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GLP2R Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS242499

GLP2R, a Glucagon Receptor, is closely related to the Glucagon Receptor and to the GLP1 Receptor. The glucagon-like peptides (GLP-1 and GLP-2) are proglucagon-derived peptides cosecreted from gut endocrine cells in response to nutrient ingestion. The actions… More details

$630 / 0.05 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
GLP2R / Glp-2, Polyclonal Antibody
Full Product Name
Rabbit Polyclonal to Human GLP2R / Glp-2
Product Gene Name
Product Synonym Gene Name
Glp-2
Product Synonym Names
Anti-GLP2R / Glp-2 Antibody (Internal) IHC-plus; GLP2R; Glp-2; GLP-2-R; GLP-2 receptor; GLP-2R; Glp2 receptor; Human GLP2R; Glp-2
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human, Monkey
Predicted Reactivity: Gorilla, Gibbon (at least 90% immunogen sequence identity)
Form/Format
PBS, 0.1% sodium azide.
Purity/Purification
Immunoaffinity Purified
Concentration
1 mg/ml (lot specific)
Specificity
Human GLP2R. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Preparation and Storage
Long term: -70 degree C; Short term: +4 degree C
Molecular Weight
63,001 Da
OMIM
603659
3D Structure
ModBase 3D Structure for O95838
Target Species
Human
Immunogen Description
Synthetic 16 amino acid peptide from internal region of human GLP2R. Percent identity with other species by BLAST analysis: Human, Monkey, Marmoset (100%); Gorilla, Gibbon (94%); Rat, Dog, Bovine, Elephant, Panda (81%).
Immunogen Type
Synthetic peptide
Immunogen
GLP2R / Glp-2 antibody was raised against synthetic 16 amino acid peptide from internal region of human GLP2R. Percent identity with other species by BLAST analysis: Human, Monkey, Marmoset (100%); Gorilla, Gibbon (94%); Rat, Dog, Bovine, Elephant, Panda (81%).
Antigen Modification
Internal
Applications Tested/Suitable for anti-GLP2R antibody
Immunohistochemistry (IHC - Paraffin)
Application Notes for anti-GLP2R antibody
IHC-P (5 - 10 ug/ml)
Usage: Immunohistochemistry with formalin-fixed paraffin-embedded tissues requires pretreatment with Proteinase K.

Immunohistochemistry (IHC) of anti-GLP2R antibody

Anti-GLP2R antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Rabbit Anti-GLP2R Polyclonal Antibody – Cat# MBS242499

Immunohistochemistry (IHC) of anti-GLP2R antibody

Anti-GLP2R antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Rabbit Anti-GLP2R Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS242499

Other Notes

Small volumes of anti-GLP2R antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for GLP2R purchase

MBS242499 is an antibody targeting GLP2R. Also known as Rabbit Polyclonal to Human GLP2R / Glp-2. Reactive in Human, Monkey
Predicted Reactivity: Gorilla, Gibbon (at least 90% immunogen sequence identity). Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for GLP2R. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
glucagon-like peptide 2 receptor
NCBI Official Synonym Full Names
glucagon-like peptide 2 receptor
NCBI Official Symbol
GLP2R
UniProt Protein Name
Glucagon-like peptide 2 receptor
UniProt Gene Name
GLP2R
UniProt Synonym Gene Names
GLP-2 receptor; GLP-2-R; GLP-2R
UniProt Entry Name
GLP2R_HUMAN
NCBI Protein Information
glucagon-like peptide 2 receptor; GLP-2 receptor

NCBI Summary for GLP2R

This gene encodes a G protein-coupled receptor that is closely related to the glucagon receptor and binds to glucagon-like peptide-2 (GLP2). Signalling through GLP2 stimulates intestinal growth and increases villus height in the small intestine, concomitant with increased crypt cell proliferation and decreased enterocyte apoptosis. [provided by RefSeq, Dec 2014]
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UniProt Comments for GLP2R

GLP2R: This is a receptor for glucagon-like peptide 2. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 2 family.

Protein type: GPCR, family 2; Receptor, GPCR; Membrane protein, multi-pass; Membrane protein, integral

Chromosomal Location of Human Ortholog: 17p13.3

Cellular Component: plasma membrane; integral to membrane

Molecular Function: G-protein coupled receptor activity; glucagon receptor activity

Biological Process: G-protein signaling, coupled to cAMP nucleotide second messenger; positive regulation of cell proliferation
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-GLP2R antibody

Organs/Tissues associated with anti-GLP2R antibody

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