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SNX12 Antibody – Goat Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS243209

MBS243209 is an antibody targeting SNX12. Also known as Goat Polyclonal to Human SNX12. Reactive in Bat, Gibbon, Bovine, Gorilla, Hamster, Human, Monkey, Mouse, Pig, RabbitPredicted Reactivity: Chicken, Xenopus (at least 90% immunogen sequence identity).… More details

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Product Overview

Product Name
SNX12, Polyclonal Antibody
Full Product Name
Goat Polyclonal to Human SNX12
Product Gene Name
Product Synonym Names
Anti-SNX12 Antibody (C-Terminus) IHC-plus; SNX12; Sorting nexin 12; Sorting nexin-12; Human SNX12
Clonality
Polyclonal
Host
Goat
Species Reactivity
Bat, Gibbon, Bovine, Gorilla, Hamster, Human, Monkey, Mouse, Pig, Rabbit
Predicted Reactivity: Chicken, Xenopus (at least 90% immunogen sequence identity)
Form/Format
Tris-buffered saline, pH 7.3, 0.5% BSA, 0.02% sodium azide
Purity/Purification
Immunoaffinity Purified
Concentration
0.5 mg/ml (lot specific)
Specificity
Human SNX12.
Preparation and Storage
Store at -20 degree C. Minimize freezing and thawing.
Molecular Weight
18,342 Da
OMIM
300883
3D Structure
ModBase 3D Structure for Q9UMY4
Target Species
Human
Immunogen Description
Synthetic peptide C-AIDRNYVPGKVRQ from the C-terminus of human SNX12 (NP_037478.2). Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Hamster, Elephant, Bovine, Bat, Rabbit, Pig (100%).
Immunogen Type
Synthetic peptide
Immunogen
SNX12 antibody was raised against synthetic peptide C-AIDRNYVPGKVRQ from the C-terminus of human SNX12 (NP_037478.2). Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Hamster, Elephant, Bovine, Bat, Rabbit, Pig (100%); Opossum, Turkey, Chicken, Xenopus (92%); Rat, Zebrafish (85%).
Antigen Modification
C-Terminus
Applications Tested/Suitable for anti-SNX12 antibody
Immunohistochemistry (IHC - Paraffin), ELISA (EIA)
Application Notes for anti-SNX12 antibody
ELISA (1:32000), IHC-P (3.75 ug/ml)

Immunohistochemistry (IHC) of anti-SNX12 antibody

Anti-SNX12 antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 3.75 ug/ml.
Goat Anti-SNX12 Polyclonal Antibody – Cat# MBS243209

Immunohistochemistry (IHC) of anti-SNX12 antibody

Anti-SNX12 antibody IHC of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 3.75 ug/ml.
Goat Anti-SNX12 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS243209

Other Notes

Small volumes of anti-SNX12 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for SNX12. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
sorting nexin-12 isoform 1
NCBI Official Synonym Full Names
sorting nexin 12
NCBI Official Symbol
SNX12
UniProt Protein Name
Sorting nexin-12
Protein Family
UniProt Gene Name
SNX12
UniProt Entry Name
SNX12_HUMAN
NCBI Protein Information
sorting nexin-12

NCBI Summary for SNX12

This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein does not contain a coiled coil region, like some family members. A similar protein in mouse may be involved in regulating the neurite outgrowth. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2012]
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UniProt Comments for SNX12

SNX12: May be involved in several stages of intracellular trafficking. Belongs to the sorting nexin family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Vesicle

Chromosomal Location of Human Ortholog: Xq13.1

Cellular Component: extrinsic to membrane; early endosome; endosome

Molecular Function: protein binding; enzyme binding; phosphoinositide binding

Biological Process: protein transport; vesicle organization and biogenesis; regulation of endocytosis; endocytosis; negative regulation of protein transport; negative regulation of protein catabolic process
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with anti-SNX12 antibody

Organs/Tissues associated with anti-SNX12 antibody

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >2 publications with SNX12 and Brain
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