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SLITRK6 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS243245

SLITEK6 is a member of the SLITRK (SLIT-and NTRK-like Famliy) family of proteins. These proteins are primarily expressed in brain and control neurite outgrowth. SLITEK6 is an integral membrane protein with 2 N-terminal leucine-rich repeats (LRR) domains and a… More details

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Product Overview

Online Datasheet in PDF
Product Name
SLITRK6, Polyclonal Antibody
Full Product Name
Rabbit Polyclonal to Human SLITRK6
Product Gene Name
Product Synonym Names
Anti-SLITRK6 Antibody (Internal) IHC-plus; SLITRK6; Slit and trk like gene 6; SLIT and NTRK-like protein 6; Human SLITRK6
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Gibbon, Chimpanzee, Hamster, Human, Rat
Predicted Reactivity: Gorilla, Monkey, Mouse, Pig (at least 90% immunogen sequence identity)
Form/Format
PBS, 0.1% sodium azide.
Purity/Purification
Immunoaffinity Purified
Concentration
1 mg/ml (lot specific)
Specificity
Human SLITRK6. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Preparation and Storage
Long term: -70 degree C; Short term: +4 degree C
Molecular Weight
95,110 Da
OMIM
phenotype 609681
3D Structure
ModBase 3D Structure for Q9H5Y7
Target Species
Human
Immunogen Description
Synthetic 16 amino acid peptide from internal region of human SLITRK6. Percent identity with other species by BLAST analysis: Human, Chimpanzee, Gibbon, Monkey, Rat, Hamster (100%); Gorilla, Galago, Marmoset, Mouse, Elephant, Pig (94%).
Immunogen Type
Synthetic peptide
Immunogen
SLITRK6 antibody was raised against synthetic 16 amino acid peptide from internal region of human SLITRK6. Percent identity with other species by BLAST analysis: Human, Chimpanzee, Gibbon, Monkey, Rat, Hamster (100%); Gorilla, Galago, Marmoset, Mouse, Elephant, Pig (94%); Panda, Bovine, Bat, Dog, Horse, Zebra finch, Chicken (88%); Opossum, Turkey (81%).
Antigen Modification
Internal
Applications Tested/Suitable for anti-SLITRK6 antibody
Immunohistochemistry (IHC - Paraffin)
Application Notes for anti-SLITRK6 antibody
IHC-P (15 ug/ml)
Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary anti...

Immunohistochemistry (IHC) of anti-SLITRK6 antibody

Anti-SLITRK6 antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Rabbit Anti-SLITRK6 Polyclonal Antibody – Cat# MBS243245

Immunohistochemistry (IHC) of anti-SLITRK6 antibody

Anti-SLITRK6 antibody IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Rabbit Anti-SLITRK6 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS243245

Other Notes

Small volumes of anti-SLITRK6 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SLITRK6 purchase

MBS243245 is an antibody targeting SLITRK6. Also known as Rabbit Polyclonal to Human SLITRK6. Reactive in Gibbon, Chimpanzee, Hamster, Human, Rat
Predicted Reactivity: Gorilla, Monkey, Mouse, Pig (at least 90% immunogen sequence identity). Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for SLITRK6. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
SLIT and NTRK-like protein 6
NCBI Official Synonym Full Names
SLIT and NTRK-like family, member 6
NCBI Official Symbol
SLITRK6
NCBI Official Synonym Symbols
DFNMYP
UniProt Protein Name
SLIT and NTRK-like protein 6
UniProt Gene Name
SLITRK6
UniProt Entry Name
SLIK6_HUMAN
NCBI Protein Information
SLIT and NTRK-like protein 6; 4832410J21Rik; slit and trk like gene 6

NCBI Summary for SLITRK6

This gene encodes a member of the SLITRK protein family. Members of this family are integral membrane proteins that are characterized by two N-terminal leucine-rich repeat (LRR) domains and a C-terminal region that shares homology with trk neurotrophin receptors. This protein functions as a regulator of neurite outgrowth required for normal hearing and vision. Mutations in this gene are a cause of myopia and deafness. [provided by RefSeq, Dec 2014]
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UniProt Comments for SLITRK6

SLITRK6: Suppresses neurite outgrowth. Belongs to the SLITRK family.

Protein type: Membrane protein, integral; Cell surface

Chromosomal Location of Human Ortholog: 13q31.1

Cellular Component: cell surface; integral to plasma membrane

Biological Process: lens development in camera-type eye; vestibulocochlear nerve development; synaptogenesis; sensory perception of sound; startle response; visual perception; axonogenesis; adult locomotory behavior; multicellular organism growth; auditory receptor cell morphogenesis; auditory behavior; linear vestibuloocular reflex

Disease: Deafness And Myopia
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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