• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

LPHN3 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS242952

Latrophilin-3 is a brain-specific, Ca2+-independent Orphan-B Receptor with an unknown ligand. Unlike the other two latrophilins, Latrophilin-3 does not bind alpha-latrotoxin. Latrophilin-3, like its isoforms, shares homology with lectin, olfactomedin, and… More details

$630 / 0.05 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
LPHN3 / Latrophilin-3, Polyclonal Antibody
Full Product Name
Rabbit Polyclonal to Human LPHN3 / Latrophilin-3
Product Gene Name
anti-LPHN3 antibody
Product Synonym Names
Anti-LPHN3 / Latrophilin-3 Antibody (C-Terminus) IHC-plus; LPHN3; CIRL3; CIRL-3; Lectomedin 3; Lectomedin-3; Lph3; KIAA0768; Latrophilin 3; Latrophilin homolog 3 (cow); Cl3 latrotoxin receptor; Latrophilin-3; LEC3; Human LPHN3; Latrophilin-3
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Gibbon, Chicken, Gorilla, Hamster, Horse, Human, Monkey, Mouse, Rat
Form/Format
PBS, 0.1% sodium azide.
Purity/Purification
Immunoaffinity Purified
Concentration
1 mg/ml (lot specific)
Specificity
Human LPHN3. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Preparation and Storage
Long term: -70 degree C; Short term: +4 degree C
Molecular Weight
164,580 Da
3D Structure
ModBase 3D Structure for Q9HAR2
Target Species
Human
Immunogen Description
Synthetic 16 amino acid peptide from C-terminus of human LPHN3. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Hamster, Panda, Horse, Opossum, Turkey, Chicken, Platypus (100%).
Immunogen Type
Synthetic peptide
Immunogen
LPHN3 / Latrophilin-3 antibody was raised against synthetic 16 amino acid peptide from C-terminus of human LPHN3. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Hamster, Panda, Horse, Opossum, Turkey, Chicken, Platypus (100%); Zebrafish (88%); Pufferfish (81%).
Antigen Modification
C-Terminus

Product Categories/Family for anti-LPHN3 antibody

Family: GPCR; Subfamily: Orphan-B
Applications Tested/Suitable for anti-LPHN3 antibody
Immunohistochemistry (IHC - Paraffin)
Application Notes for anti-LPHN3 antibody
IHC-P (4 - 6 ug/ml)

Immunohistochemistry (IHC) of anti-LPHN3 antibody

Anti-Latrophilin-3 / LPHN3 antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 4-6 ug/ml.
Rabbit Anti-LPHN3 Polyclonal Antibody – Cat# MBS242952

Immunohistochemistry (IHC) of anti-LPHN3 antibody

Anti-Latrophilin-3 / LPHN3 antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 4-6 ug/ml.
Rabbit Anti-LPHN3 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS242952

Other Notes

Small volumes of anti-LPHN3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for LPHN3 purchase

MBS242952 is an antibody targeting LPHN3. Also known as Rabbit Polyclonal to Human LPHN3 / Latrophilin-3. Reactive in Gibbon, Chicken, Gorilla, Hamster, Horse, Human, Monkey, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for LPHN3. It may not necessarily be applicable to this product.

NCBI GI #
163792198
NCBI GeneID
23284
NCBI Accession #
NP_056051.2
UniProt Primary Accession #
Q9HAR2
UniProt Secondary Accession #
O94867; Q9NWK5; E9PE04
UniProt Related Accession #
Q9HAR2
GenBank Nucleotide #
NM_015236.4
NCBI Official Full Name
latrophilin-3
NCBI Official Synonym Full Names
latrophilin 3
NCBI Official Symbol
LPHN3
NCBI Official Synonym Symbols
LEC3; CIRL3
UniProt Protein Name
Latrophilin-3
UniProt Synonym Protein Names
Calcium-independent alpha-latrotoxin receptor 3; CIRL-3; Lectomedin-3
UniProt Gene Name
LPHN3
UniProt Synonym Gene Names
KIAA0768; LEC3; CIRL-3
UniProt Entry Name
LPHN3_HUMAN
NCBI Protein Information
latrophilin-3; CIRL-3; lectomedin 3; latrophilin homolog 3 (cow); calcium-independent alpha-latrotoxin receptor 3

NCBI Summary for LPHN3

This gene encodes a member of the latrophilin subfamily of G-protein coupled receptors (GPCR). Latrophilins may function in both cell adhesion and signal transduction. In experiments with non-human species, endogenous proteolytic cleavage within a cysteine-rich GPS (G-protein-coupled-receptor proteolysis site) domain resulted in two subunits (a large extracellular N-terminal cell adhesion subunit and a subunit with substantial similarity to the secretin/calcitonin family of GPCRs) being non-covalently bound at the cell membrane. [provided by RefSeq, Jul 2008]
Show more

UniProt Comments for LPHN3

latrophilin 3: a member of the latrophilin subfamily of G-protein coupled receptors (GPCR). Latrophilins may function in both cell adhesion and signal transduction. In experiments with non-human species, endogenous proteolytic cleavage within a cysteine-rich GPS (G-protein-coupled-receptor proteolysis site) domain resulted in two subunits (a large extracellular N-terminal cell adhesion subunit and a subunit with substantial similarity to the secretin/calcitonin family of GPCRs) being non-covalently bound at the cell membrane. [provided by RefSeq, Jul 2008]

Protein type: Membrane protein, multi-pass; GPCR, family 2; Receptor, GPCR; Membrane protein, integral

Chromosomal Location of Human Ortholog: 4q13.1

Cellular Component: integral to membrane; plasma membrane

Molecular Function: G-protein coupled receptor activity; carbohydrate binding

Biological Process: G-protein coupled receptor protein signaling pathway
Show more

Research Articles on LPHN3

1. genetic association studies in Germany: Data suggest that, within a sample of patients with attention deficit disorder hyperactivity, SNPs in LPHN3 gene impacts behavioral and neurophysiological measures of cognitive response control.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-LPHN3 antibody

 Reference Product  PubMed Publications
 GNAS antibody  >1 publications with LPHN3 and GNAS
 MAP2K4 antibody  >1 publications with LPHN3 and MAP2K4
 GNAO1 antibody  >1 publications with LPHN3 and GNAO1
 GRM8 antibody  >1 publications with LPHN3 and GRM8
 APLNR antibody  >1 publications with LPHN3 and APLNR

Pathways associated with anti-LPHN3 antibody

 Products by Pathway  Pathway Diagram
 GPCRs, Class B Secretin-like Pathway antibodies  GPCRs, Class B Secretin-like Pathway Diagram
 GPCRs, Other Pathway antibodies  GPCRs, Other Pathway Diagram

Diseases associated with anti-LPHN3 antibody

 Disease Name  Pubmed Publications
 Attention Deficit Disorder with Hyperactivity Antibodies  >20 publications with LPHN3 and Attention Deficit Disorder with Hyperactivity
 Nervous System Diseases Antibodies  >2 publications with LPHN3 and Nervous System Diseases
 Nerve Degeneration Antibodies  >1 publications with LPHN3 and Nerve Degeneration
 Brain Diseases Antibodies  >1 publications with LPHN3 and Brain Diseases
 Lung Diseases Antibodies  >1 publications with LPHN3 and Lung Diseases
 Prenatal Injuries Antibodies  >1 publications with LPHN3 and Prenatal Injuries
 Cognition Disorders Antibodies  >1 publications with LPHN3 and Cognition Disorders
 Prenatal Exposure Delayed Effects Antibodies  >1 publications with LPHN3 and Prenatal Exposure Delayed Effects

Organs/Tissues associated with anti-LPHN3 antibody

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >14 publications with LPHN3 and Brain
 Eye Antibodies  >1 publications with LPHN3 and Eye
 Placenta Antibodies  >1 publications with LPHN3 and Placenta
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000