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CXXC4 Antibody – Goat Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS243382

MBS243382 is an antibody targeting CXXC4. Also known as Goat Polyclonal to Human CXXC4. Reactive in Gibbon, Dog, Xenopus, Gorilla, Human, Monkey, Mouse, Rabbit, Rat. Host: Goat. More details

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Product Overview

Product Name
CXXC4, Polyclonal Antibody
Full Product Name
Goat Polyclonal to Human CXXC4
Product Gene Name
Product Synonym Names
Anti-CXXC4 Antibody (C-Terminus) IHC-plus; CXXC4; CXXC finger protein 4; CXXC finger 4; IDAX; Human CXXC4
Clonality
Polyclonal
Host
Goat
Species Reactivity
Gibbon, Dog, Xenopus, Gorilla, Human, Monkey, Mouse, Rabbit, Rat
Form/Format
Tris-buffered saline, pH 7.3, 0.5% BSA, 0.02% sodium azide
Purity/Purification
Immunoaffinity Purified
Concentration
0.5 mg/ml (lot specific)
Specificity
Human CXXC4.
Preparation and Storage
Store at -20 degree C. Minimize freezing and thawing.
Molecular Weight
20,978 Da
OMIM
611645
3D Structure
ModBase 3D Structure for Q9H2H0
Target Species
Human
Immunogen Description
Synthetic peptide C-GTSLERTPVPSAEA from the C-terminus (near) of human CXXC4 (NP_079488.1). Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Dog, Rabbit, Opossum, Xenopus (100%); Elephant (93%).
Immunogen Type
Synthetic peptide
Immunogen
CXXC4 antibody was raised against synthetic peptide C-GTSLERTPVPSAEA from the C-terminus (near) of human CXXC4 (NP_079488.1). Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Dog, Rabbit, Opossum, Xenopus (100%); Elephant (93%).
Antigen Modification
C-Terminus
Applications Tested/Suitable for anti-CXXC4 antibody
Immunohistochemistry (IHC - Paraffin), ELISA (EIA)
Application Notes for anti-CXXC4 antibody
ELISA, IHC-P (3.75 ug/ml)
Usage: Western Blot: Preliminary experiments in Human Brain (Cerebellum, Hippocampus) lysates gave no specific signal but low background (at antibody concentration up to 1 ug/ml).

Immunohistochemistry (IHC) of anti-CXXC4 antibody

Anti-CXXC4 antibody IHC of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 3.75 ug/ml.
Goat Anti-CXXC4 Polyclonal Antibody – Cat# MBS243382

Other Notes

Small volumes of anti-CXXC4 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for CXXC4. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
CXXC-type zinc finger protein 4
NCBI Official Synonym Full Names
CXXC finger protein 4
NCBI Official Symbol
CXXC4
NCBI Official Synonym Symbols
IDAX
UniProt Protein Name
CXXC-type zinc finger protein 4
UniProt Synonym Protein Names
Inhibition of the Dvl and axin complex protein
UniProt Gene Name
CXXC4
UniProt Synonym Gene Names
IDAX
UniProt Entry Name
CXXC4_HUMAN
NCBI Protein Information
CXXC-type zinc finger protein 4; CXXC finger 4; inhibition of the Dvl and axin complex protein; Dvl-binding protein IDAX (inhibition of the Dvl and Axin complex)

UniProt Comments for CXXC4

CXXC4: Acts as a negative regulator of the Wnt signaling pathway via its interaction with DVL1.

Protein type: Inhibitor

Chromosomal Location of Human Ortholog: 4q24

Cellular Component: cytoplasmic membrane-bound vesicle; cytoplasm; cytoplasmic vesicle

Molecular Function: DNA binding; zinc ion binding; PDZ domain binding

Biological Process: zygotic determination of dorsal/ventral axis; Wnt receptor signaling pathway; negative regulation of Wnt receptor signaling pathway
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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