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CARD6 Antibody – Goat Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS241951

MBS241951 is an antibody targeting CARD6. Also known as Goat Polyclonal to Human CARD6. Reactive in Gibbon, Human, MonkeyPredicted Reactivity: Gorilla (at least 90% immunogen sequence identity). Host: Goat. More details

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Product Overview

Product Name
CARD6, Polyclonal Antibody
Full Product Name
Goat Polyclonal to Human CARD6
Product Gene Name
Product Synonym Names
Anti-CARD6 Antibody (N-Terminus) IHC-plus; CARD6; CINCIN1; Human CARD6
Clonality
Polyclonal
Host
Goat
Species Reactivity
Gibbon, Human, Monkey
Predicted Reactivity: Gorilla (at least 90% immunogen sequence identity)
Form/Format
Tris-buffered saline, pH 7.3, 0.5% BSA, 0.02% sodium azide
Purity/Purification
Immunoaffinity Purified
Concentration
0.5 mg/ml (lot specific)
Specificity
Human CARD6.
Preparation and Storage
Store at -20 degree C. Minimize freezing and thawing.
Molecular Weight
116,468 Da
OMIM
609986
3D Structure
ModBase 3D Structure for Q9BX69
Target Species
Human
Immunogen Description
Synthetic peptide ATESTPSEIIERER-C from the N-terminus of human CARD6 (NP_115976.2). Percent identity by BLAST analysis: Human, Gibbon, Monkey, Marmoset (100%); Gorilla (93%).
Immunogen Type
Synthetic peptide
Immunogen
CARD6 antibody was raised against synthetic peptide ATESTPSEIIERER-C from the N-terminus of human CARD6 (NP_115976.2). Percent identity by BLAST analysis: Human, Gibbon, Monkey, Marmoset (100%); Gorilla (93%).
Antigen Modification
N-Terminus
Applications Tested/Suitable for anti-CARD6 antibody
Immunohistochemistry (IHC - Paraffin), ELISA (EIA)
Application Notes for anti-CARD6 antibody
ELISA (1:32000), IHC-P (5 ug/ml)
Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary anti...

Immunohistochemistry (IHC) of anti-CARD6 antibody

Anti-CARD6 antibody IHC of human pancreas. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Goat Anti-CARD6 Polyclonal Antibody – Cat# MBS241951

Other Notes

Small volumes of anti-CARD6 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for CARD6. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
caspase recruitment domain-containing protein 6
NCBI Official Synonym Full Names
caspase recruitment domain family, member 6
NCBI Official Symbol
CARD6
NCBI Official Synonym Symbols
CINCIN1
UniProt Protein Name
Caspase recruitment domain-containing protein 6
UniProt Gene Name
CARD6
UniProt Entry Name
CARD6_HUMAN
NCBI Protein Information
caspase recruitment domain-containing protein 6; caspase recruitment domain protein 6; CARD-containing inhibitor of Nod1 and Cardiak-induced NF-kB activation

NCBI Summary for CARD6

This gene encodes a protein that contains a caspase recruitment domain (CARD), an antiparallel six-helical bundle that mediates homotypic protein-protein interactions. The encoded protein is a microtubule-associated protein that has been shown to interact with receptor-interacting protein kinases and positively modulate signal transduction pathways converging on activation of the inducible transcription factor NF-kB. [provided by RefSeq, Jul 2008]
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UniProt Comments for CARD6

CARD6: May be involved in apoptosis.

Protein type: Adaptor/scaffold

Chromosomal Location of Human Ortholog: 5p13.1

Biological Process: regulation of apoptosis; apoptosis

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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