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ZIC5 Antibody – Goat Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS242375

This gene encodes a member of the ZIC family of C2H2-type zinc finger proteins. Members of this family are important during development, and have been associated X-linked visceral heterotaxy and holoprosencephaly type 5. This gene is closely linked to a gene… More details

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Sample Manual Insert View PDF
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Testing Data View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
ZIC5, Polyclonal Antibody
Full Product Name
Goat Polyclonal to Human ZIC5
Product Gene Name
Product Synonym Names
Anti-ZIC5 Antibody (C-Terminus) IHC-plus; ZIC5; Zic family member 5; Zinc finger protein ZIC 5; Zinc family member 5 protein; Human ZIC5
Clonality
Polyclonal
Host
Goat
Species Reactivity
Gibbon, Gorilla, Human, Monkey
Predicted Reactivity: Hamster, Rabbit (at least 90% immunogen sequence identity)
Form/Format
Tris-buffered saline, pH 7.3, 0.5% BSA, 0.02% sodium azide
Purity/Purification
Immunoaffinity Purified
Concentration
0.5 mg/ml (lot specific)
Specificity
Human ZIC5.
Preparation and Storage
Store at -20 degree C. Minimize freezing and thawing.
Molecular Weight
68,448 Da
3D Structure
ModBase 3D Structure for Q96T25
Usage Not Recommended
Western Blot (WB)
Target Species
Human
Immunogen Description
Synthetic peptide C-EIYGNPEVVRTIH from the C-terminus of human ZIC5 (NP_149123.2). Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset (100%); Hamster, Elephant, Rabbit (92%); Mouse, Rat, Dog (85%).
Immunogen Type
Synthetic peptide
Immunogen
ZIC5 antibody was raised against synthetic peptide C-EIYGNPEVVRTIH from the C-terminus of human ZIC5 (NP_149123.2). Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset (100%); Hamster, Elephant, Rabbit (92%); Mouse, Rat, Dog (85%).
Antigen Modification
C-Terminus

Product Categories/Family for anti-ZIC5 antibody

Applications Tested/Suitable for anti-ZIC5 antibody
Immunohistochemistry (IHC - Paraffin), ELISA (EIA)
Application Notes for anti-ZIC5 antibody
ELISA (1:128000), IHC-P (3.75 ug/ml)
Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary anti...

Immunohistochemistry (IHC) of anti-ZIC5 antibody

Anti-ZIC5 antibody IHC of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 3.75 ug/ml.
Goat Anti-ZIC5 Polyclonal Antibody – Cat# MBS242375

Immunohistochemistry (IHC) of anti-ZIC5 antibody

Anti-ZIC5 antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 3.75 ug/ml.
Goat Anti-ZIC5 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS242375

Immunohistochemistry (IHC) of anti-ZIC5 antibody

Anti-ZIC5 antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 3.75 ug/ml.
Goat Anti-ZIC5 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS242375

Other Notes

Small volumes of anti-ZIC5 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ZIC5 purchase

MBS242375 is an antibody targeting ZIC5. Also known as Goat Polyclonal to Human ZIC5. Reactive in Gibbon, Gorilla, Human, Monkey
Predicted Reactivity: Hamster, Rabbit (at least 90% immunogen sequence identity). Host: Goat.

Additional Details

NCBI/Uniprot data below describe general gene information for ZIC5. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
zinc finger protein ZIC 5
NCBI Official Synonym Full Names
Zic family member 5
NCBI Official Symbol
ZIC5
UniProt Protein Name
Zinc finger protein ZIC 5
UniProt Synonym Protein Names
Zinc finger protein of the cerebellum 5
Protein Family
UniProt Gene Name
ZIC5
UniProt Entry Name
ZIC5_HUMAN
NCBI Protein Information
zinc finger protein ZIC 5; zinc family member 5 protein; zinc finger protein of the cerebellum 5; Zic family member 5 (odd-paired homolog, Drosophila)

UniProt Comments for ZIC5

ZIC5: Essential for neural crest development, converting cells from an epidermal fate to a neural crest cell fate. Binds to DNA. Belongs to the GLI C2H2-type zinc-finger protein family.

Protein type: Motility/polarity/chemotaxis; C2H2-type zinc finger protein

Chromosomal Location of Human Ortholog: 13q32.3

Cellular Component: nucleus

Molecular Function: DNA binding; metal ion binding; transcription factor activity

Biological Process: regulation of transcription, DNA-dependent; neural tube closure; forebrain development; cell differentiation
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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