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TAAR1 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS241666

TAAR1/TA1 is a Trace Amine Receptor activated by tyramine and beta-PEA. TAAR1/TA1 is likely to be involved in regulation of blood pressure, electrolyte homeostasis, and in controlling mood. An allelic variant of TAAR1/TA1 has been identified. More details

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Product Overview

Product Name
TAAR1 / TA1, Polyclonal Antibody
Full Product Name
Rabbit Polyclonal (IgG) to Human TAAR1 / TA1
Product Gene Name
anti-TAAR1 antibody
Product Synonym Gene Name
TA1
Product Synonym Names
Anti-TAAR1 / TA1 Antibody (aa225-250) IHC-plus; TAAR1; RP11-295F4.9; RTAR1; Snorf33; TRAR1; TaR-1; TAR1; TA1; Trace amine receptor 1; Human TAAR1; TA1
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Chimpanzee, Human, Monkey, Rat
Form/Format
PBS, 0.05% BSA, 0.05% sodium azide.
Purity/Purification
Protein G Purified
Concentration
1 mg/ml (lot specific)
Specificity
A portion of amino acids 225-250 of human TAAR1
Preparation and Storage
Short term 4 degree C, long term aliquot and store at -20 degree C, avoid freeze thaw cycles.
Molecular Weight
39,092 Da
OMIM
609333
3D Structure
ModBase 3D Structure for Q96RJ0
Target Species
Human
Immunogen Description
Synthetic peptide from human TAAR1.
Immunogen Type
Synthetic peptide
Immunogen
TAAR1 / TA1 antibody was raised against synthetic peptide from human TAAR1.
Antigen Modification
aa225-250

Product Categories/Family for anti-TAAR1 antibody

Family: GPCR; Subfamily: Trace amine
Applications Tested/Suitable for anti-TAAR1 antibody
Immunohistochemistry (IHC - Paraffin), Western Blot (WB)
Application Notes for anti-TAAR1 antibody
IHC-P (10 ug/ml), WB (1 - 3 ug/ml)
Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary anti...

Immunohistochemistry (IHC) of anti-TAAR1 antibody

Anti-TAAR1 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
Rabbit Anti-TAAR1 Polyclonal Antibody – Cat# MBS241666

Western Blot (WB) of anti-TAAR1 antibody

Western blot of human TAAR1 in human brain and rat brain lysate using antibody at 2 ug/ml.
Rabbit Anti-TAAR1 Polyclonal Antibody, Western Blot (WB) – Cat# MBS241666

Other Notes

Small volumes of anti-TAAR1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for TAAR1 purchase

MBS241666 is an antibody targeting TAAR1. Also known as Rabbit Polyclonal (IgG) to Human TAAR1 / TA1. Reactive in Chimpanzee, Human, Monkey, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for TAAR1. It may not necessarily be applicable to this product.

NCBI GI #
21264324
NCBI GeneID
134864
NCBI Accession #
NP_612200.1
UniProt Primary Accession #
Q96RJ0
UniProt Secondary Accession #
Q2M1W5; Q3MIH8; Q5VUQ1
UniProt Related Accession #
Q96RJ0
GenBank Nucleotide #
NM_138327.1
NCBI Official Full Name
trace amine-associated receptor 1
NCBI Official Synonym Full Names
trace amine associated receptor 1
NCBI Official Symbol
TAAR1
NCBI Official Synonym Symbols
TA1; TAR1; TRAR1
UniProt Protein Name
Trace amine-associated receptor 1
Protein Family
Trace amine-associated receptor
UniProt Gene Name
TAAR1
UniProt Synonym Gene Names
TA1; TAR1; TRAR1; TaR-1; Trace amine receptor 1
UniProt Entry Name
TAAR1_HUMAN
NCBI Protein Information
trace amine-associated receptor 1; taR-1; trace amine receptor 1

NCBI Summary for TAAR1

TAAR1 is a G protein-coupled receptor activated by trace amines. Trace amines are endogenous amine compounds that account for less than 1% of the biogenic amines in most brain regions (Bunzow et al., 2001 [PubMed 11723224]).[supplied by OMIM, Mar 2008]

UniProt Comments for TAAR1

TAAR1: Receptor for trace amines, including beta- phenylethylamine (b-PEA), p-tyramine (p-TYR), octopamine and tryptamine, with highest affinity for b-PEA and p-TYR. Unresponsive to classical biogenic amines, such as epinephrine and histamine and only partially activated by dopamine and serotonine. Trace amines are biogenic amines present in very low levels in mammalian tissues. Although some trace amines have clearly defined roles as neurotransmitters in invertebrates, the extent to which they function as true neurotransmitters in vertebrates has remained speculative. Trace amines are likely to be involved in a variety of physiological functions that have yet to be fully understood. The signal transduced by this receptor is mediated by the G(s)-class of G-proteins which activate adenylate cyclase. Belongs to the G-protein coupled receptor 1 family.

Protein type: Receptor, GPCR; GPCR, family 1; Membrane protein, integral; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 6q23.2

Cellular Component: plasma membrane; integral to membrane

Molecular Function: G-protein coupled receptor activity; trace-amine receptor activity

Biological Process: G-protein coupled receptor protein signaling pathway
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Research Articles on TAAR1

1. an increase in TAAR1 receptor expression is concomitant with lymphocyte immune activation, suggesting a possible role for TAAR1 in the generation or regulation of an immune response

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-TAAR1 antibody

 Reference Product  PubMed Publications
 ADRB2 antibody  >3 publications with TAAR1 and ADRB2
 ADRB1 antibody  >1 publications with TAAR1 and ADRB1

Pathways associated with anti-TAAR1 antibody

 Products by Pathway  Pathway Diagram
 Amine Ligand-binding Receptors Pathway antibodies  Amine Ligand-binding Receptors Pathway Diagram
 Class A/1 (Rhodopsin-like Receptors) Pathway antibodies  Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
 Defective ACTH Causes Obesity And Pro-opiomelanocortinin Deficiency (POMCD) Pathway antibodies  Defective ACTH Causes Obesity And Pro-opiomelanocortinin Deficiency (POMCD) Pathway Diagram
 Disease Pathway antibodies  Disease Pathway Diagram
 G Alpha (s) Signalling Events Pathway antibodies  G Alpha (s) Signalling Events Pathway Diagram
 GPCR Downstream Signaling Pathway antibodies  GPCR Downstream Signaling Pathway Diagram
 GPCR Ligand Binding Pathway antibodies  GPCR Ligand Binding Pathway Diagram
 Metabolic Disorders Of Biological Oxidation Enzymes Pathway antibodies  Metabolic Disorders Of Biological Oxidation Enzymes Pathway Diagram
 Neuroactive Ligand-receptor Interaction Pathway antibodies  Neuroactive Ligand-receptor Interaction Pathway Diagram
 Neuroactive Ligand-receptor Interaction Pathway antibodies  Neuroactive Ligand-receptor Interaction Pathway Diagram

Diseases associated with anti-TAAR1 antibody

 Disease Name  Pubmed Publications
 Movement Disorders Antibodies  >3 publications with TAAR1 and Movement Disorders
 Attention Deficit Disorder with Hyperactivity Antibodies  >3 publications with TAAR1 and Attention Deficit Disorder with Hyperactivity
 Catalepsy Antibodies  >2 publications with TAAR1 and Catalepsy
 Hypothermia Antibodies  >2 publications with TAAR1 and Hypothermia
 Mood Disorders Antibodies  >1 publications with TAAR1 and Mood Disorders
 Headache Antibodies  >1 publications with TAAR1 and Headache
 Nerve Degeneration Antibodies  >1 publications with TAAR1 and Nerve Degeneration
 Heart Diseases Antibodies  >1 publications with TAAR1 and Heart Diseases
 Arrhythmias, Cardiac Antibodies  >1 publications with TAAR1 and Arrhythmias, Cardiac
 Dyskinesia, Drug-Induced Antibodies  >1 publications with TAAR1 and Dyskinesia, Drug-Induced

Organs/Tissues associated with anti-TAAR1 antibody

 Organ/Tissue Name  Pubmed Publications
 Stomach Antibodies  >1 publications with TAAR1 and Stomach
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