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TSC22D1 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS243171

MBS243171 is an antibody targeting TSC22D1. Also known as Rabbit Polyclonal (IgG) to Human TSC22D1 / TSC22. Reactive in Human, Mouse, Rat. Host: Rabbit. More details

$650 / 0.05 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
TSC22D1 / TSC22, Polyclonal Antibody
Full Product Name
Rabbit Polyclonal (IgG) to Human TSC22D1 / TSC22
Product Gene Name
Product Synonym Gene Name
TSC22
Product Synonym Names
Anti-TSC22D1 / TSC22 Antibody (aa71-120) IHC-plus; TSC22D1; Cerebral protein 2; Ptg-2; Regulatory protein TSC-22; TSC22 domain family protein 1; TGFB1I4; TSC22; TSC22 domain family; member 1; KIAA1994; TGFbeta-stimulated clone 22; Human TSC22D1; TSC22
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
PBS (without Mg2+, Ca2+), pH 7.4, 150 mM sodium chloride, 0.02% sodium azide, 50% glycerol
Purity/Purification
Immunoaffinity Purified
Concentration
1 mg/ml (lot specific)
Specificity
TSC22D1 Antibody detects endogenous levels of total TSC22D1 protein.
Preparation and Storage
Store at -20 degree C for up to one year.
Molecular Weight
58,859 Da
OMIM
607715
3D Structure
ModBase 3D Structure for Q15714
Target Species
Human
Immunogen Description
Synthetic peptide from human TSC22D1 (aa71-120).
Immunogen
TSC22D1 / TSC22 antibody was raised against synthetic peptide from human TSC22D1 (aa71-120).
Antigen Modification
aa71-120
Applications Tested/Suitable for anti-TSC22D1 antibody
Immunohistochemistry (IHC - Paraffin), Immunofluorescence (IF), Western Blot (WB), ELISA (EIA)
Application Notes for anti-TSC22D1 antibody
ELISA (1:20000), IF (1:100 - 1:500), IHC-P (5 ug/ml), WB (1:500 - 1:1000)

Immunohistochemistry (IHC) of anti-TSC22D1 antibody

Anti-TSC22 antibody IHC of human lung. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 5 ug/ml.
Rabbit Anti-TSC22D1 Polyclonal Antibody – Cat# MBS243171

Immunofluorescence (IF) of anti-TSC22D1 antibody

Immunofluorescence of HepG2 cells, using TSC22D1 Antibody. The picture on the right is treated with the synthesized peptide.
Rabbit Anti-TSC22D1 Polyclonal Antibody, Immunofluorescence (IF) – Cat# MBS243171

Western Blot (WB) of anti-TSC22D1 antibody

Western blot of extracts from mouse liver/rat liver cells, using TSC22D1 Antibody. The lane on the right is treated with the synthesized peptide.
Rabbit Anti-TSC22D1 Polyclonal Antibody, Western Blot (WB) – Cat# MBS243171

Other Notes

Small volumes of anti-TSC22D1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for TSC22D1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
TSC22 domain family protein 1 isoform 2
NCBI Official Synonym Full Names
TSC22 domain family, member 1
NCBI Official Symbol
TSC22D1
NCBI Official Synonym Symbols
Ptg-2; TSC22; TGFB1I4
UniProt Protein Name
TSC22 domain family protein 1
UniProt Synonym Protein Names
Cerebral protein 2; Regulatory protein TSC-22; TGFB-stimulated clone 22 homolog; Transforming growth factor beta-1-induced transcript 4 protein
UniProt Gene Name
TSC22D1
UniProt Synonym Gene Names
KIAA1994; TGFB1I4; TSC22
UniProt Entry Name
T22D1_HUMAN
NCBI Protein Information
TSC22 domain family protein 1; cerebral protein 2; regulatory protein TSC-22; TGFbeta-stimulated clone 22; TGFB-stimulated clone 22 homolog; transcriptional regulator TSC-22; transforming growth factor beta-stimulated protein TSC-22; transforming growth factor beta-1-induced transcript 4 protein

NCBI Summary for TSC22D1

This gene encodes a member of the TSC22 domain family of leucine zipper transcription factors. The encoded protein is stimulated by transforming growth factor beta, and regulates the transcription of multiple genes including C-type natriuretic peptide. The encoded protein may play a critical role in tumor suppression through the induction of cancer cell apoptosis, and a single nucleotide polymorphism in the promoter of this gene has been associated with diabetic nephropathy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Aug 2011]
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UniProt Comments for TSC22D1

TSC22D1: Transcriptional repressor. Acts on the C-type natriuretic peptide (CNP) promoter. Belongs to the TSC-22/Dip/Bun family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: DNA-binding; Transcription factor

Chromosomal Location of Human Ortholog: 13q14

Cellular Component: cytoplasm; nucleus

Molecular Function: protein binding; transcription factor activity

Biological Process: transcription from RNA polymerase II promoter; regulation of transcription, DNA-dependent; positive regulation of apoptosis; positive regulation of cell proliferation; negative regulation of apoptosis
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-TSC22D1 antibody

 Reference Product  PubMed Publications
 TSC22D4 antibody  >2 publications with TSC22D1 and TSC22D4
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