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AVPR1B Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS243197

The vasopressin V1B receptor is a member of the Vasopressin/Oxytocin Family subfamily. The V1B receptor is expressed specifically in pituitary corticotropes and mediates the stimulatory effect of vasopressin on adrenocorticotropic hormone (ACTH) release. More details

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Product Overview

Online Datasheet in PDF
Product Name
AVPR1B, Polyclonal Antibody
Full Product Name
Rabbit Polyclonal to Human AVPR1B
Product Gene Name
anti-AVPR1B antibody
Product Synonym Names
Anti-AVPR1B Antibody (C-Terminus) IHC-plus; AVPR1B; AVPR3; V1bR; AVPR V1b; AVPR V3; V1b receptor; V1b vasopressin receptor; Vasopressin V1b receptor; Vasopressin V3 receptor; VPR3; Human AVPR1B
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Gibbon, Gorilla, Human
Form/Format
PBS, 0.1% sodium azide.
Purity/Purification
Immunoaffinity Purified
Concentration
1 mg/ml (lot specific)
Specificity
Human AVPR1B. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Preparation and Storage
Long term: -70 degree C; Short term: +4 degree C
Molecular Weight
46,971 Da
OMIM
600264
3D Structure
ModBase 3D Structure for P47901
Target Species
Human
Immunogen Description
Synthetic 19 amino acid peptide from C-terminus of human AVPR1B. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon (100%); Monkey, Marmoset (89%); Bovine (84%).
Immunogen Type
Synthetic peptide
Immunogen
AVPR1B antibody was raised against synthetic 19 amino acid peptide from C-terminus of human AVPR1B. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon (100%); Monkey, Marmoset (89%); Bovine (84%).
Antigen Modification
C-Terminus

Product Categories/Family for anti-AVPR1B antibody

Family: GPCR; Subfamily: Vasopressin/oxytocin
Applications Tested/Suitable for anti-AVPR1B antibody
Immunohistochemistry (IHC - Paraffin)
Application Notes for anti-AVPR1B antibody
IHC-P (2 - 7 ug/ml)

Immunohistochemistry (IHC) of anti-AVPR1B antibody

Anti-AVPR1B antibody IHC of human pancreas islet of Langerhans. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Rabbit Anti-AVPR1B Polyclonal Antibody – Cat# MBS243197

Immunohistochemistry (IHC) of anti-AVPR1B antibody

Anti-AVPR1B antibody IHC of human Skin, Melanoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Rabbit Anti-AVPR1B Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS243197

Immunohistochemistry (IHC) of anti-AVPR1B antibody

Anti-AVPR1B antibody IHC of human malignant melanoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 2-7 ug/ml.
Rabbit Anti-AVPR1B Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS243197

Immunohistochemistry (IHC) of anti-AVPR1B antibody

Anti-AVPR1B antibody IHC of human pituitary. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 2-7 ug/ml.
Rabbit Anti-AVPR1B Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS243197

Immunohistochemistry (IHC) of anti-AVPR1B antibody

Anti-AVPR1B antibody IHC of human Prostate, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Rabbit Anti-AVPR1B Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS243197

Other Notes

Small volumes of anti-AVPR1B antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for AVPR1B purchase

MBS243197 is an antibody targeting AVPR1B. Also known as Rabbit Polyclonal to Human AVPR1B. Reactive in Gibbon, Gorilla, Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for AVPR1B. It may not necessarily be applicable to this product.

NCBI GI #
4502333
NCBI GeneID
553
NCBI Accession #
NP_000698.1
UniProt Primary Accession #
P47901
UniProt Secondary Accession #
Q5TZ00; B0M0J6
UniProt Related Accession #
P47901
GenBank Nucleotide #
NM_000707.3
NCBI Official Full Name
vasopressin V1b receptor
NCBI Official Synonym Full Names
arginine vasopressin receptor 1B
NCBI Official Symbol
AVPR1B
NCBI Official Synonym Symbols
AVPR3
UniProt Protein Name
Vasopressin V1b receptor
UniProt Synonym Protein Names
AVPR V1b; AVPR V3; Antidiuretic hormone receptor 1b; Vasopressin V3 receptor
Protein Family
Vasopressin V1b receptor
UniProt Gene Name
AVPR1B
UniProt Synonym Gene Names
AVPR3; VPR3; V1bR
UniProt Entry Name
V1BR_HUMAN
NCBI Protein Information
vasopressin V1b receptor; V1bR; AVPR V3; AVPR V1b; vasopressin V3 receptor; arginine vasopressin receptor 3; antidiuretic hormone receptor 1B; pituitary vasopressin receptor 3

NCBI Summary for AVPR1B

The protein encoded by this gene acts as receptor for arginine vasopressin. This receptor belongs to the subfamily of G-protein coupled receptors which includes AVPR1A, V2R and OXT receptors. Its activity is mediated by G proteins which stimulate a phosphatidylinositol-calcium second messenger system. The receptor is primarily located in the anterior pituitary, where it stimulates ACTH release. It is expressed at high levels in ACTH-secreting pituitary adenomas as well as in bronchial carcinoids responsible for the ectopic ACTH syndrome. A spliced antisense transcript of this gene has been reported but its function is not known. [provided by RefSeq, Jul 2008]
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UniProt Comments for AVPR1B

AVPR1B: Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.

Protein type: GPCR, family 1; Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCR

Chromosomal Location of Human Ortholog: 1q32

Cellular Component: integral to plasma membrane; plasma membrane; endosome

Molecular Function: protein kinase C binding; peptide binding; vasopressin receptor activity

Biological Process: G-protein coupled receptor protein signaling pathway; elevation of cytosolic calcium ion concentration; regulation of systemic arterial blood pressure by vasopressin; phospholipase C activation; positive regulation of vasoconstriction; cellular response to hormone stimulus
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Research Articles on AVPR1B

1. association between polymorphisms of AVPR1b gene and psychotic dimension.possible involvement of the AVPR1b gene in the etiology of psychotic features in the course of affective disorders

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-AVPR1B antibody

 Reference Product  PubMed Publications
 AVPR1A antibody  >7019 publications with AVPR1B and AVPR1A
 OXT antibody  >68 publications with AVPR1B and OXT
 NTS antibody  >49 publications with AVPR1B and NTS
 TRH antibody  >33 publications with AVPR1B and TRH
 GRP antibody  >20 publications with AVPR1B and GRP
 GRK5 antibody  >4 publications with AVPR1B and GRK5
 GNRH1 antibody  >1 publications with AVPR1B and GNRH1
 AGTR1 antibody  >1 publications with AVPR1B and AGTR1

Pathways associated with anti-AVPR1B antibody

 Products by Pathway  Pathway Diagram
 Calcium Signaling Pathway antibodies  Calcium Signaling Pathway Diagram
 Calcium Signaling Pathway antibodies  Calcium Signaling Pathway Diagram
 Class A/1 (Rhodopsin-like Receptors) Pathway antibodies  Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
 Defective ACTH Causes Obesity And Pro-opiomelanocortinin Deficiency (POMCD) Pathway antibodies  Defective ACTH Causes Obesity And Pro-opiomelanocortinin Deficiency (POMCD) Pathway Diagram
 Disease Pathway antibodies  Disease Pathway Diagram
 G Alpha (q) Signalling Events Pathway antibodies  G Alpha (q) Signalling Events Pathway Diagram
 GPCR Downstream Signaling Pathway antibodies  GPCR Downstream Signaling Pathway Diagram
 GPCR Ligand Binding Pathway antibodies  GPCR Ligand Binding Pathway Diagram
 GPCRs, Class A Rhodopsin-like Pathway antibodies  GPCRs, Class A Rhodopsin-like Pathway Diagram
 Gastrin-CREB Signalling Pathway Via PKC And MAPK antibodies  Gastrin-CREB Signalling Pathway Via PKC And MAPK Diagram

Diseases associated with anti-AVPR1B antibody

 Disease Name  Pubmed Publications
 Kidney Diseases Antibodies  >469 publications with AVPR1B and Kidney Diseases
 Nervous System Diseases Antibodies  >331 publications with AVPR1B and Nervous System Diseases
 Inflammation Antibodies  >102 publications with AVPR1B and Inflammation
 Edema Antibodies  >74 publications with AVPR1B and Edema
 Hypertrophy Antibodies  >64 publications with AVPR1B and Hypertrophy
 Body Weight Changes Antibodies  >55 publications with AVPR1B and Body Weight Changes
 Hyperplasia Antibodies  >48 publications with AVPR1B and Hyperplasia
 Necrosis Antibodies  >39 publications with AVPR1B and Necrosis
 Memory Disorders Antibodies  >32 publications with AVPR1B and Memory Disorders
 Weight Loss Antibodies  >29 publications with AVPR1B and Weight Loss

Organs/Tissues associated with anti-AVPR1B antibody

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >2557 publications with AVPR1B and Brain
 Mixed Antibodies  >65 publications with AVPR1B and Mixed
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