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DREG Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS242393

GPR126 is an Orphan-B GPCR with an unknown ligand. This may be a very large gene with alternatively spliced transcripts. More details

$630 / 0.05 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
DREG / GPR126, Polyclonal Antibody
Full Product Name
Rabbit Polyclonal to Human DREG / GPR126
Product Gene Name
Product Synonym Gene Name
GPR126
Product Synonym Names
Anti-DREG / GPR126 Antibody (N-Terminus) IHC-plus; GPR126; APG1; G-protein coupled receptor 126; PS1TP2; VIGR; DREG; G protein-coupled receptor 126; Human DREG; GPR126
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Gibbon, Gorilla, Human, Mouse
Predicted Reactivity: Monkey, Rat, Bat, Bovine, Dog, Horse, Pig, Rabbit (at least 90% immunogen sequence identity)
Form/Format
PBS, 0.1% sodium azide.
Purity/Purification
Immunoaffinity Purified
Concentration
1 mg/ml (lot specific)
Specificity
Human GPR126. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except GPR64 (50%).
Preparation and Storage
Long term: -70 degree C; Short term: +4 degree C
Molecular Weight
136,878 Da
OMIM
phenotype 612243
3D Structure
ModBase 3D Structure for Q86SQ4
Target Species
Human
Immunogen Description
Synthetic 20 amino acid peptide from N-Terminus of human GPR126. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Mouse (100%); Marmoset, Rat, Bovine, Dog, Panda, Rabbit, Pig (95%); Bat, Elephant, Horse (90%).
Immunogen Type
Synthetic peptide
Immunogen
DREG / GPR126 antibody was raised against synthetic 20 amino acid peptide from N-Terminus of human GPR126. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Mouse (100%); Marmoset, Rat, Bovine, Dog, Panda, Rabbit, Pig (95%); Bat, Elephant, Horse (90%); Opossum, Platypus (80%).
Antigen Modification
N-Terminus
Applications Tested/Suitable for anti-DREG antibody
Immunohistochemistry (IHC - Paraffin), ELISA (EIA)
Application Notes for anti-DREG antibody
ELISA, IHC-P (10 ug/ml)
Usage: Immunohistochemistry with formalin-fixed paraffin-embedded tissues requires pretreatment with Proteinase K.

Immunohistochemistry (IHC) of anti-DREG antibody

Anti-GPR126 antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Rabbit Anti-DREG Polyclonal Antibody – Cat# MBS242393

Immunohistochemistry (IHC) of anti-DREG antibody

Anti-GPR126 antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Rabbit Anti-DREG Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS242393

Other Notes

Small volumes of anti-DREG antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for DREG purchase

MBS242393 is an antibody targeting DREG. Also known as Rabbit Polyclonal to Human DREG / GPR126. Reactive in Gibbon, Gorilla, Human, Mouse
Predicted Reactivity: Monkey, Rat, Bat, Bovine, Dog, Horse, Pig, Rabbit (at least 90% immunogen sequence identity). Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for DREG. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
G-protein coupled receptor 126 isoform alpha 1
NCBI Official Synonym Full Names
G protein-coupled receptor 126
NCBI Official Symbol
GPR126
NCBI Official Synonym Symbols
APG1; DREG; VIGR; PS1TP2
UniProt Protein Name
G-protein coupled receptor 126
UniProt Synonym Protein Names
Developmentally regulated G-protein-coupled receptor; Vascular inducible G protein-coupled receptor
UniProt Gene Name
GPR126
UniProt Synonym Gene Names
DREG; VIGR
UniProt Entry Name
GP126_HUMAN
NCBI Protein Information
G-protein coupled receptor 126; HBV PreS1-transactivated protein 2; vascular inducible G protein-coupled receptor; vascular-inducible G protein-coupled receptor; developmentally regulated G-protein-coupled receptor

NCBI Summary for DREG

This gene, which is upregulated in human umbilical vein endothelial cells, encodes a G protein-coupled receptor. Variations in this gene can affect a person's stature. Multiple transcript variants encoding different proteins have been found for this gene. [provided by RefSeq, Mar 2009]

UniProt Comments for DREG

GPR126: Orphan receptor. May be required for normal differentiation of promyelinating Schwann cells and for normal myelination of axons. Signals probably through G-proteins to transiently elevate cAMP levels. Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: Receptor, GPCR; Membrane protein, multi-pass; GPCR, family 2; Membrane protein, integral

Chromosomal Location of Human Ortholog: 6q24.1

Cellular Component: integral to membrane; plasma membrane

Molecular Function: G-protein coupled receptor activity

Biological Process: G-protein coupled receptor protein signaling pathway
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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