Goat Anti-HMG20A Polyclonal Antibody – Cat# MBS242068

Anti-HMG20A antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.

HMG20A Antibody – Goat Polyclonal

Name: HMG20A Antibody; Polyclonal; Goat; MyBioSource
Brand: MyBioSource
SKU: MBS242068
Price: 625 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS242068

MBS242068 is an antibody targeting HMG20A. Also known as Goat Polyclonal to Human HMG20A. Reactive in Bat, Gibbon, Bovine, Chimpanzee, Dog, Gorilla, Hamster, Horse, Human, Monkey, Mouse, Orangutan, Pig, Rabbit, Rat. Host: Goat. More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Product Name

HMG20A, Polyclonal Antibody

Full Product Name

Goat Polyclonal to Human HMG20A

Product Gene Name

anti-HMG20A antibody

Product Synonym Names

Anti-HMG20A Antibody (C-Terminus) IHC-plus; HMG20A; HMGXB1; High-mobility group 20A; HMG box domain containing 1; High mobility group 20A; HMG box-containing protein 20A; HMGX1; Human HMG20A

Clonality

Polyclonal

Host

Goat

Species Reactivity

Bat, Gibbon, Bovine, Chimpanzee, Dog, Gorilla, Hamster, Horse, Human, Monkey, Mouse, Orangutan, Pig, Rabbit, Rat

Form/Format

Tris-buffered saline, pH 7.3, 0.5% BSA, 0.02% sodium azide

Purity/Purification

Immunoaffinity Purified

Concentration

0.5 mg/ml (lot specific)

Specificity

Human HMG20A.

Preparation and Storage

Store at -20 degree C. Minimize freezing and thawing.

Molecular Weight

8,671 Da

OMIM

605534

3D Structure

ModBase 3D Structure for Q9NP66

Target Species

Human

Immunogen Description

Synthetic peptide C-ATVREVVNRLDR from the C-terminus of human HMG20A (NP_060670.1).

Immunogen Type

Synthetic peptide

Immunogen

HMG20A antibody was raised against synthetic peptide C-ATVREVVNRLDR from the C-terminus of human HMG20A (NP_060670.1). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Orangutan, Gibbon, Monkey, Marmoset, Tamarin, Mouse, Rat, Hamster, Panda, Dog, Bat, Bovine, Horse, Rabbit, Pig, Opossum, Platypus (100%); Elephant (92%); Turkey, Chicken, Stickleback, Zebrafish (83%).

Antigen Modification

C-Terminus

Applications Tested/Suitable for anti-HMG20A antibody

Immunohistochemistry (IHC - Paraffin), ELISA (EIA)

Application Notes for anti-HMG20A antibody

ELISA (1:32000), IHC-P (2.5 ug/ml)
Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary anti...

Other Notes

Small volumes of anti-HMG20A antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for HMG20A. It may not necessarily be applicable to this product.

NCBI GI #

8922633

NCBI GeneID

10363

NCBI Accession #

NP_060670.1

UniProt Primary Accession #

Q9NP66

UniProt Secondary Accession #

Q53G31; Q9NSF6; A6NHY3; D3DW78

UniProt Related Accession #

Q9NP66

GenBank Nucleotide #

NM_018200.2

NCBI Official Full Name

high mobility group protein 20A

NCBI Official Synonym Full Names

high mobility group 20A

NCBI Official Symbol

HMG20A

NCBI Official Synonym Symbols

HMGX1; HMGXB1

UniProt Protein Name

High mobility group protein 20A

UniProt Synonym Protein Names

HMG box-containing protein 20A; HMG domain-containing protein 1; HMG domain-containing protein HMGX1

Protein Family

High mobility group protein

UniProt Gene Name

HMG20A

UniProt Synonym Gene Names

HMGX1; HMGXB1

UniProt Entry Name

HM20A_HUMAN

NCBI Protein Information

high mobility group protein 20A; high-mobility group 20A; HMG box domain containing 1; HMG box-containing protein 20A; HMG domain-containing protein 1; HMG domain-containing protein HMGX1

UniProt Comments for HMG20A

HMG20A: Plays a role in neuronal differentiation as chromatin- associated protein. Acts as inhibitor of HMG20B. Overcomes the repressive effects of the neuronal silencer REST and induces the activation of neuronal-specific genes. Involved in the recruitment of the histone methyltransferase MLL and consequent increased methylation of histone H3 lysine 4. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Unknown function

Chromosomal Location of Human Ortholog: 15q24

Cellular Component: nucleus

Molecular Function: protein binding; DNA binding; protein heterodimerization activity; chromatin binding; transcription factor activity

Biological Process: chromatin remodeling; establishment and/or maintenance of chromatin architecture; negative regulation of neuron differentiation; transcription, DNA-dependent; regulation of transcription, DNA-dependent; negative regulation of transcription from RNA polymerase II promoter

Research Articles on HMG20A

1. ectopic expression of BRAP2 inhibits nuclear localization of HMG20A and NuMA1, and prevents nuclear envelope accumulation of SYNE2.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-HMG20A antibody

Reference Product	PubMed Publications
HDAC1 antibody	>1 publications with HMG20A and HDAC1
HDAC2 antibody	>1 publications with HMG20A and HDAC2
KDM1A antibody	>1 publications with HMG20A and KDM1A

Diseases associated with anti-HMG20A antibody

Disease Name	Pubmed Publications
Diabetes Mellitus, Type 2 Antibodies	>7 publications with HMG20A and Diabetes Mellitus, Type 2
Muscular Diseases Antibodies	>1 publications with HMG20A and Muscular Diseases
Musculoskeletal Diseases Antibodies	>1 publications with HMG20A and Musculoskeletal Diseases

Organs/Tissues associated with anti-HMG20A antibody

Organ/Tissue Name	Pubmed Publications
Nerve Antibodies	>3 publications with HMG20A and Nerve
Brain Antibodies	>3 publications with HMG20A and Brain
Muscle Antibodies	>2 publications with HMG20A and Muscle
Pancreas Antibodies	>2 publications with HMG20A and Pancreas
Lung Antibodies	>1 publications with HMG20A and Lung
Embryonic Tissue Antibodies	>1 publications with HMG20A and Embryonic Tissue
Thyroid Antibodies	>1 publications with HMG20A and Thyroid
Adrenal Gland Antibodies	>1 publications with HMG20A and Adrenal Gland
Ovary Antibodies	>1 publications with HMG20A and Ovary
Intestine Antibodies	>1 publications with HMG20A and Intestine