Rabbit Anti-NMUR2 Polyclonal Antibody – Cat# MBS242934

Anti-NMUR2 antibody IHC of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

NMUR2 Antibody – Rabbit Polyclonal

Name: NMUR2 Antibody; Polyclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS242934
Price: 650 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS242934

Neuromedin U Receptor 2 is a Neuromedin Receptor. NMU2R may mediate the contractile activity of neuromedin U in the uterus. More details

$650 / 0.05 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

NMUR2, Polyclonal Antibody

Full Product Name

Rabbit Polyclonal to Human NMUR2

Product Gene Name

anti-NMUR2 antibody

Product Synonym Names

Anti-NMUR2 Antibody (C-Terminus) IHC-plus; NMUR2; FM-4; FM4; Neuromedin-U receptor 2; TGR1; Neuromedin u receptor-type 2; TGR-1; Neuromedin U receptor 2; NMU-R2; NMU2R; Human NMUR2

Clonality

Polyclonal

Host

Rabbit

Species Reactivity

Gorilla, Human
Predicted Reactivity: Gibbon (at least 90% immunogen sequence identity)

Form/Format

PBS, 0.1% sodium azide.

Purity/Purification

Immunoaffinity Purified

Concentration

1 mg/ml (lot specific)

Specificity

Human NMUR2. BLAST analysis of the peptide immunogen showed no homology with other human proteins.

Preparation and Storage

Long term: -70 degree C; Short term: +4 degree C

Molecular Weight

47,696 Da

OMIM

605108

3D Structure

ModBase 3D Structure for Q9GZQ4

Target Species

Human

Immunogen Description

Synthetic 19 amino acid peptide from C-terminus of human NMUR2. Percent identity with other species by BLAST analysis: Human, Gorilla (100%); Gibbon (95%); Marmoset, Panda, Dog, Horse (89%).

Immunogen Type

Synthetic peptide

Immunogen

NMUR2 antibody was raised against synthetic 19 amino acid peptide from C-terminus of human NMUR2. Percent identity with other species by BLAST analysis: Human, Gorilla (100%); Gibbon (95%); Marmoset, Panda, Dog, Horse (89%).

Antigen Modification

C-Terminus

Product Categories/Family for anti-NMUR2 antibody

Family: GPCR; Subfamily: Neuromedin

Applications Tested/Suitable for anti-NMUR2 antibody

Immunohistochemistry (IHC - Paraffin)

Application Notes for anti-NMUR2 antibody

IHC-P (6 ug/ml)

Other Notes

Small volumes of anti-NMUR2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for NMUR2 purchase

MBS242934 is an antibody targeting NMUR2. Also known as Rabbit Polyclonal to Human NMUR2. Reactive in Gorilla, Human
Predicted Reactivity: Gibbon (at least 90% immunogen sequence identity). Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for NMUR2. It may not necessarily be applicable to this product.

NCBI GI #

170932505

NCBI GeneID

56923

NCBI Accession #

NP_064552.3

UniProt Primary Accession #

Q9GZQ4

UniProt Secondary Accession #

Q7LC54; Q96AM5; Q9NRA6

UniProt Related Accession #

Q9GZQ4

GenBank Nucleotide #

NM_020167.4

NCBI Official Full Name

neuromedin-U receptor 2

NCBI Official Synonym Full Names

neuromedin U receptor 2

NCBI Official Symbol

NMUR2

NCBI Official Synonym Symbols

FM4; FM-4; TGR1; NMU2R; TGR-1; NMU-R2

UniProt Protein Name

Neuromedin-U receptor 2

UniProt Synonym Protein Names

G-protein coupled receptor FM-4; G-protein coupled receptor TGR-1

Protein Family

Neuromedin-U receptor

UniProt Gene Name

NMUR2

UniProt Synonym Gene Names

NMU2R; TGR1; NMU-R2

UniProt Entry Name

NMUR2_HUMAN

NCBI Protein Information

neuromedin-U receptor 2; G-protein coupled receptor FM-4; G-protein coupled receptor TGR-1; growth hormone secretagogue receptor family, member 4

NCBI Summary for NMUR2

This gene encodes a protein from the G-protein coupled receptor 1 family. This protein is a receptor for neuromedin U, which is a neuropeptide that is widely distributed in the gut and central nervous system. This receptor plays an important role in the regulation of food intake and body weight. [provided by RefSeq, Jul 2008]

UniProt Comments for NMUR2

NMUR2: Receptor for the neuromedin-U and neuromedin-S neuropeptides. Belongs to the G-protein coupled receptor 1 family.

Protein type: Receptor, GPCR; Membrane protein, integral; Membrane protein, multi-pass; GPCR, family 1

Chromosomal Location of Human Ortholog: 5q33.1

Cellular Component: plasma membrane; integral to membrane

Molecular Function: G-protein coupled receptor activity; GTP binding; intracellular calcium activated chloride channel activity; neuromedin U receptor activity; neuromedin U binding

Biological Process: regulation of smooth muscle contraction; grooming behavior; inositol phosphate-mediated signaling; central nervous system development; calcium-mediated signaling; chloride transport; response to pain; arachidonic acid secretion; reduction of food intake in response to dietary excess; elevation of cytosolic calcium ion concentration; cell-cell signaling; neuropeptide signaling pathway; calcium ion transport; calcium-dependent phospholipase A2 activation; G-protein signaling, coupled to IP3 second messenger (phospholipase C activating); feeding behavior

Research Articles on NMUR2

1. A cell-based reporter gene assay has been developed and used for the screening of the human NMU2R agonist.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-NMUR2 antibody

Reference Product	PubMed Publications
NMU antibody	>27 publications with NMUR2 and NMU
NMUR1 antibody	>22 publications with NMUR2 and NMUR1
NMS antibody	>7 publications with NMUR2 and NMS

Pathways associated with anti-NMUR2 antibody

Products by Pathway	Pathway Diagram
Class A/1 (Rhodopsin-like Receptors) Pathway antibodies	Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
Defective ACTH Causes Obesity And Pro-opiomelanocortinin Deficiency (POMCD) Pathway antibodies	Defective ACTH Causes Obesity And Pro-opiomelanocortinin Deficiency (POMCD) Pathway Diagram
Disease Pathway antibodies	Disease Pathway Diagram
G Alpha (i) Signalling Events Pathway antibodies	G Alpha (i) Signalling Events Pathway Diagram
G Alpha (q) Signalling Events Pathway antibodies	G Alpha (q) Signalling Events Pathway Diagram
GPCR Downstream Signaling Pathway antibodies	GPCR Downstream Signaling Pathway Diagram
GPCR Ligand Binding Pathway antibodies	GPCR Ligand Binding Pathway Diagram
GPCRs, Class A Rhodopsin-like Pathway antibodies	GPCRs, Class A Rhodopsin-like Pathway Diagram
Gastrin-CREB Signalling Pathway Via PKC And MAPK antibodies	Gastrin-CREB Signalling Pathway Via PKC And MAPK Diagram
Metabolic Disorders Of Biological Oxidation Enzymes Pathway antibodies	Metabolic Disorders Of Biological Oxidation Enzymes Pathway Diagram

Diseases associated with anti-NMUR2 antibody

Disease Name	Pubmed Publications
Weight Loss Antibodies	>4 publications with NMUR2 and Weight Loss
Eating Disorders Antibodies	>2 publications with NMUR2 and Eating Disorders
Hypertension Antibodies	>1 publications with NMUR2 and Hypertension

Organs/Tissues associated with anti-NMUR2 antibody

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>14 publications with NMUR2 and Brain
Testis Antibodies	>1 publications with NMUR2 and Testis
Heart Antibodies	>1 publications with NMUR2 and Heart