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GUCY1B3 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS242403

MBS242403 is an antibody targeting GUCY1B3. Also known as Rabbit Polyclonal to Human GUCY1B3. Reactive in Human, Mouse, Rat. Host: Rabbit. More details

$700 / 0.25 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
GUCY1B3, Polyclonal Antibody
Full Product Name
Rabbit Polyclonal to Human GUCY1B3
Product Gene Name
Product Synonym Names
Anti-GUCY1B3 Antibody (aa189-207) IHC-plus; GUCY1B3; GC-S-beta-1; GC-SB3; GCS-beta-1; GUC1B3; GUCB3; GUCSB3; GUCY1B1; GCS-beta-3; Human GUCY1B3
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
10 mM PBS, pH 7.4, 1% BSA, 0.09% sodium azide
Purity/Purification
Immunoaffinity Purified
Concentration
0.2 mg/ml (lot specific)
Preparation and Storage
Store at 2 degree C to 8 degree C degrees. Do not freeze.
Molecular Weight
68,165 Da
OMIM
139397
3D Structure
ModBase 3D Structure for Q02153
Target Species
Human
Immunogen Description
A synthetic peptide from aa 189-207 of human guanylyl cyclase beta 1, soluble.
Immunogen Type
Synthetic peptide
Immunogen
GUCY1B3 antibody was raised against a synthetic peptide from aa 189-207 of human guanylyl cyclase beta 1, soluble.
Antigen Modification
aa189-207

Product Categories/Family for anti-GUCY1B3 antibody

Applications Tested/Suitable for anti-GUCY1B3 antibody
Immunohistochemistry (IHC - Paraffin)
Application Notes for anti-GUCY1B3 antibody
IHC-P (10 ug/ml)
Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary anti...

Immunohistochemistry (IHC) of anti-GUCY1B3 antibody

Anti-GUCY1B3 / Guanylyl Cyclase Beta 1 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
Rabbit Anti-GUCY1B3 Polyclonal Antibody – Cat# MBS242403

Immunohistochemistry (IHC) of anti-GUCY1B3 antibody

Anti-GUCY1B3 / Guanylyl Cyclase Beta 1 antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
Rabbit Anti-GUCY1B3 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS242403

Other Notes

Small volumes of anti-GUCY1B3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for GUCY1B3. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
guanylate cyclase soluble subunit beta-1 isoform 2
NCBI Official Synonym Full Names
guanylate cyclase 1, soluble, beta 3
NCBI Official Symbol
GUCY1B3
NCBI Official Synonym Symbols
GUCB3; GC-SB3; GUC1B3; GUCSB3; GUCY1B1; GC-S-beta-1
UniProt Protein Name
Guanylate cyclase soluble subunit beta-1
UniProt Synonym Protein Names
Guanylate cyclase soluble subunit beta-3; GCS-beta-3; Soluble guanylate cyclase small subunit
UniProt Gene Name
GUCY1B3
UniProt Synonym Gene Names
GUC1B3; GUCSB3; GUCY1B1; GCS-beta-1; GCS-beta-3
UniProt Entry Name
GCYB1_HUMAN
NCBI Protein Information
guanylate cyclase soluble subunit beta-1; GCS-beta-1; GCS-beta-3; soluble guanylate cyclase small subunit; guanylate cyclase soluble subunit beta-3

NCBI Summary for GUCY1B3

This gene encodes the beta subunit of the soluble guanylate cyclase (sGC), which catalyzes the conversion of GTP (guanosine triphosphate) to cGMP (cyclic guanosine monophosphate). The encoded protein contains an HNOX domain, which serves as a receptor for ligands such as nitric oxide, oxygen and nitrovasodilator drugs. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014]
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UniProt Comments for GUCY1B3

GUCY1B3: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. Heterodimer of an alpha and a beta chain. 2 isoforms of the human protein are produced by alternative splicing

Protein type: EC 4.6.1.2; Receptor, misc.; Guanylyl cyclase; Lyase; Nucleotide Metabolism - purine

Chromosomal Location of Human Ortholog: 4q31.3-q33

Cellular Component: guanylate cyclase complex, soluble; intracellular membrane-bound organelle; cytoplasm

Molecular Function: guanylate cyclase activity; GTP binding; protein heterodimerization activity; metal ion binding; heme binding; receptor activity; Hsp90 protein binding

Biological Process: cGMP biosynthetic process; blood circulation; blood coagulation; nitric oxide mediated signal transduction
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-GUCY1B3 antibody

 Reference Product  PubMed Publications
 GUCY1A3 antibody  >5 publications with GUCY1B3 and GUCY1A3
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