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CASZ1 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS242378

MBS242378 is an antibody targeting CASZ1. Also known as Rabbit Polyclonal to Human CASZ1. Reactive in Bovine, Chimpanzee, Human, Mouse, Rat. Host: Rabbit. More details

$715 / 0.05 mg +1 FREE 8GB USB
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Sample Manual Insert View PDF
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Testing Data View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
CASZ1, Polyclonal Antibody
Full Product Name
Rabbit Polyclonal to Human CASZ1
Product Gene Name
Product Synonym Names
Anti-CASZ1 Antibody (N-Terminus) IHC-plus; CASZ1; Castor-related protein; CAS11; Castor; Castor homolog 1; zinc finger; CST; DJ734G22.1; Zinc finger protein 693; SRG; ZNF693; Castor zinc finger 1; Survival-related; Human CASZ1
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Bovine, Chimpanzee, Human, Mouse, Rat
Form/Format
0.02 M potassium phosphate, 0.15 M sodium chloride, pH 7.2.
Purity/Purification
Immunoaffinity Purified
Concentration
1 mg/ml (lot specific)
Specificity
human Cas5 protein. A BLAST analysis was used to suggest cross reactivity with Cas5 from mouse, chimpanzee, bovine, and rat based on 100% homology with the immunizing sequence. Expect cross reactivity with multiple isoforms of this protein. Cross reactivity with Cas5 from other sources has not been determined.
Preparation and Storage
+4 degree C or -20 degree C, Avoid repeated freezing and thawing.
Molecular Weight
124,788 Da
OMIM
609895
3D Structure
ModBase 3D Structure for Q86V15
Target Species
Human
Immunogen Description
Synthetic peptide corresponding to region near the amino terminal end of human Cas5 protein according to accession number CAI22571.
Immunogen Type
Synthetic peptide
Immunogen
CASZ1 antibody was raised against synthetic peptide corresponding to region near the amino terminal end of human Cas5 protein according to accession number CAI22571.
Antigen Modification
N-Terminus
Applications Tested/Suitable for anti-CASZ1 antibody
Immunohistochemistry (IHC - Paraffin), Western Blot (WB), ELISA (EIA)
Application Notes for anti-CASZ1 antibody
ELISA (1:25000 - 1:100000), IHC-P (5 ug/ml), WB (1:1000 - 1:3000)
Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary anti...

Immunohistochemistry (IHC) of anti-CASZ1 antibody

Anti-CASZ1 antibody IHC of human lung. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Rabbit Anti-CASZ1 Polyclonal Antibody – Cat# MBS242378

Western Blot (WB) of anti-CASZ1 antibody

Anti-hCas5 Antibody - Western Blot. Western blot of affinity purified anti-hCas5 antibody shows detection of a band ~125 kD in size corresponding to hCas5 (arrowhead). Lane 1 contains a lysate from AS cells transfected with empty vector. Lane 2 contains lysate from AS cells transfected with hCas5 (predicted MW 125 kD). Lane 3 contains lysate from BE2 cells that have been shown to contain a high level of hCas mRNA (as tested by Northern blot). Lane 4 contains lysate from human muscle tissue that also shows high levels of hCas mRNA. Specific band reactivity is effectively competed when the antibody is pre-incubated with the immunizing peptide (data not shown). Personal Communication. Carol Thiele, NCI, Bethesda, MD.
Rabbit Anti-CASZ1 Polyclonal Antibody, Western Blot (WB) – Cat# MBS242378

Other Notes

Small volumes of anti-CASZ1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for CASZ1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
zinc finger protein castor homolog 1 isoform b
NCBI Official Synonym Full Names
castor zinc finger 1
NCBI Official Symbol
CASZ1
NCBI Official Synonym Symbols
CST; SRG; CAS11; ZNF693; dJ734G22.1
UniProt Protein Name
Zinc finger protein castor homolog 1
UniProt Synonym Protein Names
Castor-related protein; Putative survival-related protein; Zinc finger protein 693
UniProt Gene Name
CASZ1
UniProt Synonym Gene Names
CST; SRG; ZNF693
UniProt Entry Name
CASZ1_HUMAN
NCBI Protein Information
zinc finger protein castor homolog 1; survival-related; castor-related protein; zinc finger protein 693; castor homolog 1, zinc finger

NCBI Summary for CASZ1

The protein encoded by this gene is a zinc finger transcription factor. The encoded protein may function as a tumor suppressor, and single nucleotide polymorphisms in this gene are associated with blood pressure variation. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Jul 2012]
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UniProt Comments for CASZ1

CASZ1: Probable transcription factor. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Motility/polarity/chemotaxis; C2H2-type zinc finger protein; Transcription factor

Chromosomal Location of Human Ortholog: 1p36.22

Cellular Component: nucleoplasm; intracellular membrane-bound organelle; cytoplasm

Molecular Function: DNA binding; metal ion binding

Biological Process: transcription, DNA-dependent; regulation of transcription, DNA-dependent; multicellular organismal development
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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