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CD1A Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS242463

MBS242463 is an antibody targeting CD1A. Also known as Rabbit Polyclonal [clone L21-A] to Human CD1A. Reactive in Human. Host: Rabbit. More details

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Sample Manual Insert View PDF
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Testing Data View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Product Name
CD1A, Polyclonal Antibody
Full Product Name
Rabbit Polyclonal [clone L21-A] to Human CD1A
Product Gene Name
Product Synonym Names
Anti-CD1A Antibody (clone L21-A) IHC-plus; CD1A; CD1; CD1A antigen; a polypeptide; CD1a molecule; FCB6; HTA1; HTa1 thymocyte antigen; R4; T6; CD1a antigen; Cluster of differentiation 1 A; Human CD1A
Clonality
Polyclonal
Clone Number
L21-A
Host
Rabbit
Species Reactivity
Human
Form/Format
20 mM Tris-HCl, pH 8.0, 20 mg/ml BSA, 0.05% sodium azide
Purity/Purification
Purified
Preparation and Storage
Store at -20 degree C.
Molecular Weight
37,077 Da
OMIM
188370
3D Structure
ModBase 3D Structure for P06126
Target Species
Human
Immunogen Description
Peptide derived from C-terminal region, near the transmembrane domain of human CD1-a
Applications Tested/Suitable for anti-CD1A antibody
Immunohistochemistry (IHC - Paraffin)
Application Notes for anti-CD1A antibody
IHC-P (1:100 - 1:200)
Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary anti...

Immunohistochemistry (IHC) of anti-CD1A antibody

Anti-CD1A antibody IHC of human thymus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.
Rabbit Anti-CD1A Polyclonal Antibody – Cat# MBS242463

Other Notes

Small volumes of anti-CD1A antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for CD1A. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
T-cell surface glycoprotein CD1a
NCBI Official Synonym Full Names
CD1a molecule
NCBI Official Symbol
CD1A
NCBI Official Synonym Symbols
R4; T6; CD1; FCB6; HTA1
UniProt Protein Name
T-cell surface glycoprotein CD1a
UniProt Synonym Protein Names
T-cell surface antigen T6/Leu-6; hTa1 thymocyte antigen; CD_antigen: CD1a
UniProt Gene Name
CD1A
UniProt Synonym Gene Names
hTa1 thymocyte antigen
UniProt Entry Name
CD1A_HUMAN
NCBI Protein Information
T-cell surface glycoprotein CD1a; hTa1 thymocyte antigen; CD1A antigen, a polypeptide; cluster of differentiation 1 A; T-cell surface antigen T6/Leu-6; cortical thymocyte antigen CD1A; differentiation antigen CD1-alpha-3; epidermal dendritic cell marker CD1a

NCBI Summary for CD1A

This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes to the plasma membrane and to recycling vesicles of the early endocytic system. Alternatively spliced transcript variants have been observed, but their biological validity has not been determined. [provided by RefSeq, Jul 2008]
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UniProt Comments for CD1A

CD1A: Antigen-presenting protein that binds self and non-self lipid and glycolipid antigens and presents them to T-cell receptors on natural killer T-cells.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 1q23.1

Cellular Component: integral to plasma membrane; plasma membrane; endosome membrane

Molecular Function: protein binding; beta-2-microglobulin binding; exogenous lipid antigen binding; endogenous lipid antigen binding

Biological Process: antigen processing and presentation, exogenous lipid antigen via MHC class Ib; immune response
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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