTRSYC from the C-terminus of human ARHGAP33 / SNX26 (NP_443180.2). Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Dog, Panda, Horse (100%); Rat, Bat, Pig (93%).

Antigen Modification

C-Terminus

Applications Tested/Suitable for anti-ARHGAP33 antibody

Immunohistochemistry (IHC - Paraffin), ELISA (EIA)

Application Notes for anti-ARHGAP33 antibody

ELISA (1:8000), IHC-P (2.5 ug/ml)
Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary anti...

Other Notes

Small volumes of anti-ARHGAP33 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for ARHGAP33. It may not necessarily be applicable to this product.

NCBI GI #

23510413

NCBI GeneID

115703

NCBI Accession #

NP_443180.2

UniProt Secondary Accession #

O14552; O14560; Q6ZSP6; Q96CP3; Q9NT23

UniProt Related Accession #

O14559

GenBank Nucleotide #

NM_052948.3

NCBI Official Full Name

rho GTPase-activating protein 33 isoform 1

NCBI Official Synonym Full Names

Rho GTPase activating protein 33

NCBI Official Symbol

ARHGAP33

NCBI Official Synonym Symbols

SNX26; TCGAP; NOMA-GAP

UniProt Protein Name

Rho GTPase-activating protein 33

UniProt Synonym Protein Names

Rho-type GTPase-activating protein 33; Sorting nexin-26; Tc10/CDC42 GTPase-activating protein

Protein Family

Rho GTPase-activating protein

UniProt Gene Name

ARHGAP33

UniProt Synonym Gene Names

SNX26; TCGAP

UniProt Entry Name

RHG33_HUMAN

NCBI Protein Information

rho GTPase-activating protein 33; sorting nexin 26; sorting nexin-26; tc10/CDC42 GTPase-activating protein; rho-type GTPase-activating protein 33; neurite outgrowth multiadaptor RhoGAP protein

NCBI Summary for ARHGAP33

This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. Alternative splice variants encoding different isoforms have been identified in this gene. [provided by RefSeq, Feb 2010]

UniProt Comments for ARHGAP33

SNX26: May be involved in several stages of intracellular trafficking. Could play an important role in the regulation of glucose transport by insulin. May act as a downstream effector of RHOQ/TC10 in the regulation of insulin-stimulated glucose transport. Belongs to the PX domain-containing GAP family. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: GAPs; GAPs, Rac/Rho; Vesicle

Chromosomal Location of Human Ortholog: 19q13.12

Cellular Component: plasma membrane; cytosol

Molecular Function: protein binding; phosphoinositide binding

Biological Process: regulation of small GTPase mediated signal transduction; protein transport; small GTPase mediated signal transduction

Research Articles on ARHGAP33

1. Results show that neurite outgrowth multiadaptor RhoGAP protein, NOMA-GAP, plays an essential role downstream of NGF in promoting neurite outgrowth and extension by recruiting SHP2 and activating Cdc42.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-ARHGAP33 antibody

Products by Pathway	Pathway Diagram
Insulin Signaling Pathway antibodies	Insulin Signaling Pathway Diagram
Rho GTPase Cycle Pathway antibodies	Rho GTPase Cycle Pathway Diagram
Signal Transduction Pathway antibodies	Signal Transduction Pathway Diagram
Signaling By Rho GTPases Pathway antibodies	Signaling By Rho GTPases Pathway Diagram

Organs/Tissues associated with anti-ARHGAP33 antibody

Organ/Tissue Name	Pubmed Publications
Muscle Antibodies	>1 publications with ARHGAP33 and Muscle
Brain Antibodies	>1 publications with ARHGAP33 and Brain