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BAI3 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS242592

BAI3 is an Orphan-B GPCR with an unknown ligand. Two isoforms of BAI3 are produced by alternative splicing. Along with BAI3, there are two other brain-specific angiogenesis inhibitor genes, designated BAI1 and BAI2, which have similar tissue specificities and… More details

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Product Overview

Product Name
BAI3, Polyclonal Antibody
Full Product Name
Rabbit Polyclonal to Human BAI3
Product Gene Name
Product Synonym Names
Anti-BAI3 Antibody (aa1506-1522) IHC-plus; BAI3; KIAA0550; Human BAI3
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Bat, Gibbon, Chicken, Dog, Xenopus, Gorilla, Human, Monkey, Mouse, Rabbit, Rat
Predicted Reactivity: Bovine, Horse, Zebrafish (at least 90% immunogen sequence identity)
Form/Format
PBS, 0.09% sodium azide.
Purity/Purification
Protein G Purified
Concentration
1 mg/ml (lot specific)
Specificity
KLH conjugated synthetic peptide comprising amino acids 1506 - 1522 [CLNLPLDVQEGDFQTEV] of the human brain-specific angiogenesis inhibitor 3 (BAI3) protein.
Preparation and Storage
Long term: -20 degree C; Short term: +4 degree C. Avoid repeat freeze-thaw cycles.
Molecular Weight
55,035 Da
OMIM
602684
3D Structure
ModBase 3D Structure for O60242
Target Species
Human
Immunogen Description
Synthetic peptide from human BAI3. Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Marmoset, Mouse, Rat, Elephant, Panda, Dog, Bat, Rabbit, Opossum, Chicken, Lizard, Xenopus (100%); Bovine, Horse, Pufferfish, Zebrafish (94%).
Immunogen Type
Synthetic peptide
Immunogen
BAI3 antibody was raised against synthetic peptide from human BAI3. Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Marmoset, Mouse, Rat, Elephant, Panda, Dog, Bat, Rabbit, Opossum, Chicken, Lizard, Xenopus (100%); Bovine, Horse, Pufferfish, Zebrafish (94%); Stickleback (88%).
Antigen Modification
aa1506-1522
Applications Tested/Suitable for anti-BAI3 antibody
Immunohistochemistry (IHC - Paraffin), ELISA (EIA)
Application Notes for anti-BAI3 antibody
ELISA (1:000 - 1:1000), IHC-P (15 ug/ml)
Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary anti...

Immunohistochemistry (IHC) of anti-BAI3 antibody

Anti-BAI3 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 15 ug/ml.
Rabbit Anti-BAI3 Polyclonal Antibody – Cat# MBS242592

Immunohistochemistry (IHC) of anti-BAI3 antibody

Anti-BAI3 antibody IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 15 ug/ml.
Rabbit Anti-BAI3 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS242592

Other Notes

Small volumes of anti-BAI3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for BAI3 purchase

MBS242592 is an antibody targeting BAI3. Also known as Rabbit Polyclonal to Human BAI3. Reactive in Bat, Gibbon, Chicken, Dog, Xenopus, Gorilla, Human, Monkey, Mouse, Rabbit, Rat
Predicted Reactivity: Bovine, Horse, Zebrafish (at least 90% immunogen sequence identity). Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for BAI3. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
brain-specific angiogenesis inhibitor 3
NCBI Official Synonym Full Names
brain-specific angiogenesis inhibitor 3
NCBI Official Symbol
BAI3
UniProt Protein Name
Brain-specific angiogenesis inhibitor 3
UniProt Gene Name
BAI3
UniProt Synonym Gene Names
KIAA0550
UniProt Entry Name
BAI3_HUMAN
NCBI Protein Information
brain-specific angiogenesis inhibitor 3; dJ91B17.1 (brain-specific angiogenesis inhibitor 3)

NCBI Summary for BAI3

This p53-target gene encodes a brain-specific angiogenesis inhibitor, a seven-span transmembrane protein, and is thought to be a member of the secretin receptor family. Brain-specific angiogenesis proteins BAI2 and BAI3 are similar to BAI1 in structure, have similar tissue specificities, and may also play a role in angiogenesis. [provided by RefSeq, Jul 2008]
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UniProt Comments for BAI3

BAI3: May regulate the number of excitatory synapses that are formed on hippocampus neurons. Has no effect on inhibitory synapses. Might be involved in angiogenesis inhibition and suppression of glioblastoma. Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily.

Protein type: Membrane protein, integral; GPCR, family 2; Membrane protein, multi-pass; Receptor, GPCR

Chromosomal Location of Human Ortholog: 6q12

Cellular Component: integral to membrane; plasma membrane

Molecular Function: G-protein coupled receptor activity

Biological Process: G-protein coupled receptor protein signaling pathway; negative regulation of angiogenesis
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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