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PACSIN2 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS241678

MBS241678 is an antibody targeting PACSIN2. Also known as Rabbit Polyclonal to Human PACSIN2. Reactive in Bovine, Chimpanzee, Chicken, Dog, Xenopus, Human, Mouse, Rat. Host: Rabbit. More details

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Product Overview

Product Name
PACSIN2, Polyclonal Antibody
Full Product Name
Rabbit Polyclonal to Human PACSIN2
Product Gene Name
Product Synonym Names
Anti-PACSIN2 Antibody (aa400-450) IHC-plus; PACSIN2; SDPII; Syndapin II; Human PACSIN2
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Bovine, Chimpanzee, Chicken, Dog, Xenopus, Human, Mouse, Rat
Form/Format
PBS, 0.2% gelatin, 0.05% sodium azide.
Purity/Purification
Immunoaffinity Purified
Concentration
0.5 mg/ml (lot specific)
Specificity
A portion of amino acids 400-450 of human PACSIN2
Preparation and Storage
Short term 4 degree C, long term aliquot and store at -20 degree C, avoid freeze thaw cycles.
Molecular Weight
51,353 Da
OMIM
604960
3D Structure
ModBase 3D Structure for Q9UNF0
Target Species
Human
Immunogen Description
Synthetic peptide from human PACSIN2.
Immunogen Type
Synthetic peptide
Immunogen
PACSIN2 antibody was raised against synthetic peptide from human PACSIN2.
Antigen Modification
aa400-450
Applications Tested/Suitable for anti-PACSIN2 antibody
Immunohistochemistry (IHC - Paraffin), Western Blot (WB)
Application Notes for anti-PACSIN2 antibody
IHC-P (10 ug/ml), WB (0.02 - 1 ug/ml)
Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary anti...

Immunohistochemistry (IHC) of anti-PACSIN2 antibody

Anti-PACSIN2 antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
Rabbit Anti-PACSIN2 Polyclonal Antibody – Cat# MBS241678

Western Blot (WB) of anti-PACSIN2 antibody

Western blot of PACSIN2 in human brain lysate in the 1) absence and 2) presence of immunizing peptide, 3) mouse brain lysate and 4) rat brain lysate using antibody at 0.05 ug/ml.
Rabbit Anti-PACSIN2 Polyclonal Antibody, Western Blot (WB) – Cat# MBS241678

Other Notes

Small volumes of anti-PACSIN2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for PACSIN2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
protein kinase C and casein kinase substrate in neurons protein 2 isoform A
NCBI Official Synonym Full Names
protein kinase C and casein kinase substrate in neurons 2
NCBI Official Symbol
PACSIN2
NCBI Official Synonym Symbols
SDPII
UniProt Protein Name
Protein kinase C and casein kinase substrate in neurons protein 2
UniProt Synonym Protein Names
Syndapin-2; Syndapin-II
UniProt Gene Name
PACSIN2
UniProt Entry Name
PACN2_HUMAN
NCBI Protein Information
protein kinase C and casein kinase substrate in neurons protein 2; syndapin2; syndapin 2; syndapin-2; syndapin II; syndapin-II; cytoplasmic phosphoprotein PACSIN2

NCBI Summary for PACSIN2

This gene is a member of the protein kinase C and casein kinase substrate in neurons family. The encoded protein is involved in linking the actin cytoskeleton with vesicle formation by regulating tubulin polymerization. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2010]
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UniProt Comments for PACSIN2

PACSIN2: May play a role in vesicle formation and transport. Belongs to the PACSIN family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Motility/polarity/chemotaxis; Adaptor/scaffold

Chromosomal Location of Human Ortholog: 22q13.2-q13.33

Cellular Component: nucleoplasm; cytoplasmic vesicle membrane; extrinsic to membrane; focal adhesion; cytoskeleton; intracellular membrane-bound organelle; recycling endosome membrane; cytoplasm; early endosome; caveola; intercellular junction; cytosol

Molecular Function: identical protein binding; protein binding; transporter activity; cytoskeletal protein binding

Biological Process: negative regulation of endocytosis; regulation of endocytosis; cell projection morphogenesis; actin cytoskeleton organization and biogenesis
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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