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CDHR5 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS243026

Mucin-like protocadherin is a developmentally regulated cell adhesion molecule that contains an extracellular region with four cadherin-like ectodomains and a triply repeating mucin domain in its' longer isoform. This later domain is known to negatively… More details

$630 / 0.05 mg +1 FREE 8GB USB
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Product Overview

Online Datasheet in PDF
Product Name
CDHR5 / MUCDHL, Polyclonal Antibody
Full Product Name
Rabbit Polyclonal to Human CDHR5 / MUCDHL
Product Gene Name
Product Synonym Gene Name
MUCDHL
Product Synonym Names
Anti-CDHR5 / MUCDHL Antibody (Internal) IHC-plus; CDHR5; Mu-protocadherin; Mucin and cadherin-like; MUPCDH; Mucin-like protocadherin; MU-PCDH; MUCDHL; MUCDHL-ALT; MUCDHL-FL; Human CDHR5; MUCDHL
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human
Predicted Reactivity: Monkey (at least 90% immunogen sequence identity)
Form/Format
PBS, 0.1% sodium azide.
Purity/Purification
Immunoaffinity Purified
Concentration
1 mg/ml (lot specific)
Specificity
Human CDHR5 / MUPCDH. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Preparation and Storage
Long term: -70 degree C; Short term: +4 degree C
Molecular Weight
87,631 Da
OMIM
606839
3D Structure
ModBase 3D Structure for Q9HBB8
Target Species
Human
Immunogen Description
Synthetic 17 amino acid peptide from internal region of human CDHR5 / MUPCDH. Percent identity with other species by BLAST analysis: Human (100%); Monkey, Panda (94%); Gorilla, Orangutan, Marmoset (88%); Mouse, Horse (82%).
Immunogen Type
Synthetic peptide
Immunogen
CDHR5 / MUCDHL antibody was raised against synthetic 17 amino acid peptide from internal region of human CDHR5 / MUPCDH. Percent identity with other species by BLAST analysis: Human (100%); Monkey, Panda (94%); Gorilla, Orangutan, Marmoset (88%); Mouse, Horse (82%).
Antigen Modification
Internal

Product Categories/Family for anti-CDHR5 antibody

Applications Tested/Suitable for anti-CDHR5 antibody
Immunohistochemistry (IHC - Paraffin)
Application Notes for anti-CDHR5 antibody
IHC-P (10 ug/ml)
Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary anti...

Immunohistochemistry (IHC) of anti-CDHR5 antibody

Anti-CDHR5 / MUPCDH antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Rabbit Anti-CDHR5 Polyclonal Antibody – Cat# MBS243026

Immunohistochemistry (IHC) of anti-CDHR5 antibody

Anti-CDHR5 / MUPCDH antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Rabbit Anti-CDHR5 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS243026

Other Notes

Small volumes of anti-CDHR5 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CDHR5 purchase

MBS243026 is an antibody targeting CDHR5. Also known as Rabbit Polyclonal to Human CDHR5 / MUCDHL. Reactive in Human
Predicted Reactivity: Monkey (at least 90% immunogen sequence identity). Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for CDHR5. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
cadherin-related family member 5 isoform 1
NCBI Official Synonym Full Names
cadherin-related family member 5
NCBI Official Symbol
CDHR5
NCBI Official Synonym Symbols
MUCDHL; MUPCDH; MU-PCDH
UniProt Protein Name
Cadherin-related family member 5
UniProt Synonym Protein Names
Mu-protocadherin; Mucin and cadherin-like protein
UniProt Gene Name
CDHR5
UniProt Synonym Gene Names
MUCDHL; MUPCDH
UniProt Entry Name
CDHR5_HUMAN
NCBI Protein Information
cadherin-related family member 5; mu-protocadherin; mucin and cadherin-like protein

NCBI Summary for CDHR5

This gene is a novel mucin-like gene that is a member of the cadherin superfamily. While encoding nonpolymorphic tandem repeats rich in proline, serine and threonine similar to mucin proteins, the gene also contains sequence encoding calcium-binding motifs found in all cadherins. The role of the hybrid extracellular region and the specific function of this protein have not yet been determined. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jan 2010]
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UniProt Comments for CDHR5

MUCDHL: Acts as a calcium-dependent cell adhesion protein. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Motility/polarity/chemotaxis; Cell adhesion

Chromosomal Location of Human Ortholog: 11p15.5

Cellular Component: integral to membrane; plasma membrane

Molecular Function: protein binding; beta-catenin binding; calcium ion binding

Biological Process: cell adhesion; homophilic cell adhesion
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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