Rabbit Anti-FAM188A Polyclonal Antibody – Cat# MBS242234

Anti-FAM188A / C10orf97 antibody IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.

FAM188A Antibody – Rabbit Polyclonal

Name: FAM188A Antibody; Polyclonal; Rabbit; MyBioSource
Brand: MyBioSource
SKU: MBS242234
Price: 625 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS242234

C10ORF97 is a member of the caspase-associated recruitment domain (CARD) family of proteins that play a role in apoptosis. It is also known as CARP. More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Product Name

FAM188A / C10orf97, Polyclonal Antibody

Full Product Name

Rabbit Polyclonal (IgG) to Human FAM188A / C10orf97

Product Gene Name

anti-FAM188A antibody

Product Synonym Gene Name

C10orf97

Product Synonym Names

Anti-FAM188A / C10orf97 Antibody (aa59-76) IHC-plus; FAM188A; C10orf97; CARD-containing protein; MST126; MSTP126; My042; RP11-394I23.1; Protein CARP; Protein FAM188A; CARP; DERP5; Human FAM188A; C10orf97

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Bat, Gibbon, Bovine, Dog, Gorilla, Hamster, Horse, Human, Monkey, Mouse, Orangutan, Rabbit, Rat
Predicted Reactivity: Pig (at least 90% immunogen sequence identity)

Form/Format

PBS, 0.02% sodium azide.

Purity/Purification

Purified

Specificity

Residues 59-76 AFLLKKLLFSSEKSSWRD of human CARP protein

Preparation and Storage

+4 degree C or -20 degree C, Avoid repeated freezing and thawing.

Molecular Weight

14,942 Da

OMIM

611649

3D Structure

ModBase 3D Structure for Q9H8M7

Target Species

Human

Immunogen Description

Synthetic peptide from human FAM188A / C10orf97. Percent identity by BLAST analysis: Human, Gorilla, Orangutan, Gibbon, Monkey, Marmoset, Mouse, Rat, Hamster, Elephant, Panda, Dog, Bat, Bovine, Horse, Rabbit (100%); Pig, Opossum (94%); Platypus (83%).

Immunogen Type

Synthetic peptide

Immunogen

FAM188A / C10orf97 antibody was raised against synthetic peptide from human FAM188A / C10orf97. Percent identity by BLAST analysis: Human, Gorilla, Orangutan, Gibbon, Monkey, Marmoset, Mouse, Rat, Hamster, Elephant, Panda, Dog, Bat, Bovine, Horse, Rabbit (100%); Pig, Opossum (94%); Platypus (83%).

Antigen Modification

aa59-76

Applications Tested/Suitable for anti-FAM188A antibody

Immunohistochemistry (IHC - Paraffin), Western Blot (WB), ELISA (EIA)

Application Notes for anti-FAM188A antibody

ELISA, IHC-P (2.5 ug/ml), WB (1:500 - 1:1000)
Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary anti...

Other Notes

Small volumes of anti-FAM188A antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for FAM188A purchase

MBS242234 is an antibody targeting FAM188A. Also known as Rabbit Polyclonal (IgG) to Human FAM188A / C10orf97. Reactive in Bat, Gibbon, Bovine, Dog, Gorilla, Hamster, Horse, Human, Monkey, Mouse, Orangutan, Rabbit, Rat
Predicted Reactivity: Pig (at least 90% immunogen sequence identity). Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for FAM188A. It may not necessarily be applicable to this product.

NCBI GI #

13376431

NCBI GeneID

80013

NCBI Accession #

NP_079224.1

UniProt Primary Accession #

Q9H8M7

UniProt Secondary Accession #

Q5SZ68; Q5SZ69; Q5SZ70; Q6IA40; Q6P7P0; Q7Z2S1; Q8WUF1; Q9H3I4

UniProt Related Accession #

Q9H8M7

GenBank Nucleotide #

NM_024948.2

NCBI Official Full Name

protein FAM188A

NCBI Official Synonym Full Names

family with sequence similarity 188, member A

NCBI Official Symbol

FAM188A

NCBI Official Synonym Symbols

CARP; DERP5; my042; MST126; MSTP126; C10orf97

UniProt Protein Name

Protein FAM188A

UniProt Synonym Protein Names

Dermal papilla-derived protein 5; Protein CARP

Protein Family

Ubiquitin carboxyl-terminal hydrolase

UniProt Gene Name

FAM188A

UniProt Synonym Gene Names

C10orf97; CARP; DERP5

UniProt Entry Name

F188A_HUMAN

NCBI Protein Information

protein FAM188A; CARD-containing protein; dermal papilla-derived protein 5; caspase recruitment domain containing pro-apoptotic protein

NCBI Summary for FAM188A

C10ORF97 is a member of the caspase-associated recruitment domain (CARD) family of proteins that play a role in apoptosis (Liu et al., 2002 [PubMed 12054670]).[supplied by OMIM, Mar 2008]

UniProt Comments for FAM188A

FAM188A: May have pro-apoptotic function. Overexpression significantly inhibits cell proliferation in several tumor cell lines. Belongs to the FAM188 family. 2 isoforms of the human protein are produced by alternative splicing.

Chromosomal Location of Human Ortholog: 10p13

Cellular Component: nucleoplasm; nuclear membrane

Molecular Function: protein binding

Biological Process: apoptosis

Research Articles on FAM188A

1. results indicated that C10ORF97 functions as a novel tumor suppressor by modulating several key G(1)/S-regulatory proteins by interacting with JAB1

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Organs/Tissues associated with anti-FAM188A antibody

Organ/Tissue Name	Pubmed Publications
Lung Antibodies	>1 publications with FAM188A and Lung