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BPOZ Antibody – Goat Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS242322

MBS242322 is an antibody targeting BPOZ. Also known as Goat Polyclonal to Human BPOZ / ABTB1. Reactive in Dog, Gorilla, Hamster, Horse, Human, Monkey, MousePredicted Reactivity: Gibbon, Rat, Bat (at least 90% immunogen sequence identity). Host: Goat. More details

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Product Overview

Product Name
BPOZ / ABTB1, Polyclonal Antibody
Full Product Name
Goat Polyclonal to Human BPOZ / ABTB1
Product Gene Name
Product Synonym Gene Name
ABTB1
Product Synonym Names
Anti-BPOZ / ABTB1 Antibody (C-Terminus) IHC-plus; ABTB1; BPOZ; BTB3; EF1ABP; PP2259; BTBD21; Human BPOZ; ABTB1
Clonality
Polyclonal
Host
Goat
Species Reactivity
Dog, Gorilla, Hamster, Horse, Human, Monkey, Mouse
Predicted Reactivity: Gibbon, Rat, Bat (at least 90% immunogen sequence identity)
Form/Format
Tris-buffered saline, pH 7.3, 0.5% BSA, 0.02% sodium azide
Purity/Purification
Immunoaffinity Purified
Concentration
0.5 mg/ml (lot specific)
Specificity
Human ABTB1 / BPOZ. This antibody is expected to recognise all reported isoforms (NP_115937.1; NP_742024.1; NP_742025.1).
Preparation and Storage
Store at -20 degree C. Minimize freezing and thawing.
Molecular Weight
44,428 Da
OMIM
608308
3D Structure
ModBase 3D Structure for Q969K4
Target Species
Human
Immunogen Description
Synthetic peptide RALEDLLVSIGLDC from the C-terminus of human ABTB1 / BPOZ (NP_115937.1; NP_742024.1; NP_742025.1). Percent identity by BLAST analysis: Human, Gorilla, Monkey, Marmoset, Mouse, Hamster, Panda, Dog, Horse (100%); Gibbon, Rat, Bat (93%).
Immunogen Type
Synthetic peptide
Immunogen
BPOZ / ABTB1 antibody was raised against synthetic peptide RALEDLLVSIGLDC from the C-terminus of human ABTB1 / BPOZ (NP_115937.1; NP_742024.1; NP_742025.1). Percent identity by BLAST analysis: Human, Gorilla, Monkey, Marmoset, Mouse, Hamster, Panda, Dog, Horse (100%); Gibbon, Rat, Bat (93%); Elephant, Bovine (86%).
Antigen Modification
C-Terminus
Applications Tested/Suitable for anti-BPOZ antibody
Immunohistochemistry (IHC - Paraffin), Western Blot (WB), ELISA (EIA)
Application Notes for anti-BPOZ antibody
ELISA (1:32000), IHC-P (3.75 ug/ml), WB (1:32000, 1 - 3 ug/ml)
Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary anti...

Immunohistochemistry (IHC) of anti-BPOZ antibody

Anti-ABTB1 / BPOZ antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 75 ug/ml.
Goat Anti-BPOZ Polyclonal Antibody – Cat# MBS242322

Immunohistochemistry (IHC) of anti-BPOZ antibody

Anti-ABTB1 / BPOZ antibody IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 75 ug/ml.
Goat Anti-BPOZ Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS242322

Western Blot (WB) of anti-BPOZ antibody

Antibody staining (1 ug/ml) of Human Heart lysate (RIPA buffer, 35 ug total protein per lane). Primary incubated for 1 hour. Detected by Western blot of chemiluminescence.
Goat Anti-BPOZ Polyclonal Antibody, Western Blot (WB) – Cat# MBS242322

Other Notes

Small volumes of anti-BPOZ antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for BPOZ. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
ankyrin repeat and BTB/POZ domain-containing protein 1 isoform 1
NCBI Official Synonym Full Names
ankyrin repeat and BTB (POZ) domain containing 1
NCBI Official Symbol
ABTB1
NCBI Official Synonym Symbols
BPOZ; BTB3; BTBD21; EF1ABP; PP2259
UniProt Protein Name
Ankyrin repeat and BTB/POZ domain-containing protein 1
UniProt Synonym Protein Names
Elongation factor 1A-binding protein
UniProt Gene Name
ABTB1
UniProt Entry Name
ABTB1_HUMAN
NCBI Protein Information
ankyrin repeat and BTB/POZ domain-containing protein 1; ABTB1; elongation factor 1A-binding protein

NCBI Summary for BPOZ

This gene encodes a protein with an ankyrin repeat region and two BTB/POZ domains, which are thought to be involved in protein-protein interactions. Expression of this gene is activated by the phosphatase and tensin homolog, a tumor suppressor. Alternate splicing results in three transcript variants. [provided by RefSeq, Mar 2010]
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UniProt Comments for BPOZ

ABTB1: May act as a mediator of the PTEN growth-suppressive signaling pathway. May play a role in developmental processes. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: Translation; RNA-binding

Chromosomal Location of Human Ortholog: 3q21

Cellular Component: cytoplasm; nucleolus; plasma membrane

Molecular Function: translation elongation factor activity

Biological Process: translational elongation
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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