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PVALB Antibody – Goat Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS242380

The protein encoded by this gene is a high affinity calcium ion-binding protein that is structurally and functionally similar to calmodulin and troponin C. The encoded protein is thought to be involved in muscle relaxation. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
PVALB / Parvalbumin, Polyclonal Antibody
Full Product Name
Goat Polyclonal to Human PVALB / Parvalbumin
Product Gene Name
Product Synonym Names
Anti-PVALB / Parvalbumin Antibody (C-Terminus) IHC-plus; PVALB; D22S749; Parvalbumin; Parvalbumin alpha; Human PVALB; Parvalbumin
Clonality
Polyclonal
Host
Goat
Species Reactivity
Gibbon, Gorilla, Human, Monkey
Predicted Reactivity: Mouse, Rat, Bovine, Horse, Pig, Xenopus (at least 90% immunogen sequence identity)
Form/Format
Tris-buffered saline, pH 7.3, 0.5% BSA, 0.02% sodium azide
Purity/Purification
Immunoaffinity Purified
Concentration
0.5 mg/ml (lot specific)
Specificity
Human PVALB / Parvalbumin.
Preparation and Storage
Store at -20 degree C. Minimize freezing and thawing.
Molecular Weight
12,059 Da
OMIM
168890
3D Structure
ModBase 3D Structure for P20472
Target Species
Human
Immunogen Description
Synthetic peptide C-GVDEFSTLVAES from the C-terminus of human PVALB / Parvalbumin (NP_002845.1). Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset (100%); Mouse, Rat, Bovine, Horse, Pig, Lizard, Xenopus (92%).
Immunogen Type
Synthetic peptide
Immunogen
PVALB / Parvalbumin antibody was raised against synthetic peptide C-GVDEFSTLVAES from the C-terminus of human PVALB / Parvalbumin (NP_002845.1). Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset (100%); Mouse, Rat, Bovine, Horse, Pig, Lizard, Xenopus (92%); Rabbit, Platypus (83%).
Antigen Modification
C-Terminus
Applications Tested/Suitable for anti-PVALB antibody
Immunohistochemistry (IHC - Paraffin), Western Blot (WB), ELISA (EIA)
Application Notes for anti-PVALB antibody
ELISA (1:32000), IHC-P (2.5 ug/ml), WB (1:32000, 0.1 - 0.3 ug/ml)
Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary anti...

Immunohistochemistry (IHC) of anti-PVALB antibody

Anti-PVALB / Parvalbumin antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 2.5 ug/ml.
Goat Anti-PVALB Polyclonal Antibody – Cat# MBS242380

Western Blot (WB) of anti-PVALB antibody

Antibody (0.1 ug/ml) staining of Human Brain lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Goat Anti-PVALB Polyclonal Antibody, Western Blot (WB) – Cat# MBS242380

Other Notes

Small volumes of anti-PVALB antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PVALB purchase

MBS242380 is an antibody targeting PVALB. Also known as Goat Polyclonal to Human PVALB / Parvalbumin. Reactive in Gibbon, Gorilla, Human, Monkey
Predicted Reactivity: Mouse, Rat, Bovine, Horse, Pig, Xenopus (at least 90% immunogen sequence identity). Host: Goat.

Additional Details

NCBI/Uniprot data below describe general gene information for PVALB. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
parvalbumin alpha
NCBI Official Synonym Full Names
parvalbumin
NCBI Official Symbol
PVALB
NCBI Official Synonym Symbols
D22S749
UniProt Protein Name
Parvalbumin alpha
Protein Family
UniProt Gene Name
PVALB
UniProt Entry Name
PRVA_HUMAN
NCBI Protein Information
parvalbumin alpha

UniProt Comments for PVALB

PVA: In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions. Belongs to the parvalbumin family.

Chromosomal Location of Human Ortholog: 22q13.1

Cellular Component: protein complex; cell soma; axon; cytoplasm; nucleus

Molecular Function: protein homodimerization activity; protein heterodimerization activity; calcium ion binding

Biological Process: cytosolic calcium ion homeostasis
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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