Goat Anti-APOH Polyclonal Antibody – Cat# MBS242583

Anti-APOH / Apolipoprotein H antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.

APOH Antibody – Goat Polyclonal

Name: APOH Antibody; Polyclonal; Goat; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS242583
Price: 790 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS242583

Apolipoprotein H has been implicated in a variety of physiologic pathways including lipoprotein metabolism, coagulation, and the production of antiphospholipid autoantibodies. APOH may be a required cofactor for anionic phospholipid binding by the… More details

$790 / 0.05 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

APOH / Apolipoprotein H, Polyclonal Antibody

Full Product Name

Goat Polyclonal (IgG) to Human APOH / Apolipoprotein H

Product Gene Name

anti-APOH antibody

Product Synonym Names

Anti-APOH / Apolipoprotein H Antibody IHC-plus; APOH; Apo-H; Anticardiolipin cofactor; Apolipoprotein H; B2GP1; B2GPI; Beta-2-glycoprotein I; APC inhibitor; Beta(2)GPI; BG; B2G1; Beta-2-glycoprotein 1; Human APOH; Apolipoprotein H

Clonality

Polyclonal

Isotype

IgG

Host

Goat

Species Reactivity

Human

Form/Format

10 mM HEPES, pH 7.4, 0.15 M sodium chloride, 50% glycerol.

Purity/Purification

Immunoaffinity Purified

Concentration

2 mg/ml (lot specific)

Specificity

Recognizes human beta2GP-I. A single precipitin arc is observed with normal plasma. No arc was seen with beta2GP-I deficient plasma.

Preparation and Storage

Long term: -20 degree C; Short term: +4 degree C. Avoid repeat freeze-thaw cycles.

Molecular Weight

38,298 Da

OMIM

138700

3D Structure

ModBase 3D Structure for P02749

Target Species

Human

Immunogen Description

Human beta2-Glycoprotein-I (beta2GP-I) purified from plasma.

Immunogen Type

Purified protein

Immunogen

APOH / Apolipoprotein H antibody was raised against human beta2-Glycoprotein-I (beta2GP-I) purified from plasma.

Applications Tested/Suitable for anti-APOH antibody

Immunohistochemistry (IHC - Paraffin), ELISA (EIA), Immunoelectrophoresis

Application Notes for anti-APOH antibody

ELISA, IE, IHC-P (2.5 ug/ml)
Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary anti...

Other Notes

Small volumes of anti-APOH antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for APOH purchase

MBS242583 is an antibody targeting APOH. Also known as Goat Polyclonal (IgG) to Human APOH / Apolipoprotein H. Reactive in Human. Host: Goat.

Additional Details

NCBI/Uniprot data below describe general gene information for APOH. It may not necessarily be applicable to this product.

NCBI GI #

153266841

NCBI GeneID

350

NCBI Accession #

NP_000033.2

UniProt Primary Accession #

P02749

UniProt Secondary Accession #

Q9UCN7; B2R9M3

UniProt Related Accession #

P02749

GenBank Nucleotide #

NM_000042.2

NCBI Official Full Name

beta-2-glycoprotein 1

NCBI Official Synonym Full Names

apolipoprotein H (beta-2-glycoprotein I)

NCBI Official Symbol

APOH

NCBI Official Synonym Symbols

BG; B2G1; B2GP1

UniProt Protein Name

Beta-2-glycoprotein 1

UniProt Synonym Protein Names

APC inhibitor; Activated protein C-binding protein; Anticardiolipin cofactor; Apolipoprotein H; Apo-H; Beta-2-glycoprotein I; B2GPI; Beta(2)GPI

Protein Family

Beta-2-glycoprotein

UniProt Gene Name

APOH

UniProt Synonym Gene Names

B2G1; Apo-H; B2GPI; Beta(2)GPI

UniProt Entry Name

APOH_HUMAN

NCBI Protein Information

beta-2-glycoprotein 1; B2GPI; apo-H; beta(2)GPI; APC inhibitor; anticardiolipin cofactor; activated protein C-binding protein

UniProt Comments for APOH

APOH: Binds to various kinds of negatively charged substances such as heparin, phospholipids, and dextran sulfate. May prevent activation of the intrinsic blood coagulation cascade by binding to phospholipids on the surface of damaged cells.

Protein type: Secreted, signal peptide; Lipid-binding; Secreted

Chromosomal Location of Human Ortholog: 17q24.2

Cellular Component: extracellular matrix; extracellular space; chylomicron; cell surface

Molecular Function: heparin binding; identical protein binding; protein binding; phospholipid binding; glycoprotein binding; lipid binding

Biological Process: negative regulation of myeloid cell apoptosis; negative regulation of angiogenesis; negative regulation of fibrinolysis; positive regulation of blood coagulation; triacylglycerol metabolic process; negative regulation of endothelial cell proliferation; negative regulation of blood coagulation; positive regulation of lipoprotein lipase activity; triacylglycerol transport; blood coagulation, intrinsic pathway; plasminogen activation; regulation of fibrinolysis

Research Articles on APOH

1. Serum beta2-GPI-Lp(a) levels were increased in ischemic stroke patients

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-APOH antibody

Reference Product	PubMed Publications
APOC3 antibody	>4 publications with APOH and APOC3
APOA2 antibody	>3 publications with APOH and APOA2
AMBP antibody	>1 publications with APOH and AMBP
SERPINC1 antibody	>1 publications with APOH and SERPINC1
AHSG antibody	>1 publications with APOH and AHSG
LDLR antibody	>1 publications with APOH and LDLR

Diseases associated with anti-APOH antibody

Disease Name	Pubmed Publications
Autoimmune Diseases Antibodies	>11 publications with APOH and Autoimmune Diseases
Brain Diseases Antibodies	>8 publications with APOH and Brain Diseases
Liver Diseases Antibodies	>8 publications with APOH and Liver Diseases
Inflammation Antibodies	>7 publications with APOH and Inflammation
Heart Diseases Antibodies	>6 publications with APOH and Heart Diseases
Hemorrhage Antibodies	>5 publications with APOH and Hemorrhage
Liver Neoplasms Antibodies	>3 publications with APOH and Liver Neoplasms
Atherosclerosis Antibodies	>3 publications with APOH and Atherosclerosis
Hypertension Antibodies	>3 publications with APOH and Hypertension
Kidney Diseases Antibodies	>2 publications with APOH and Kidney Diseases

Organs/Tissues associated with anti-APOH antibody

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>49 publications with APOH and Blood
Liver Antibodies	>25 publications with APOH and Liver
Brain Antibodies	>5 publications with APOH and Brain
Muscle Antibodies	>4 publications with APOH and Muscle
Heart Antibodies	>4 publications with APOH and Heart
Lung Antibodies	>3 publications with APOH and Lung
Kidney Antibodies	>3 publications with APOH and Kidney
Intestine Antibodies	>2 publications with APOH and Intestine
Embryonic Tissue Antibodies	>1 publications with APOH and Embryonic Tissue
Spleen Antibodies	>1 publications with APOH and Spleen