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SLITRK6 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS242572

SLITEK6 is a member of the SLITRK (SLIT-and NTRK-like Famliy) family of proteins. These proteins are primarily expressed in brain and control neurite outgrowth. SLITEK6 is an integral membrane protein with 2 N-terminal leucine-rich repeats (LRR) domains and a… More details

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Product Overview

Product Name
SLITRK6, Polyclonal Antibody
Full Product Name
Rabbit Polyclonal to Human SLITRK6
Product Gene Name
Product Synonym Names
Anti-SLITRK6 Antibody (Internal) IHC-plus; SLITRK6; Slit and trk like gene 6; SLIT and NTRK-like protein 6; Human SLITRK6
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
PBS, 0.02% sodium azide.
Purity/Purification
Immunoaffinity Purified
Concentration
1 mg/ml (lot specific)
Preparation and Storage
Short term 4 degree C, long term aliquot and store at -20 degree C, avoid freeze thaw cycles. Store undiluted.
Molecular Weight
95,110 Da
OMIM
phenotype 609681
3D Structure
ModBase 3D Structure for Q9H5Y7
Target Species
Human
Immunogen Description
13amino acid peptide from near the center of human Slitrk6.
Immunogen
SLITRK6 antibody was raised against 13amino acid peptide from near the center of human Slitrk6.
Antigen Modification
Internal
Applications Tested/Suitable for anti-SLITRK6 antibody
Immunohistochemistry (IHC - Paraffin), Western Blot (WB), ELISA (EIA)
Application Notes for anti-SLITRK6 antibody
ELISA, IHC-P (10 ug/ml), WB (0.5 - 1 ug/ml)
Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary anti...

Immunohistochemistry (IHC) of anti-SLITRK6 antibody

Anti-SLITRK6 antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
Rabbit Anti-SLITRK6 Polyclonal Antibody – Cat# MBS242572

Immunohistochemistry (IHC) of anti-SLITRK6 antibody

Anti-SLITRK6 antibody IHC of human adrenal. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
Rabbit Anti-SLITRK6 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS242572

Immunofluorescence (IF) of anti-SLITRK6 antibody

Immunofluorescence of Slitrk6 in Human Brain cells with Slitrk6 antibody at 20 ug/ml.
Rabbit Anti-SLITRK6 Polyclonal Antibody, Immunofluorescence (IF) – Cat# MBS242572

Western Blot (WB) of anti-SLITRK6 antibody

Western blot of Slitrk6 in mouse lung tissue lysate with Slitrk6 antibody at (A) 0.5 and (B) 1 ug/ml.
Rabbit Anti-SLITRK6 Polyclonal Antibody, Western Blot (WB) – Cat# MBS242572

Other Notes

Small volumes of anti-SLITRK6 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SLITRK6 purchase

MBS242572 is an antibody targeting SLITRK6. Also known as Rabbit Polyclonal to Human SLITRK6. Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for SLITRK6. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
SLIT and NTRK-like protein 6
NCBI Official Synonym Full Names
SLIT and NTRK-like family, member 6
NCBI Official Symbol
SLITRK6
NCBI Official Synonym Symbols
DFNMYP
UniProt Protein Name
SLIT and NTRK-like protein 6
UniProt Gene Name
SLITRK6
UniProt Entry Name
SLIK6_HUMAN
NCBI Protein Information
SLIT and NTRK-like protein 6; 4832410J21Rik; slit and trk like gene 6

NCBI Summary for SLITRK6

This gene encodes a member of the SLITRK protein family. Members of this family are integral membrane proteins that are characterized by two N-terminal leucine-rich repeat (LRR) domains and a C-terminal region that shares homology with trk neurotrophin receptors. This protein functions as a regulator of neurite outgrowth required for normal hearing and vision. Mutations in this gene are a cause of myopia and deafness. [provided by RefSeq, Dec 2014]
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UniProt Comments for SLITRK6

SLITRK6: Suppresses neurite outgrowth. Belongs to the SLITRK family.

Protein type: Cell surface; Membrane protein, integral

Chromosomal Location of Human Ortholog: 13q31.1

Cellular Component: cell surface; integral to plasma membrane

Biological Process: lens development in camera-type eye; vestibulocochlear nerve development; startle response; sensory perception of sound; synaptogenesis; visual perception; axonogenesis; adult locomotory behavior; multicellular organism growth; auditory receptor cell morphogenesis; auditory behavior; linear vestibuloocular reflex

Disease: Deafness And Myopia
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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