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GDI2 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS242757

MBS242757 is an antibody targeting GDI2. Also known as Rabbit Polyclonal to Human GDI2. Reactive in Human. Host: Rabbit. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
GDI2, Polyclonal Antibody
Full Product Name
Rabbit Polyclonal to Human GDI2
Product Gene Name
Product Synonym Names
Anti-GDI2 Antibody IHC-plus; GDI2; GDP dissociation inhibitor 2; GDI-2; Rab GDI beta; RABGDIB; Human GDI2
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human
Form/Format
0.1 M Tris-glycine, pH 7, 10% Glycerol, 0.01% Thimerosal
Purity/Purification
Immunoaffinity Purified
Concentration
1 mg/ml (lot specific)
Specificity
Human Rho GDI2. Predicted cross-reactivity based on amino acid sequence homology: mouse (90%), rat (89%), bovine (93%).
Preparation and Storage
Aliquot and store at -20 degree C. Minimize freezing and thawing.
Molecular Weight
45,619 Da
OMIM
600767
3D Structure
ModBase 3D Structure for P50395
Target Species
Human
Immunogen Description
Recombinant protein fragment containing a sequence corresponding to a region within amino acids 1 and 197 of Human Rho GDI2.
Immunogen Type
Recombinant protein
Immunogen
GDI2 antibody was raised against recombinant protein fragment containing a sequence corresponding to a region within amino acids 1 and 197 of Human Rho GDI2.
Applications Tested/Suitable for anti-GDI2 antibody
Immunohistochemistry (IHC - Paraffin), Western Blot (WB)
Application Notes for anti-GDI2 antibody
IHC-P (10 ug/ml), WB (1:500 - 1:3000)

Immunohistochemistry (IHC) of anti-GDI2 antibody

Anti-GDI2 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
Rabbit Anti-GDI2 Polyclonal Antibody – Cat# MBS242757

Immunohistochemistry (IHC) of anti-GDI2 antibody

Anti-GDI2 antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
Rabbit Anti-GDI2 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS242757

Western Blot (WB) of anti-GDI2 antibody

Sample(30g whole cell lysate). A: 293T. B: A431. C: H1299. D: HeLa S3. E: Hep G2. 12% SDS PAGE. GDI2 antibody diluted at 1:1000
Rabbit Anti-GDI2 Polyclonal Antibody, Western Blot (WB) – Cat# MBS242757

Other Notes

Small volumes of anti-GDI2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for GDI2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
rab GDP dissociation inhibitor beta isoform 1
NCBI Official Synonym Full Names
GDP dissociation inhibitor 2
NCBI Official Symbol
GDI2
NCBI Official Synonym Symbols
RABGDIB; HEL-S-46e
UniProt Protein Name
Rab GDP dissociation inhibitor beta
UniProt Synonym Protein Names
Guanosine diphosphate dissociation inhibitor 2; GDI-2
UniProt Gene Name
GDI2
UniProt Synonym Gene Names
RABGDIB; Rab GDI beta; GDI-2
UniProt Entry Name
GDIB_HUMAN
NCBI Protein Information
rab GDP dissociation inhibitor beta; GDI-2; rab GDI beta; rab GDP-dissociation inhibitor, beta; guanosine diphosphate dissociation inhibitor 2; epididymis secretory sperm binding protein Li 46e

NCBI Summary for GDI2

GDP dissociation inhibitors are proteins that regulate the GDP-GTP exchange reaction of members of the rab family, small GTP-binding proteins of the ras superfamily, that are involved in vesicular trafficking of molecules between cellular organelles. GDIs slow the rate of dissociation of GDP from rab proteins and release GDP from membrane-bound rabs. GDI2 is ubiquitously expressed. The GDI2 gene contains many repetitive elements indicating that it may be prone to inversion/deletion rearrangements. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008]
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UniProt Comments for GDI2

GDI2: Regulates the GDP/GTP exchange reaction of most Rab proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them. Belongs to the Rab GDI family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: G protein regulator, misc.; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 10p15

Cellular Component: Golgi apparatus; focal adhesion; membrane; cytoplasm; cytosol; vesicle

Molecular Function: small GTPase binding; protein binding; Rab GDP-dissociation inhibitor activity

Biological Process: vesicle-mediated transport; protein transport; regulation of small GTPase mediated signal transduction; small GTPase mediated signal transduction; signal transduction
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-GDI2 antibody

 Reference Product  PubMed Publications
 ARHGDIB antibody  >1 publications with GDI2 and ARHGDIB
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