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AP3M1 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS243438

MBS243438 is an antibody targeting AP3M1. Also known as Rabbit Polyclonal to Human AP3M1. Reactive in Bovine, Chicken, Dog, Hamster, Horse, Human. Host: Rabbit. More details

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Product Overview

Product Name
AP3M1, Polyclonal Antibody
Full Product Name
Rabbit Polyclonal to Human AP3M1
Product Gene Name
Product Synonym Names
Anti-AP3M1 Antibody (aa140-190) IHC-plus; AP3M1; AP-3 complex subunit mu-1; Mu3A-adaptin; Mu-adaptin 3A; Human AP3M1
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Bovine, Chicken, Dog, Hamster, Horse, Human
Form/Format
PBS, 0.05% BSA, 0.05% sodium azide
Purity/Purification
Protein A Purified
Concentration
0.5 mg/ml (lot specific)
Specificity
Human AP3M1
Preparation and Storage
Store at 4 degree C, stable for 6 months. For long term storage, aliquot and store at -20 degree C.
Molecular Weight
46,939 Da
OMIM
610366
3D Structure
ModBase 3D Structure for Q9Y2T2
Target Species
Human
Immunogen Description
Amino acids 140-190 of human AP3 subunit M1.
Immunogen Type
Synthetic peptide
Immunogen
AP3M1 antibody was raised against amino acids 140-190 of human AP3 subunit M1.
Antigen Modification
aa140-190
Applications Tested/Suitable for anti-AP3M1 antibody
Immunohistochemistry (IHC - Paraffin), Western Blot (WB)
Application Notes for anti-AP3M1 antibody
IHC-P (10 ug/ml), WB (3 - 5 ug/ml)

Immunohistochemistry (IHC) of anti-AP3M1 antibody

Anti-AP3M1 antibody IHC of human lung, respiratory epithelium. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 10 ug/ml.
Rabbit Anti-AP3M1 Polyclonal Antibody – Cat# MBS243438

Other Notes

Small volumes of anti-AP3M1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for AP3M1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
AP-3 complex subunit mu-1
NCBI Official Synonym Full Names
adaptor-related protein complex 3, mu 1 subunit
NCBI Official Symbol
AP3M1
UniProt Protein Name
AP-3 complex subunit mu-1
UniProt Synonym Protein Names
AP-3 adaptor complex mu3A subunit; Adaptor-related protein complex 3 subunit mu-1; Mu-adaptin 3A; Mu3A-adaptin
Protein Family
UniProt Gene Name
AP3M1
UniProt Entry Name
AP3M1_HUMAN
NCBI Protein Information
AP-3 complex subunit mu-1; mu3A-adaptin; mu-adaptin 3A; AP-3 adapter complex mu3A subunit; AP-3 adaptor complex mu3A subunit; clathrin adaptor complex AP3, mu-3A subunit; adapter-related protein complex 3 mu-1 subunit; adapter-related protein complex 3 subunit mu-1; adaptor-related protein complex 3 subunit mu-1

NCBI Summary for AP3M1

The protein encoded by this gene is the medium subunit of AP-3, which is an adaptor-related protein complex associated with the Golgi region as well as more peripheral intracellular structures. AP-3 facilitates the budding of vesicles from the Golgi membrane and may be directly involved in protein sorting to the endosomal/lysosomal system. AP-3 is a heterotetrameric protein complex composed of two large subunits (delta and beta3), a medium subunit (mu3), and a small subunit (sigma 3). Mutations in one of the large subunits of AP-3 have been associated with the Hermansky-Pudlak syndrome, a genetic disorder characterized by defective lysosome-related organelles. Alternatively spliced transcript variants encoding the same protein have been observed. [provided by RefSeq, Jul 2008]
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UniProt Comments for AP3M1

AP3M1: Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. Belongs to the adaptor complexes medium subunit family.

Protein type: Adaptor/scaffold

Chromosomal Location of Human Ortholog: 10q22.2

Cellular Component: Golgi apparatus; clathrin adaptor complex; cytoplasmic vesicle membrane; lysosome; lysosomal membrane

Molecular Function: protein binding; Rab GTPase binding

Biological Process: protein targeting to lysosome; anterograde synaptic vesicle transport; anterograde axon cargo transport
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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