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GPR64 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS242978

GPR64 is an Orphan-B GPCR with an unknown ligand. HE6 is endogenously cleaved into two pieces at the GPCR proteolytic site (GPS) located adjacent to the first transmembrane helix as a mechanism to compartmentalize the cell adhesion and GPCR activation… More details

$650 / 0.05 mg +1 FREE 8GB USB
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Sample Manual Insert View PDF
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Testing Data View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
GPR64, Polyclonal Antibody
Full Product Name
Rabbit Polyclonal to Human GPR64
Product Gene Name
Product Synonym Names
Anti-GPR64 Antibody (C-Terminus) IHC-plus; GPR64; Epididymal protein 6; G protein-coupled receptor 64; EDDM6; G-protein coupled receptor 64; HE6; TM7LN2; Human GPR64
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Gibbon, Gorilla, Hamster, Human, Monkey, Mouse, Rat
Predicted Reactivity: Bat, Bovine, Dog, Horse, Rabbit (at least 90% immunogen sequence identity)
Form/Format
PBS, 0.1% sodium azide.
Purity/Purification
Immunoaffinity Purified
Concentration
1 mg/ml (lot specific)
Specificity
Human GPR64. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Preparation and Storage
Long term: -70 degree C; Short term: +4 degree C
Molecular Weight
98,720 Da
OMIM
300572
3D Structure
ModBase 3D Structure for Q8IZP9
Target Species
Human
Immunogen Description
Synthetic 20 amino acid peptide from C-terminus of human GPR64. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Hamster, Elephant, Opossum (100%); Bovine, Panda, Rabbit (95%).
Immunogen Type
Synthetic peptide
Immunogen
GPR64 antibody was raised against synthetic 20 amino acid peptide from C-terminus of human GPR64. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Hamster, Elephant, Opossum (100%); Bovine, Panda, Rabbit (95%); Dog, Bat, Horse (90%); Pig, Platypus (80%).
Antigen Modification
C-Terminus
Applications Tested/Suitable for anti-GPR64 antibody
Immunohistochemistry (IHC - Paraffin)
Application Notes for anti-GPR64 antibody
IHC-P (5 ug/ml)

Immunohistochemistry (IHC) of anti-GPR64 antibody

Anti-GPR64 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Rabbit Anti-GPR64 Polyclonal Antibody – Cat# MBS242978

Immunohistochemistry (IHC) of anti-GPR64 antibody

Anti-GPR64 antibody IHC of human Skin, Melanoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Rabbit Anti-GPR64 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS242978

Immunohistochemistry (IHC) of anti-GPR64 antibody

Anti-GPR64 antibody IHC of human Brain, Glioblastoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Rabbit Anti-GPR64 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS242978

Other Notes

Small volumes of anti-GPR64 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for GPR64 purchase

MBS242978 is an antibody targeting GPR64. Also known as Rabbit Polyclonal to Human GPR64. Reactive in Gibbon, Gorilla, Hamster, Human, Monkey, Mouse, Rat
Predicted Reactivity: Bat, Bovine, Dog, Horse, Rabbit (at least 90% immunogen sequence identity). Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for GPR64. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
G-protein coupled receptor 64 isoform 4
NCBI Official Synonym Full Names
G protein-coupled receptor 64
NCBI Official Symbol
GPR64
NCBI Official Synonym Symbols
HE6; EDDM6; TM7LN2
UniProt Protein Name
G-protein coupled receptor 64
UniProt Synonym Protein Names
Human epididymis-specific protein 6; He6
UniProt Gene Name
GPR64
UniProt Synonym Gene Names
HE6; TM7LN2; He6
UniProt Entry Name
GPR64_HUMAN
NCBI Protein Information
G-protein coupled receptor 64; epididymal protein 6; human epididymis-specific protein 6; G protein-coupled receptor, epididymis-specific (seven transmembrane family)

NCBI Summary for GPR64

This gene encodes a member of the G protein-coupled receptor family described as an epididymis-specific transmembrane protein. The encoded protein may be proteolytically processed as it contains a motif shown to be a protein scission motif in some members of this family (PMID: 11973329). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011]
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UniProt Comments for GPR64

GPR64: Could be involved in a signal transduction pathway controlling epididymal function and male fertility. Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily. 9 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, multi-pass; GPCR, family 2; Membrane protein, integral; Receptor, GPCR

Chromosomal Location of Human Ortholog: Xp22.13

Cellular Component: cell surface; integral to plasma membrane; apical plasma membrane; integral to membrane

Molecular Function: G-protein coupled receptor activity

Biological Process: G-protein coupled receptor protein signaling pathway; spermatogenesis
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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