Rabbit Anti-GPR84 Polyclonal Antibody – Cat# MBS243057

Human, Spleen: Formalin-Fixed Paraffin-Embedded (FFPE)

GPR84 Antibody – Rabbit Polyclonal

Name: GPR84 Antibody; Polyclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS243057
Price: 630 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS243057

MBS243057 is an antibody targeting GPR84. Also known as Rabbit Polyclonal to Human GPR84. Reactive in Gorilla, Horse, Human, MonkeyPredicted Reactivity: Gibbon (at least 90% immunogen sequence identity). Host: Rabbit. G protein-coupled receptor EX33 is an… More details

$630 / 0.05 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

GPR84, Polyclonal Antibody

Full Product Name

Rabbit Polyclonal to Human GPR84

Product Gene Name

anti-GPR84 antibody

Product Synonym Names

Anti-GPR84 Antibody (Extracellular Domain) IHC-plus; GPR84; EX33; GPCR4; G-protein coupled receptor 84; G protein-coupled receptor 84; Human GPR84

Clonality

Polyclonal

Host

Rabbit

Species Reactivity

Gorilla, Horse, Human, Monkey
Predicted Reactivity: Gibbon (at least 90% immunogen sequence identity)

Form/Format

PBS, 0.1% sodium azide.

Purity/Purification

Immunoaffinity Purified

Concentration

1 mg/ml (lot specific)

Specificity

Human GPR84. BLAST analysis of the peptide immunogen showed no homology with other human proteins.

Preparation and Storage

Long term: -70 degree C; Short term: +4 degree C

Molecular Weight

43,705 Da

OMIM

606383

3D Structure

ModBase 3D Structure for Q9NQS5

Target Species

Human

Immunogen Description

Synthetic 19 amino acid peptide from 2nd extracellular domain of human GPR84. Percent identity with other species by BLAST analysis: Human, Gorilla, Monkey, Marmoset, Horse (100%); Gibbon (95%); Elephant, Bovine, Rabbit (89%); Mouse, Dog (84%).

Immunogen Type

Synthetic peptide

Immunogen

GPR84 antibody was raised against synthetic 19 amino acid peptide from 2nd extracellular domain of human GPR84. Percent identity with other species by BLAST analysis: Human, Gorilla, Monkey, Marmoset, Horse (100%); Gibbon (95%); Elephant, Bovine, Rabbit (89%); Mouse, Dog (84%).

Antigen Modification

Extracellular Domain

Product Categories/Family for anti-GPR84 antibody

Family: GPCR; Subfamily: Orphan-A

Applications Tested/Suitable for anti-GPR84 antibody

Immunohistochemistry (IHC - Paraffin)

Application Notes for anti-GPR84 antibody

IHC-P

Other Notes

Small volumes of anti-GPR84 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for GPR84. It may not necessarily be applicable to this product.

NCBI GI #

9966839

NCBI GeneID

53831

NCBI Accession #

NP_065103.1

UniProt Primary Accession #

Q9NQS5

UniProt Secondary Accession #

B6V9G7

UniProt Related Accession #

Q9NQS5

GenBank Nucleotide #

NM_020370.2

NCBI Official Full Name

G-protein coupled receptor 84

NCBI Official Synonym Full Names

G protein-coupled receptor 84

NCBI Official Symbol

GPR84

NCBI Official Synonym Symbols

EX33; GPCR4

UniProt Protein Name

G-protein coupled receptor 84

UniProt Synonym Protein Names

Inflammation-related G-protein coupled receptor EX33

Protein Family

G-protein coupled receptor

UniProt Gene Name

GPR84

UniProt Synonym Gene Names

EX33

UniProt Entry Name

GPR84_HUMAN

NCBI Protein Information

G-protein coupled receptor 84; inflammation-related G protein-coupled receptor EX33; inflammation-related G-protein coupled receptor EX33

UniProt Comments for GPR84

GPR84: Receptor for medium-chain free fatty acid (FFA) with carbon chain lengths of C9 to C14. Capric acid (C10:0), undecanoic acid (C11:0) and lauric acid (C12:0) are the most potent agonists. Not activated by short-chain and long-chain saturated and unsaturated FFAs. Activation by medium-chain free fatty acid is coupled to a pertussis toxin sensitive G(i/o) protein pathway. May have important roles in processes from fatty acid metabolism to regulation of the immune system. Belongs to the G-protein coupled receptor 1 family.

Protein type: Motility/polarity/chemotaxis; Membrane protein, integral; Membrane protein, multi-pass; GPCR, family 1; Receptor, GPCR

Chromosomal Location of Human Ortholog: 12q13.13

Cellular Component: plasma membrane; integral to membrane; receptor complex

Molecular Function: G-protein coupled receptor activity

Biological Process: G-protein coupled receptor protein signaling pathway

Research Articles on GPR84

1. Medium-chain fatty acid-sensing receptor, GPR84, is a proinflammatory receptor.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-GPR84 antibody

Reference Product	PubMed Publications
FFAR1 antibody	>3 publications with GPR84 and FFAR1

Pathways associated with anti-GPR84 antibody

Products by Pathway	Pathway Diagram
GPCRs, Other Pathway antibodies	GPCRs, Other Pathway Diagram

Diseases associated with anti-GPR84 antibody

Disease Name	Pubmed Publications
Inflammation Antibodies	>10 publications with GPR84 and Inflammation
Necrosis Antibodies	>3 publications with GPR84 and Necrosis
Demyelinating Diseases Antibodies	>1 publications with GPR84 and Demyelinating Diseases
Nervous System Diseases Antibodies	>1 publications with GPR84 and Nervous System Diseases
Fatty Liver Antibodies	>1 publications with GPR84 and Fatty Liver
Kidney Diseases Antibodies	>1 publications with GPR84 and Kidney Diseases
Disease Models, Animal Antibodies	>1 publications with GPR84 and Disease Models, Animal

Organs/Tissues associated with anti-GPR84 antibody

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>7 publications with GPR84 and Blood
Bone Marrow Antibodies	>4 publications with GPR84 and Bone Marrow
Intestine Antibodies	>3 publications with GPR84 and Intestine
Brain Antibodies	>3 publications with GPR84 and Brain
Eye Antibodies	>1 publications with GPR84 and Eye
Lung Antibodies	>1 publications with GPR84 and Lung