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SLC39A6 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS243331

LIV-1/Slc39A6 belongs to the LZT (LIV-1 subfamily of ZIP zinc transporters) subfamily of zinc transporters. These proteins control the levels of zinc in cells, which is an essential ion for cells that plays a role in controlling the cellular processes of the… More details

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Product Overview

Online Datasheet in PDF
Product Name
SLC39A6 / LIV-1, Polyclonal Antibody
Full Product Name
Rabbit Polyclonal to Human SLC39A6 / LIV-1
Product Gene Name
Product Synonym Gene Name
LIV-1
Product Synonym Names
Anti-SLC39A6 / LIV-1 Antibody (Internal) IHC-plus; SLC39A6; LIV1; LIV-1; ZIP-6; Zrt- and Irt-like protein 6; Zinc transporter ZIP6; ZIP6; Human SLC39A6; LIV-1
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Gorilla, Human
Predicted Reactivity: Orangutan, Monkey (at least 90% immunogen sequence identity)
Form/Format
PBS, 0.1% sodium azide.
Purity/Purification
Immunoaffinity Purified
Concentration
1 mg/ml (lot specific)
Specificity
Human SLC39A6. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Preparation and Storage
Long term: -70 degree C; Short term: +4 degree C
Molecular Weight
48,605 Da
OMIM
608731
3D Structure
ModBase 3D Structure for Q13433
Target Species
Human
Immunogen Description
Synthetic 19 amino acid peptide from internal region of human SLC39A6. Percent identity with other species by BLAST analysis: Human, Gorilla (100%); Orangutan, Monkey (95%); Gibbon, Marmoset (89%).
Immunogen Type
Synthetic peptide
Immunogen
SLC39A6 / LIV-1 antibody was raised against synthetic 19 amino acid peptide from internal region of human SLC39A6. Percent identity with other species by BLAST analysis: Human, Gorilla (100%); Orangutan, Monkey (95%); Gibbon, Marmoset (89%).
Antigen Modification
Internal
Applications Tested/Suitable for anti-SLC39A6 antibody
Immunohistochemistry (IHC - Paraffin)
Application Notes for anti-SLC39A6 antibody
IHC-P (10 ug/ml)

Immunohistochemistry (IHC) of anti-SLC39A6 antibody

Anti-SLC39A6 antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Rabbit Anti-SLC39A6 Polyclonal Antibody – Cat# MBS243331

Other Notes

Small volumes of anti-SLC39A6 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SLC39A6 purchase

MBS243331 is an antibody targeting SLC39A6. Also known as Rabbit Polyclonal to Human SLC39A6 / LIV-1. Reactive in Gorilla, Human
Predicted Reactivity: Orangutan, Monkey (at least 90% immunogen sequence identity). Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for SLC39A6. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
zinc transporter ZIP6 isoform 1
NCBI Official Synonym Full Names
solute carrier family 39 (zinc transporter), member 6
NCBI Official Symbol
SLC39A6
NCBI Official Synonym Symbols
LIV-1
UniProt Protein Name
Zinc transporter ZIP6
UniProt Synonym Protein Names
Estrogen-regulated protein LIV-1; Solute carrier family 39 member 6; Zrt- and Irt-like protein 6; ZIP-6
Protein Family
UniProt Gene Name
SLC39A6
UniProt Synonym Gene Names
LIV1; ZIP6; ZIP-6
UniProt Entry Name
S39A6_HUMAN
NCBI Protein Information
zinc transporter ZIP6; ZIP-6; zrt- and Irt-like protein 6; estrogen-regulated protein LIV-1; LIV-1 protein, estrogen regulated; solute carrier family 39 member 6; solute carrier family 39 (metal ion transporter), member 6

NCBI Summary for SLC39A6

Zinc is an essential cofactor for hundreds of enzymes. It is involved in protein, nucleic acid, carbohydrate, and lipid metabolism, as well as in the control of gene transcription, growth, development, and differentiation. SLC39A6 belongs to a subfamily of proteins that show structural characteristics of zinc transporters (Taylor and Nicholson, 2003 [PubMed 12659941]).[supplied by OMIM, Mar 2008]
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UniProt Comments for SLC39A6

SLC39A6: May act as a zinc-influx transporter. Belongs to the ZIP transporter (TC 2.A.5) family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Membrane protein, multi-pass; Transporter, SLC family; Transporter

Chromosomal Location of Human Ortholog: 18q12.2

Cellular Component: cell surface; integral to plasma membrane; endoplasmic reticulum; plasma membrane

Molecular Function: zinc ion transmembrane transporter activity

Biological Process: cellular zinc ion homeostasis; transmembrane transport
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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