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ELOVL6 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS242486

MBS242486 is an antibody targeting ELOVL6. Also known as Rabbit Polyclonal to Human ELOVL6. Reactive in Human, Mouse, Rat. Host: Rabbit. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
ELOVL6, Polyclonal Antibody
Full Product Name
Rabbit Polyclonal to Human ELOVL6
Product Gene Name
Product Synonym Names
Anti-ELOVL6 Antibody (N-Terminus) IHC-plus; ELOVL6; FAE; ELOVL fatty acid elongase 6; HELO2; Fatty acid elongase 2; Fatty acyl-CoA elongase; LCE; ELOVL FA elongase 6; FACE; Long-chain fatty-acyl elongase; Human ELOVL6
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
PBS, 0.02% sodium azide.
Purity/Purification
Immunoaffinity Purified
Concentration
1 mg/ml (lot specific)
Preparation and Storage
Short term 4 degree C, long term aliquot and store at -20 degree C, avoid freeze thaw cycles. Store undiluted.
Molecular Weight
31,376 Da
OMIM
611546
3D Structure
ModBase 3D Structure for Q9H5J4
Target Species
Human
Immunogen Description
16 amino acid peptide near the amino terminus of the human ELOVL6.
Immunogen
ELOVL6 antibody was raised against 16 amino acid peptide near the amino terminus of the human ELOVL6.
Antigen Modification
N-Terminus
Applications Tested/Suitable for anti-ELOVL6 antibody
Immunohistochemistry (IHC - Paraffin), Western Blot (WB), ELISA (EIA)
Application Notes for anti-ELOVL6 antibody
ELISA, IHC-P (5 ug/ml), WB (1 - 2 ug/ml)
Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary anti...

Immunohistochemistry (IHC) of anti-ELOVL6 antibody

Anti-ELOVL6 antibody IHC of human lung. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Rabbit Anti-ELOVL6 Polyclonal Antibody – Cat# MBS242486

Immunofluorescence (IF) of anti-ELOVL6 antibody

Immunofluorescence of ELOVL6 in Human Brain cells with ELOVL6 antibody at 20 ug/ml.
Rabbit Anti-ELOVL6 Polyclonal Antibody, Immunofluorescence (IF) – Cat# MBS242486

Western Blot (WB) of anti-ELOVL6 antibody

Western blot of ELOVL6 in Human brain tissue lysate with ELOVL6 antibody at (A) 1 and (B) 2 ug/ml.
Rabbit Anti-ELOVL6 Polyclonal Antibody, Western Blot (WB) – Cat# MBS242486

Other Notes

Small volumes of anti-ELOVL6 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for ELOVL6. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
elongation of very long chain fatty acids protein 6
NCBI Official Synonym Full Names
ELOVL fatty acid elongase 6
NCBI Official Symbol
ELOVL6
NCBI Official Synonym Symbols
FAE; LCE; FACE
UniProt Protein Name
Elongation of very long chain fatty acids protein 6
UniProt Synonym Protein Names
3-keto acyl-CoA synthase ELOVL6; ELOVL fatty acid elongase 6; ELOVL FA elongase 6; Fatty acid elongase 2; hELO2; Fatty acyl-CoA elongase; Long-chain fatty-acyl elongase; Very-long-chain 3-oxoacyl-CoA synthase 6
UniProt Gene Name
ELOVL6
UniProt Synonym Gene Names
FACE; LCE; ELOVL FA elongase 6; hELO2
UniProt Entry Name
ELOV6_HUMAN
NCBI Protein Information
elongation of very long chain fatty acids protein 6; hELO2; ELOVL FA elongase 6; fatty acid elongase 2; fatty acyl-CoA elongase; long-chain fatty-acyl elongase; 3-keto acyl-CoA synthase ELOVL6; very-long-chain 3-oxoacyl-CoA synthase 6; ELOVL family member 6, elongation of long chain fatty acids (FEN1/Elo2, SUR4/Elo3-like, yeast)

NCBI Summary for ELOVL6

Fatty acid elongases (EC 6.2.1.3), such as ELOVL6, use malonyl-CoA as a 2-carbon donor in the first and rate-limiting step of fatty acid elongation (Moon et al., 2001 [PubMed 11567032]).[supplied by OMIM, Mar 2008]

UniProt Comments for ELOVL6

ELOVL6: Condensing enzyme that catalyzes the synthesis of saturated and monounsaturated fatty acids. Highest activity toward C16:0 acyl-CoAs. Belongs to the ELO family.

Protein type: Membrane protein, multi-pass; Membrane protein, integral; EC 2.3.1.199

Chromosomal Location of Human Ortholog: 4q25

Cellular Component: endoplasmic reticulum membrane; endoplasmic reticulum; integral to endoplasmic reticulum membrane

Molecular Function: protein binding; transferase activity, transferring groups other than amino-acyl groups

Biological Process: long-chain fatty acid biosynthetic process; triacylglycerol biosynthetic process; fatty acid elongation, saturated fatty acid; cellular lipid metabolic process
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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