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TEM7 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS242184

TEM7 (tumor endothelial marker 7) was identified because it displayed elevated expression during tumor angiogenesis. It is a type 1 membrane protein containing a plexin-like domain. More details

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Product Overview

Product Name
TEM7, Polyclonal Antibody
Full Product Name
Rabbit Polyclonal (IgG) to Human TEM7
Product Gene Name
Product Synonym Gene Name
PLXDC1
Product Synonym Names
Anti-TEM7 Antibody (Internal) IHC-plus; PLXDC1; TEM3; Tumor endothelial marker 3; Tumor endothelial marker 7; TEM7; Plexin domain containing 1; Human TEM7
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
PBS, 0.02% sodium azide.
Purity/Purification
Immunoaffinity Purified
Concentration
1 mg/ml (lot specific)
Specificity
a 16 amino acid peptide from near the center of human TEM7
Preparation and Storage
Short term 4 degree C, long term aliquot and store at -20 degree C, avoid freeze thaw cycles. Store undiluted.
Molecular Weight
47,895 Da
OMIM
606826
3D Structure
ModBase 3D Structure for Q8IUK5
Target Species
Human
Immunogen Description
Synthetic peptide from human PLXDC1 / TEM7.
Immunogen Type
Synthetic peptide
Immunogen
TEM7 antibody was raised against synthetic peptide from human PLXDC1 / TEM7.
Antigen Modification
Internal
Applications Tested/Suitable for anti-TEM7 antibody
Immunohistochemistry (IHC - Paraffin), Western Blot (WB), ELISA (EIA)
Application Notes for anti-TEM7 antibody
ELISA, IHC-P (5 ug/ml), WB (0.5 - 1 ug/ml)
Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary anti...

Immunohistochemistry (IHC) of anti-TEM7 antibody

Anti-TEM7 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Rabbit Anti-TEM7 Polyclonal Antibody – Cat# MBS242184

Immunofluorescence (IF) of anti-TEM7 antibody

Immunofluorescence of TEM7 in Mouse Liver cells with TEM7 antibody at 20 ug/ml.
Rabbit Anti-TEM7 Polyclonal Antibody, Immunofluorescence (IF) – Cat# MBS242184

Western Blot (WB) of anti-TEM7 antibody

Western blot of TEM7 in rat liver tissue lysate with TEM7 antibody at (A) 0.5 and (B) 1 ug/ml.
Rabbit Anti-TEM7 Polyclonal Antibody, Western Blot (WB) – Cat# MBS242184

Other Notes

Small volumes of anti-TEM7 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for TEM7 purchase

MBS242184 is an antibody targeting TEM7. Also known as Rabbit Polyclonal (IgG) to Human TEM7. Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for TEM7. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
plexin domain-containing protein 1
NCBI Official Synonym Full Names
plexin domain containing 1
NCBI Official Symbol
PLXDC1
NCBI Official Synonym Symbols
TEM3; TEM7
UniProt Protein Name
Plexin domain-containing protein 1
UniProt Synonym Protein Names
Tumor endothelial marker 3; Tumor endothelial marker 7
UniProt Gene Name
PLXDC1
UniProt Synonym Gene Names
TEM3; TEM7
UniProt Entry Name
PLDX1_HUMAN
NCBI Protein Information
plexin domain-containing protein 1; 2410003I07Rik; tumor endothelial marker 3; tumor endothelial marker 7

UniProt Comments for TEM7

PLXDC1: Plays a critical role in endothelial cell capillary morphogenesis. Belongs to the plexin family. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: Cell surface; Membrane protein, integral

Chromosomal Location of Human Ortholog: 17q21.1

Cellular Component: extracellular space; tight junction; cell soma; cytoplasm; dendrite; integral to membrane; plasma membrane; extracellular region; intracellular; receptor complex

Molecular Function: protein binding; receptor activity

Biological Process: spinal cord development; angiogenesis
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

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