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FMNL2 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS241708

MBS241708 is an antibody targeting FMNL2. Also known as Rabbit Polyclonal (IgG) to Human FMNL2. Reactive in Bovine, Chimpanzee, Human, Monkey, Mouse, Rat. Host: Rabbit. More details

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Product Overview

Product Name
FMNL2, Polyclonal Antibody
Full Product Name
Rabbit Polyclonal (IgG) to Human FMNL2
Product Gene Name
Product Synonym Names
Anti-FMNL2 Antibody IHC-plus; FMNL2; Formin-like protein 2; FHOD2; KIAA1902; Formin-like 2; Human FMNL2
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Bovine, Chimpanzee, Human, Monkey, Mouse, Rat
Form/Format
PBS, 0.05% BSA, 0.05% sodium azide.
Purity/Purification
Protein G Purified
Concentration
0.5 mg/ml (lot specific)
Specificity
A portion of amino acid 1-50 of human Formin-like protein 2
Preparation and Storage
Short term 4 degree C, long term aliquot and store at -20 degree C, avoid freeze thaw cycles.
Molecular Weight
124,107 Da
3D Structure
ModBase 3D Structure for Q96PY5
Target Species
Human
Immunogen Description
Synthetic peptide from human FMNL2.
Immunogen Type
Synthetic peptide
Immunogen
FMNL2 antibody was raised against synthetic peptide from human FMNL2.
Applications Tested/Suitable for anti-FMNL2 antibody
Immunohistochemistry (IHC - Paraffin), Western Blot (WB)
Application Notes for anti-FMNL2 antibody
IHC-P (5 - 10 ug/ml), WB (1 - 3 ug/ml)
Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary anti...

Immunohistochemistry (IHC) of anti-FMNL2 antibody

Anti-FMNL2 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
Rabbit Anti-FMNL2 Polyclonal Antibody – Cat# MBS241708

Western Blot (WB) of anti-FMNL2 antibody

Western blot of Formin-like protein 2 in whole mouse embryo body tissue lysate in the 1) absence and 2) presence of immunizing peptide using antibody at 2 ug/ml.
Rabbit Anti-FMNL2 Polyclonal Antibody, Western Blot (WB) – Cat# MBS241708

Other Notes

Small volumes of anti-FMNL2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for FMNL2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
formin-like protein 2
NCBI Official Synonym Full Names
formin-like 2
NCBI Official Symbol
FMNL2
NCBI Official Synonym Symbols
FHOD2
UniProt Protein Name
Formin-like protein 2
UniProt Synonym Protein Names
Formin homology 2 domain-containing protein 2
UniProt Gene Name
FMNL2
UniProt Synonym Gene Names
FHOD2; KIAA1902
UniProt Entry Name
FMNL2_HUMAN
NCBI Protein Information
formin-like protein 2; formin homology 2 domain containing 2; formin homology 2 domain-containing protein 2

NCBI Summary for FMNL2

This gene encodes a formin-related protein. Formin-related proteins have been implicated in morphogenesis, cytokinesis, and cell polarity. Alternatively spliced transcript variants encoding different isoforms have been described but their full-length nature has yet to be determined. [provided by RefSeq, Jul 2008]
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UniProt Comments for FMNL2

FMNL2: Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the cortical actin filament dynamics. Belongs to the formin homology family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Cytoskeletal

Chromosomal Location of Human Ortholog: 2q23.3

Cellular Component: cytoplasm

Molecular Function: Rho GTPase binding; actin binding

Biological Process: regulation of cell morphogenesis; cytoskeleton organization and biogenesis; cortical actin cytoskeleton organization and biogenesis
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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