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HAVCR1 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS241834

Hepatitis A Virus Cellular Receptor 1 (HAVCR1) is a membrane receptor for both human hepatitis A virus (HHAV) and TIMD4. HAVCR1 may be involved in the moderation of asthma and allergic diseases. The reference genome represents an allele that retains a MTTVP… More details

$650 / 0.05 mg +1 FREE 8GB USB
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Product Overview

Online Datasheet in PDF
Product Name
HAVCR1 / KIM-1, Polyclonal Antibody
Full Product Name
Rabbit Polyclonal (IgG) to Human HAVCR1 / KIM-1
Product Gene Name
Product Synonym Gene Name
KIM-1
Product Synonym Names
Anti-HAVCR1 / KIM-1 Antibody (aa200-300) IHC-plus; HAVCR1; HAVCR-1; KIM-1; Kidney injury molecule 1; KIM1; T-cell membrane protein 1; TIM1; TIMD1; TIM-1; HAVCR; TIMD-1; Human HAVCR1; KIM-1
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse
Predicted Reactivity: Gorilla, Monkey (at least 90% immunogen sequence identity)
Form/Format
PBS, 0.05% BSA, 0.05% sodium azide.
Purity/Purification
Protein G Purified
Concentration
1 mg/ml (lot specific)
Specificity
A portion of amino acids 200-300 of human HAVCR1 protein was used as the immunogen.
Preparation and Storage
Store at 4 degree C for short term applications. For long term storage, aliquot and store at -20 degree C.
Molecular Weight
38,720 Da
OMIM
606518
3D Structure
ModBase 3D Structure for Q96D42
Target Species
Human
Immunogen Description
A synthetic peptide (SPLYSYTTDGNDTVT) of human HAVCR1/TIM-1protein were used as immunogen. This sequence corresponds to amino acids (aa) 248-262 of NP_036338 and aa 84-98 of EAW61615.1. Isoforms of HAVCR1/TIM-1 have been described.
Immunogen Type
Synthetic peptide
Immunogen
HAVCR1 / KIM-1 antibody was raised against a synthetic peptide (SPLYSYTTDGNDTVT) of human HAVCR1/TIM-1protein were used as immunogen. This sequence corresponds to amino acids (aa) 248-262 of NP_036338 and aa 84-98 of EAW61615.1. Isoforms of HAVCR1/TIM-1 have been described. For example, NP_036338 is 364 aa and EAW61615.1 is 194 aa. EAW61615.1 is referred to as isoform CRA_a. Percent identity by BLAST analysis: Human, Gorilla (100%); Monkey (93%); Dog (80%).
Antigen Modification
aa200-300
Applications Tested/Suitable for anti-HAVCR1 antibody
Immunohistochemistry (IHC - Paraffin), Western Blot (WB)
Application Notes for anti-HAVCR1 antibody
IHC-P (2.5 - 5 ug/ml), WB (1 - 3 ug/ml)
Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary anti...

Immunohistochemistry (IHC) of anti-HAVCR1 antibody

Anti-TIM-1 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Rabbit Anti-HAVCR1 Polyclonal Antibody – Cat# MBS241834

Western Blot (WB) of anti-HAVCR1 antibody

Western blot of HAVCR1/TIM-1 in human brain lysate in the A) absence and B) presence of immunizing peptide, and C) mouse brain lysate.
Rabbit Anti-HAVCR1 Polyclonal Antibody, Western Blot (WB) – Cat# MBS241834

Other Notes

Small volumes of anti-HAVCR1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for HAVCR1 purchase

MBS241834 is an antibody targeting HAVCR1. Also known as Rabbit Polyclonal (IgG) to Human HAVCR1 / KIM-1. Reactive in Human, Mouse
Predicted Reactivity: Gorilla, Monkey (at least 90% immunogen sequence identity). Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for HAVCR1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
hepatitis A virus cellular receptor 1
NCBI Official Synonym Full Names
hepatitis A virus cellular receptor 1
NCBI Official Symbol
HAVCR1
NCBI Official Synonym Symbols
TIM; KIM1; TIM1; HAVCR; KIM-1; TIM-1; TIMD1; TIMD-1; HAVCR-1
UniProt Protein Name
Hepatitis A virus cellular receptor 1
UniProt Synonym Protein Names
Kidney injury molecule 1; KIM-1; T-cell immunoglobulin and mucin domain-containing protein 1; TIMD-1; T-cell immunoglobulin mucin receptor 1; TIM; TIM-1; T-cell membrane protein 1
UniProt Gene Name
HAVCR1
UniProt Synonym Gene Names
KIM1; TIM1; TIMD1; HAVcr-1; KIM-1; TIMD-1; TIM; TIM-1
UniProt Entry Name
HAVR1_HUMAN
NCBI Protein Information
hepatitis A virus cellular receptor 1; kidney injury molecule 1; T-cell membrane protein 1; T-cell immunoglobulin mucin receptor 1; T-cell immunoglobulin mucin family member 1; T cell immunoglobin domain and mucin domain protein 1

NCBI Summary for HAVCR1

The protein encoded by this gene is a membrane receptor for both human hepatitis A virus (HHAV) and TIMD4. The encoded protein may be involved in the moderation of asthma and allergic diseases. The reference genome represents an allele that retains a MTTVP amino acid segment that confers protection against atopy in HHAV seropositive individuals. Three transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Mar 2010]
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UniProt Comments for HAVCR1

TIM-1: May play a role in T-helper cell development and the regulation of asthma and allergic diseases. Receptor for TIMD4. In case of human hepatitis A virus (HHAV) infection, functions as a cell-surface receptor for the virus. May play a role in kidney injury and repair. Belongs to the immunoglobulin superfamily. TIM family.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 5q33.2

Cellular Component: integral to membrane

Molecular Function: viral receptor activity

Biological Process: entry of virus into host cell

Disease: Ige Responsiveness, Atopic
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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